CA2011658A1 - Amides de 1h-indole-2-acide-carboxylique-n-(1,4-benzodiazepin-3-yl) cyclises en 1 et 7 - Google Patents

Amides de 1h-indole-2-acide-carboxylique-n-(1,4-benzodiazepin-3-yl) cyclises en 1 et 7

Info

Publication number: CA2011658A1
Authority: CA; Canada
Prior art keywords: lower alkyl; represents hydrogen; halogen; carbon atoms; annelated
Prior art date: 1989-03-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2011658A

Other languages

English (en)

Other versions

CA2011658C (fr

Inventor

Harald Waldeck

Werner Benson

Horst Zeugner

Klaus-Ullrich Wolf

Peter-Colin Gregory

Derk Hamminga

Ineke Van Wijngaarden

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Abbott Products GmbH

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-08

Filing date

1990-03-07

Publication date

1990-09-08

1990-03-07 Application filed by Individual filed Critical Individual

1990-09-08 Publication of CA2011658A1 publication Critical patent/CA2011658A1/fr

2000-05-16 Application granted granted Critical

2000-05-16 Publication of CA2011658C publication Critical patent/CA2011658C/fr

2010-03-07 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

HCUARRIEZVDMPT-UHFFFAOYSA-N Indole-2-carboxylic acid Chemical compound C1=CC=C2NC(C(=O)O)=CC2=C1 HCUARRIEZVDMPT-UHFFFAOYSA-N 0.000 title 1
150000001408 amides Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
229910052736 halogen Inorganic materials 0.000 abstract 4
150000002367 halogens Chemical group 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 3
YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
125000002947 alkylene group Chemical group 0.000 abstract 1
125000005530 alkylenedioxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
229930192474 thiophene Natural products 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA002011658A 1989-03-08 1990-03-07 Amides de 1h-indole-2-acide-carboxylique-n-(1,4-benzodiazepin-3-yl) cyclises en 1 et 7 Expired - Fee Related CA2011658C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3907389A DE3907389A1 (de)	1989-03-08	1989-03-08	Neue 1,7-anellierte 1h-indol-carbonsaeure-n-(5-alkyl-1,4-benzodiazepin-3-yl)amide
DEP3907389.0		1989-03-08

Publications (2)

Publication Number	Publication Date
CA2011658A1 true CA2011658A1 (fr)	1990-09-08
CA2011658C CA2011658C (fr)	2000-05-16

Family

ID=6375778

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002011658A Expired - Fee Related CA2011658C (fr)	1989-03-08	1990-03-07	Amides de 1h-indole-2-acide-carboxylique-n-(1,4-benzodiazepin-3-yl) cyclises en 1 et 7

Country Status (4)

Country	Link
CA (1)	CA2011658C (fr)
DD (1)	DD292458A5 (fr)
DE (1)	DE3907389A1 (fr)
ZA (1)	ZA901671B (fr)

1989
- 1989-03-08 DE DE3907389A patent/DE3907389A1/de not_active Withdrawn
1990
- 1990-03-05 ZA ZA901671A patent/ZA901671B/xx unknown
- 1990-03-06 DD DD90338440A patent/DD292458A5/de not_active IP Right Cessation
- 1990-03-07 CA CA002011658A patent/CA2011658C/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2011658C (fr)	2000-05-16
DE3907389A1 (de)	1990-09-13
ZA901671B (en)	1990-11-28
DD292458A5 (de)	1991-08-01

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Legal Events

Date	Code	Title	Description
1997-02-21	EEER	Examination request
2007-03-07	MKLA	Lapsed