CA2012045A1 - Composes pharmaceutiques de la 5'-desoxy-51-methylthioadenosine, de la s-adenosylmethionine et de leurs sels pour stimuler la pousse des cheveux chez les chauves - Google Patents

Composes pharmaceutiques de la 5'-desoxy-51-methylthioadenosine, de la s-adenosylmethionine et de leurs sels pour stimuler la pousse des cheveux chez les chauves

Info

Publication number: CA2012045A1
Authority: CA; Canada
Prior art keywords: adenosylmethionine; baldness; deoxy; subjects suffering; pharmaceutical compositions
Prior art date: 1989-03-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2012045A

Other languages

English (en)

Other versions

CA2012045C (fr

Inventor

Emanuela Maggioni Moratti

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

KNOLL-RAVIZZA FARMACEUTICI SpA

Original Assignee

Bioresearch SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-13

Filing date

1990-03-13

Publication date

1990-09-13

1990-03-13 Application filed by Bioresearch SRL filed Critical Bioresearch SRL

1990-09-13 Publication of CA2012045A1 publication Critical patent/CA2012045A1/fr

2001-02-13 Application granted granted Critical

2001-02-13 Publication of CA2012045C publication Critical patent/CA2012045C/fr

2010-03-13 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

201000004384 Alopecia Diseases 0.000 title abstract 3
WUUGFSXJNOTRMR-WOIOKPISSA-N 5'-deoxy-5'-methylthioadenosine Chemical compound O[C@@H]1[C@@H](O)[C@H](CSC)O[C@H]1N1C2=NC=NC(N)=C2N=C1 WUUGFSXJNOTRMR-WOIOKPISSA-N 0.000 title abstract 2
WUUGFSXJNOTRMR-UHFFFAOYSA-N 5alpha-Hydroxy-3abeta,5beta,8-trimethyl-1-(1,5-dimethyl-hexen-(4)-yl)-4abetaH,7abetaH-dicyclopentano[a.d]cyclooctaen-(8) Natural products OC1C(O)C(CSC)OC1N1C2=NC=NC(N)=C2N=C1 WUUGFSXJNOTRMR-UHFFFAOYSA-N 0.000 title abstract 2
MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 title abstract 2
229960001570 ademetionine Drugs 0.000 title abstract 2
230000003779 hair growth Effects 0.000 title abstract 2
230000003676 hair loss Effects 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
206010068168 androgenetic alopecia Diseases 0.000 abstract 1
201000002996 androgenic alopecia Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Birds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cosmetics (AREA)
Saccharide Compounds (AREA)

CA002012045A 1989-03-13 1990-03-13 Composes pharmaceutiques de la 5'-desoxy-51-methylthioadenosine, de la s-adenosylmethionine et de leurs sels pour stimuler la pousse des cheveux chez les chauves Expired - Fee Related CA2012045C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT19747A/89		1989-03-13
IT8919747A IT1229479B (it)	1989-03-13	1989-03-13	Impiego di 5' deossi 5' metiltioadenosina, di s adenosilmetionina e dei loro sali per la preparazione di composizioni farmaceutiche atte a favorire la crescita dei capelli in soggetti affetti da calvizie e composizioni farmaceutiche relative.

Publications (2)

Publication Number	Publication Date
CA2012045A1 true CA2012045A1 (fr)	1990-09-13
CA2012045C CA2012045C (fr)	2001-02-13

Family

ID=11160891

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002012045A Expired - Fee Related CA2012045C (fr)	1989-03-13	1990-03-13	Composes pharmaceutiques de la 5'-desoxy-51-methylthioadenosine, de la s-adenosylmethionine et de leurs sels pour stimuler la pousse des cheveux chez les chauves

Country Status (12)

Country	Link
EP (1)	EP0387757B1 (fr)
JP (1)	JPH0778012B2 (fr)
KR (1)	KR900013935A (fr)
AT (1)	ATE98467T1 (fr)
AU (1)	AU637999B2 (fr)
CA (1)	CA2012045C (fr)
DE (1)	DE69005160T2 (fr)
DK (1)	DK0387757T3 (fr)
ES (1)	ES2062138T3 (fr)
IT (1)	IT1229479B (fr)
PH (1)	PH30798A (fr)
ZA (1)	ZA901930B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1247903B (it) *	1991-02-25	1995-01-05	Bioresearch Spa	Impiego della s-adenosil-l-metionina nel trattamento della colestasi intraepatica da nutrizione parenterale totale
JP2636118B2 (ja) *	1991-09-10	1997-07-30	三省製薬株式会社	育毛剤
AU659861B2 (en) *	1991-09-10	1995-06-01	Sansho Seiyaku Co., Ltd.	Preparation for promoting hair growth
US7071230B2 (en)	1997-10-02	2006-07-04	Board Of Trustees Of Southern Illinois University	Therapeutic use of D-methionine to reduce the toxicity of noise
DE69914158T2 (de) *	1998-10-26	2004-10-14	Shiseido Co. Ltd.	Adenosin enthaltendes Haartonikum
AU2459100A (en) *	1999-02-10	2000-08-29	Taisho Pharmaceutical Co., Ltd.	Hair growth stimulants and method for screening substance having hair growth stimulating effect
DK1325740T3 (da)	2001-12-12	2004-08-16	Chemistry & Health Int Bv	Stabile granulater indeholdende s-adenosylmethionin og fremgangsmåde til fremstilling deraf
JPWO2005044205A1 (ja) *	2003-11-11	2007-05-17	株式会社資生堂	毛髪の太毛化の方法及び組成物
ITMI20032393A1 (it) *	2003-12-05	2005-06-06	Applied Pharma Res	Composizioni contenenti metilioadenosina-mta-e loro uso topico.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2313937A1 (fr) *	1975-06-09	1977-01-07	Anvar	Medicament a base de 5' thioethers de l'adenosine
IT1169772B (it) *	1983-08-24	1987-06-03	Bioresearch Spa	Composizioni terapeutiche per uso orale contenenti sali stabili della s-adenosil-l-metionina
IT1169774B (it) *	1983-08-24	1987-06-03	Bioresearch Spa	Composizioni terapeutiche iniettabili contenenti sali stabili della s-adenosil-l-metionina
NL8302984A (nl) *	1983-08-26	1985-03-18	Philips Nv	Beeldweergeefinrichting met een ruisdetektor.

1989
- 1989-03-13 IT IT8919747A patent/IT1229479B/it active
1990
- 1990-03-12 DK DK90104641.7T patent/DK0387757T3/da active
- 1990-03-12 DE DE90104641T patent/DE69005160T2/de not_active Expired - Lifetime
- 1990-03-12 ES ES90104641T patent/ES2062138T3/es not_active Expired - Lifetime
- 1990-03-12 AT AT90104641T patent/ATE98467T1/de not_active IP Right Cessation
- 1990-03-12 EP EP90104641A patent/EP0387757B1/fr not_active Expired - Lifetime
- 1990-03-13 ZA ZA901930A patent/ZA901930B/xx unknown
- 1990-03-13 AU AU51273/90A patent/AU637999B2/en not_active Ceased
- 1990-03-13 JP JP2060127A patent/JPH0778012B2/ja not_active Expired - Fee Related
- 1990-03-13 CA CA002012045A patent/CA2012045C/fr not_active Expired - Fee Related
- 1990-03-13 KR KR1019900003302A patent/KR900013935A/ko not_active Ceased
- 1990-03-13 PH PH40185A patent/PH30798A/en unknown

Also Published As

Publication number	Publication date
CA2012045C (fr)	2001-02-13
IT8919747A0 (it)	1989-03-13
ATE98467T1 (de)	1994-01-15
DE69005160D1 (de)	1994-01-27
AU637999B2 (en)	1993-06-17
JPH0778012B2 (ja)	1995-08-23
PH30798A (en)	1998-10-17
IT1229479B (it)	1991-09-03
DE69005160T2 (de)	1994-03-31
EP0387757B1 (fr)	1993-12-15
AU5127390A (en)	1990-11-01
ZA901930B (en)	1990-12-28
EP0387757A3 (en)	1990-12-12
EP0387757A2 (fr)	1990-09-19
JPH0363225A (ja)	1991-03-19
ES2062138T3 (es)	1994-12-16
DK0387757T3 (da)	1994-03-21
KR900013935A (ko)	1990-10-22

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Legal Events

Date	Code	Title	Description
1997-03-13	EEER	Examination request
2005-03-14	MKLA	Lapsed