CA2012093A1 - Procede de production de 2,2'-cyclocitidine et de leurs analogues - Google Patents

Procede de production de 2,2'-cyclocitidine et de leurs analogues

Info

Publication number: CA2012093A1
Authority: CA; Canada
Prior art keywords: cyclocytidine; analogues; producing; compound; dialkylstannylene
Prior art date: 1990-03-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA 2012093

Other languages

English (en)

Other versions

CA2012093C (fr

Inventor

Khashayar Karimian

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Apotex Pharmachem Inc

Original Assignee

Acic Canada Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-13

Filing date

1990-03-13

Publication date

1991-09-13

1990-03-13 Priority to CA 2012093 priority Critical patent/CA2012093C/fr

1990-03-13 Application filed by Acic Canada Inc filed Critical Acic Canada Inc

1991-03-13 Priority to PCT/CA1991/000077 priority patent/WO1991013900A1/fr

1991-03-13 Priority to HU9202906A priority patent/HUT61566A/hu

1991-03-13 Priority to AT91906244T priority patent/ATE119541T1/de

1991-03-13 Priority to AU74737/91A priority patent/AU7473791A/en

1991-03-13 Priority to BR919106158A priority patent/BR9106158A/pt

1991-03-13 Priority to DE69108014T priority patent/DE69108014T2/de

1991-03-13 Priority to EP91906244A priority patent/EP0521923B1/fr

1991-09-13 Publication of CA2012093A1 publication Critical patent/CA2012093A1/fr

1994-09-27 Priority to US08/313,579 priority patent/US5610292A/en

1995-12-26 Application granted granted Critical

1995-12-26 Publication of CA2012093C publication Critical patent/CA2012093C/fr

2010-03-13 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

BBDAGFIXKZCXAH-CCXZUQQUSA-N ancitabine Chemical compound N=C1C=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3OC2=N1 BBDAGFIXKZCXAH-CCXZUQQUSA-N 0.000 title abstract 3
-1 cytidine compound Chemical class 0.000 abstract 2
UHDGCWIWMRVCDJ-UHFFFAOYSA-N 1-beta-D-Xylofuranosyl-NH-Cytosine Natural products O=C1N=C(N)C=CN1C1C(O)C(O)C(CO)O1 UHDGCWIWMRVCDJ-UHFFFAOYSA-N 0.000 abstract 1
UHDGCWIWMRVCDJ-CCXZUQQUSA-N Cytarabine Chemical compound O=C1N=C(N)C=CN1[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O1 UHDGCWIWMRVCDJ-CCXZUQQUSA-N 0.000 abstract 1
UHDGCWIWMRVCDJ-PSQAKQOGSA-N Cytidine Natural products O=C1N=C(N)C=CN1[C@@H]1[C@@H](O)[C@@H](O)[C@H](CO)O1 UHDGCWIWMRVCDJ-PSQAKQOGSA-N 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
230000000118 anti-neoplastic effect Effects 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
229960000684 cytarabine Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA 2012093 1990-03-13 1990-03-13 Procede de production de 2,2'-cyclocitidine et de leurs analogues Expired - Fee Related CA2012093C (fr)

Priority Applications (9)

Application Number	Priority Date	Filing Date	Title
CA 2012093 CA2012093C (fr)	1990-03-13	1990-03-13	Procede de production de 2,2'-cyclocitidine et de leurs analogues
HU9202906A HUT61566A (en)	1990-03-13	1991-03-13	Process for producing 2,2'-o-cyclonucleosides, nucleosides and their analogous compounds
AT91906244T ATE119541T1 (de)	1990-03-13	1991-03-13	Verfahren zur herstellung von nucleosiden und ihre analogen.
AU74737/91A AU7473791A (en)	1990-03-13	1991-03-13	Process for producing 2,2'-o-cyclonucleosides, nucleosides, and analogs thereof
PCT/CA1991/000077 WO1991013900A1 (fr)	1990-03-13	1991-03-13	Procede de production de 2-2'-o-cyclonucleosides, nucleosides et analogues
BR919106158A BR9106158A (pt)	1990-03-13	1991-03-13	Processo para produzir 2,2'-o-ciclonucleosideos,nucleosideos e seus analogos
DE69108014T DE69108014T2 (de)	1990-03-13	1991-03-13	Verfahren zur herstellung von nucleosiden und ihre analogen.
EP91906244A EP0521923B1 (fr)	1990-03-13	1991-03-13	Procede de production de nucleosides et analogues
US08/313,579 US5610292A (en)	1990-03-13	1994-09-27	Process for producing 2,2'-o-cyclonucleosides nucleosides, and analogs thereof

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CA 2012093 CA2012093C (fr)	1990-03-13	1990-03-13	Procede de production de 2,2'-cyclocitidine et de leurs analogues

Publications (2)

Publication Number	Publication Date
CA2012093A1 true CA2012093A1 (fr)	1991-09-13
CA2012093C CA2012093C (fr)	1995-12-26

Family

ID=4144515

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA 2012093 Expired - Fee Related CA2012093C (fr)	1990-03-13	1990-03-13	Procede de production de 2,2'-cyclocitidine et de leurs analogues

Country Status (1)

Country	Link
CA (1)	CA2012093C (fr)

1990
- 1990-03-13 CA CA 2012093 patent/CA2012093C/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2012093C (fr)	1995-12-26

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Legal Events

Date	Code	Title	Description
1990-07-13	EEER	Examination request
2001-03-13	MKLA	Lapsed