CA2013649A1 - Separation des isomeres de derives de furo (3,4-c) pyridine - Google Patents

Separation des isomeres de derives de furo (3,4-c) pyridine

Info

Publication number: CA2013649A1
Authority: CA; Canada
Prior art keywords: furo; separation; pyridine; isomers; pyridine derivatives
Prior art date: 1989-04-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2013649A

Other languages

English (en)

Other versions

CA2013649C (fr

Inventor

Andre Esanu

Charles Eck

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ipsen Pharma SAS

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-03

Filing date

1990-04-02

Publication date

1990-10-03

1990-04-02 Application filed by Individual filed Critical Individual

1990-10-03 Publication of CA2013649A1 publication Critical patent/CA2013649A1/fr

1996-07-02 Application granted granted Critical

1996-07-02 Publication of CA2013649C publication Critical patent/CA2013649C/fr

2010-04-02 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

238000000926 separation method Methods 0.000 title abstract 2
GJVNMIQVQXYJCP-UHFFFAOYSA-N furo[3,4-c]pyridine Chemical class C1=NC=CC2=[C]OC=C21 GJVNMIQVQXYJCP-UHFFFAOYSA-N 0.000 title 1
SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 title 1
150000002170 ethers Chemical class 0.000 abstract 2
BIRWRIAEWIXFHT-UHFFFAOYSA-N furo[3,4-c]pyridin-7-ol Chemical class OC1=CN=CC2=COC=C12 BIRWRIAEWIXFHT-UHFFFAOYSA-N 0.000 abstract 2
150000002772 monosaccharides Chemical class 0.000 abstract 2
-1 furo[3,4-c] pyridine 7-yl Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000010956 selective crystallization Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

CA002013649A 1989-04-03 1990-04-02 Separation des isomeres de derives de furo (3,4-c) pyridine Expired - Fee Related CA2013649C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898907480A GB8907480D0 (en)	1989-04-03	1989-04-03	Separation of insomers of furo(3,4-c)pyridine derivatives
GB8907480		1989-04-03

Publications (2)

Publication Number	Publication Date
CA2013649A1 true CA2013649A1 (fr)	1990-10-03
CA2013649C CA2013649C (fr)	1996-07-02

Family

ID=10654383

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002013649A Expired - Fee Related CA2013649C (fr)	1989-04-03	1990-04-02	Separation des isomeres de derives de furo (3,4-c) pyridine

Country Status (14)

Country	Link
US (1)	US5047537A (fr)
JP (1)	JP2673029B2 (fr)
BE (1)	BE1002438A3 (fr)
CA (1)	CA2013649C (fr)
CH (1)	CH680733A5 (fr)
DE (1)	DE4010657C2 (fr)
ES (1)	ES2019245A6 (fr)
FR (1)	FR2645151B1 (fr)
GB (2)	GB8907480D0 (fr)
HK (1)	HK92693A (fr)
IE (1)	IE64950B1 (fr)
IT (1)	IT1240735B (fr)
NL (1)	NL194915C (fr)
WO (1)	WO1993015082A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8808001D0 (en) *	1988-04-06	1988-05-05	Scras	Stereospecific preparative process for furol(3,4-c)pyridine derivatives
US5130252A (en) *	1990-05-14	1992-07-14	Synthetech, Inc.	Resolution of furopyridine enantiomers and synthetic precursors thereof
GB0221494D0 (en) *	2002-09-16	2002-10-23	Generics Uk Ltd	Novel processes for the preparation of 1.3-dihydro-6-methylfuro (3,4-c) pyndin derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB779318A (en) *	1954-10-21	1957-07-17	Belfanti Ist Sieroterap Milan	Process for separating the d-(-)-threo-1-(p-nitrophenyl)-2-amino 1,3-propanediol from the racemic compound
IN156817B (fr) *	1981-02-10	1985-11-09	Scras
GB8327817D0 (en) *	1983-10-18	1983-11-16	Scras	4-halo-furo-(3 4-c)-pyridine derivatives
GB8330658D0 (en) *	1983-11-17	1983-12-29	Scras	7-carboxymethoxy-furo-(3,4-c)-pyridine derivatives
GB8402740D0 (en) *	1984-02-02	1984-03-07	Scras	Furo-(3 4-c)-pyridine derivatives
DE3412939A1 (de) *	1984-04-06	1985-10-17	Behringwerke Ag, 3550 Marburg	Substrate fuer hydrolasen, verfahren zu ihrer herstellung und ihre verwendung
GB8422379D0 (en) *	1984-09-05	1984-10-10	Scras	Derivatives
GB8808001D0 (en) *	1988-04-06	1988-05-05	Scras	Stereospecific preparative process for furol(3,4-c)pyridine derivatives

1989
- 1989-04-03 GB GB898907480A patent/GB8907480D0/en active Pending
1990
- 1990-03-28 NL NL9000730A patent/NL194915C/nl not_active IP Right Cessation
- 1990-03-29 CH CH1047/90A patent/CH680733A5/fr not_active IP Right Cessation
- 1990-03-30 BE BE9000359A patent/BE1002438A3/fr not_active IP Right Cessation
- 1990-04-02 CA CA002013649A patent/CA2013649C/fr not_active Expired - Fee Related
- 1990-04-02 IT IT19913A patent/IT1240735B/it active IP Right Grant
- 1990-04-02 FR FR9004160A patent/FR2645151B1/fr not_active Expired - Lifetime
- 1990-04-02 US US07/598,653 patent/US5047537A/en not_active Expired - Lifetime
- 1990-04-02 IE IE118990A patent/IE64950B1/en not_active IP Right Cessation
- 1990-04-02 WO PCT/FR1990/000228 patent/WO1993015082A1/fr not_active Ceased
- 1990-04-02 ES ES9000939A patent/ES2019245A6/es not_active Expired - Lifetime
- 1990-04-03 DE DE4010657A patent/DE4010657C2/de not_active Expired - Lifetime
- 1990-04-03 GB GB9007524A patent/GB2230006B/en not_active Expired - Lifetime
- 1990-04-03 JP JP2087598A patent/JP2673029B2/ja not_active Expired - Fee Related
1993
- 1993-09-09 HK HK926/93A patent/HK92693A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH02289578A (ja)	1990-11-29
CH680733A5 (fr)	1992-10-30
CA2013649C (fr)	1996-07-02
FR2645151A1 (fr)	1990-10-05
IE64950B1 (en)	1995-09-20
IT1240735B (it)	1993-12-17
DE4010657C2 (de)	1999-01-28
IT9019913A1 (it)	1991-10-02
HK92693A (en)	1993-09-17
WO1993015082A1 (fr)	1993-08-05
DE4010657A1 (de)	1990-10-04
NL194915B (nl)	2003-03-03
FR2645151B1 (fr)	1994-05-20
GB8907480D0 (en)	1989-05-17
GB2230006A (en)	1990-10-10
ES2019245A6 (es)	1991-06-01
IT9019913A0 (it)	1990-04-02
NL194915C (nl)	2003-07-04
JP2673029B2 (ja)	1997-11-05
BE1002438A3 (fr)	1991-02-12
IE901189L (en)	1990-10-03
GB9007524D0 (en)	1990-05-30
NL9000730A (nl)	1990-11-01
US5047537A (en)	1991-09-10
GB2230006B (en)	1992-08-12

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Legal Events

Date	Code	Title	Description
1993-04-05	EEER	Examination request
2005-04-04	MKLA	Lapsed