CA2014884A1 - 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida - Google Patents

5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida

Info

Publication number
CA2014884A1
CA2014884A1 CA2014884A CA2014884A CA2014884A1 CA 2014884 A1 CA2014884 A1 CA 2014884A1 CA 2014884 A CA2014884 A CA 2014884A CA 2014884 A CA2014884 A CA 2014884A CA 2014884 A1 CA2014884 A1 CA 2014884A1
Authority
CA
Canada
Prior art keywords
benzodiazepin
pyrido
dihydro
ones
thiones
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2014884A
Other languages
English (en)
Other versions
CA2014884C (fr
Inventor
Gunther Schmidt (Deceased)
Wolfhard Engel
Volkhard Austel
Karl D. Hargrave
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Boehringer Ingelheim Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2014884A1 publication Critical patent/CA2014884A1/fr
Application granted granted Critical
Publication of CA2014884C publication Critical patent/CA2014884C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002014884A 1989-04-20 1990-04-19 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida Expired - Fee Related CA2014884C (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US34093789A 1989-04-20 1989-04-20
US07/340,937 1989-04-20
US37272889A 1989-06-28 1989-06-28
US07/372,728 1989-06-28
US43892289A 1989-11-17 1989-11-17
US07/438,922 1989-11-17

Publications (2)

Publication Number Publication Date
CA2014884A1 true CA2014884A1 (fr) 1990-10-20
CA2014884C CA2014884C (fr) 1999-09-07

Family

ID=27407433

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002014884A Expired - Fee Related CA2014884C (fr) 1989-04-20 1990-04-19 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida

Country Status (8)

Country Link
EP (1) EP0393530B1 (fr)
JP (1) JP2911956B2 (fr)
AT (1) ATE116320T1 (fr)
CA (1) CA2014884C (fr)
DE (1) DE69015411T2 (fr)
DK (1) DK0393530T3 (fr)
ES (1) ES2066897T3 (fr)
GR (1) GR3015469T3 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0475231A1 (fr) * 1990-09-10 1992-03-18 F. Hoffmann-La Roche Ag Benzodiazépines
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
AU5883794A (en) * 1993-01-20 1994-08-15 A. Menarini Industrie Farmaceutiche Riunite S.R.L. Diazepin derivatives and antiviral compositions
US6593337B1 (en) 1999-10-19 2003-07-15 Bristol-Myers Squibb Pharma Company Tricyclic compounds useful as HIV reverse transcriptase inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1542160A (fr) * 1966-10-31 1968-10-11 Thomae Gmbh Dr K Procédé de fabrication de nouvelles 5, 11-dihydro-6h-pyrido-[2, 3-b] [1, 4]-benzodiazépine-6-ones substituées en position 11

Also Published As

Publication number Publication date
GR3015469T3 (en) 1995-06-30
JP2911956B2 (ja) 1999-06-28
ES2066897T3 (es) 1995-03-16
CA2014884C (fr) 1999-09-07
DK0393530T3 (da) 1995-05-22
DE69015411T2 (de) 1995-05-24
ATE116320T1 (de) 1995-01-15
EP0393530B1 (fr) 1994-12-28
EP0393530A1 (fr) 1990-10-24
JPH0363275A (ja) 1991-03-19
DE69015411D1 (de) 1995-02-09

Similar Documents

Publication Publication Date Title
AU579696B2 (en) Disposable, underpants, such as child's training pants and the like
CA2019812A1 (fr) Nouveau 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-ones et leur utilisation dans la prevention et le traitement du sida
CA2030056A1 (fr) 5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepines et leur utilisation pour la prevention ou le traitement de l'infection par le hiv
AU2504288A (en) 2',3'-dideoxy-2'-fluoronucleosides
AU7973994A (en) Combination therapy for hiv infection
AU4856893A (en) 3,3'-disubstituted-1,3-dihydro-2h-pyrrolo{2,3-b}heterocyclic -2-one useful in the treatment of cognitive disorders of man
CA2014885A1 (fr) 6,11-dihydro-5h-pyrido[2,3-b] [1,5] benzodiazepin-5-ones et thiones et leur utilisation dans la prevention et le traitement du sida
AU5491194A (en) Cytotoxic and antiviral compound
TW327171B (en) 2-heteroaryl-5 for prevention or treatment of HIV infection
AU639255B2 (en) Dibenz(b,f)(1,4)oxazepin(and thiazepin)-11(10h)-ones and-thiones
AU634003B2 (en) 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
CA2014884A1 (fr) 5,11-dihydro-6h-pyrido[2,3-b] [1,4] benzodiazepin-6-ones et-thiones et leur utilisation dans la prevention ou le traitement du sida
AU4737993A (en) Novel thiomarinol derivatives, and processes for their preparation
AU7387491A (en) Benzoxazine derivatives, process for their preparation and thier use for the treatment or for the prophylaxis of diseases
AU4186493A (en) Novel phospholipid derivatives
AU6130194A (en) 1,2-dithiole-3-thiones for the treatment of reverse transcriptase-dependent viral infections
GR3034688T3 (en) Use of 6,7-substituted-2-aminotetralines for preparing pharmaceutical compositions useful for the treatment of septic shock, and antipyretic and antiinflammatory pharmaceutical compositions
AU2859892A (en) Aminoalkyl-substituted 5,6-dihydro-dibenz(b,e)azepine-6,11-dione-11-oximes
OA09507A (en) Compositions and methods for treating or preventing AIDS ARC and HIV infection
AU7719491A (en) Therapeutic compound
AU2861589A (en) 1,2,3,6/1,2,5,6-Tetrahydropyridine derivatives
AU6112394A (en) Vinca alkaloids for the treatment of papillomavirus infection
GR3020597T3 (en) Phospholipids for the treatment of multiple sclerosis
AU627874B2 (en) Amino-benzenesulfonamides in the treatment of glaucoma
MX9604346A (es) 8-arilalquil- y 8-arilheteroalquil-5,11-dihidro-6h-dipirido [3,2-b :2',3'-e] [1,4]diazepinas y su uso en la prevencion o tratamiento de infeccion por hiv.

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed