CA2019407A1 - Procede d'hydrogenation stereoselectif - Google Patents

Procede d'hydrogenation stereoselectif

Info

Publication number: CA2019407A1
Authority: CA; Canada
Prior art keywords: hydrogenation process; lysergol; palladium catalyst; catalyst applied; stereoselective hydrogenation
Prior art date: 1989-06-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2019407A

Other languages

English (en)

Other versions

CA2019407C (fr

Inventor

Istvan Polgar

Jozsef Foldesi

Janos Kiss

Major Piroska

Karoly Molnar

Andras Sugar

Tamas Szen

Katalin Balogh

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Richter Gedeon Vegyeszeti Gyar Nyrt

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-27

Filing date

1990-06-20

Publication date

1990-12-27

1990-06-20 Application filed by Individual filed Critical Individual

1990-12-27 Publication of CA2019407A1 publication Critical patent/CA2019407A1/fr

1997-09-30 Application granted granted Critical

1997-09-30 Publication of CA2019407C publication Critical patent/CA2019407C/fr

2010-06-20 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
238000011924 stereoselective hydrogenation Methods 0.000 title 1
KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 4
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
BIXJFIJYBLJTMK-UHFFFAOYSA-N Lysergol Natural products C1=CC(C2=CC(CO)CN(C2C2)C)=C3C2=CNC3=C1 BIXJFIJYBLJTMK-UHFFFAOYSA-N 0.000 abstract 2
239000003054 catalyst Substances 0.000 abstract 2
BIXJFIJYBLJTMK-MEBBXXQBSA-N lysergol Chemical compound C1=CC(C2=C[C@@H](CO)CN([C@@H]2C2)C)=C3C2=CNC3=C1 BIXJFIJYBLJTMK-MEBBXXQBSA-N 0.000 abstract 2
229910052763 palladium Inorganic materials 0.000 abstract 2
UFKTZIXVYHGAES-WDBKCZKBSA-N [(6ar,9r,10ar)-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-yl]methanol Chemical compound C1=CC([C@H]2C[C@@H](CO)CN([C@@H]2C2)C)=C3C2=CNC3=C1 UFKTZIXVYHGAES-WDBKCZKBSA-N 0.000 abstract 1
239000000010 aprotic solvent Substances 0.000 abstract 1
238000005984 hydrogenation reaction Methods 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
230000000707 stereoselective effect Effects 0.000 abstract 1
UFKTZIXVYHGAES-UHFFFAOYSA-N trans-dihydrolysergol Natural products C1=CC(C2CC(CO)CN(C2C2)C)=C3C2=CNC3=C1 UFKTZIXVYHGAES-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CA002019407A 1989-06-27 1990-06-20 Procede d'hydrogenation stereoselectif Expired - Fee Related CA2019407C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU893225A HU203549B (en)	1989-06-27	1989-06-27	New stereoselektive hydrogenating process for producing dihydro-lisergol
HU3225/89		1989-06-27

Publications (2)

Publication Number	Publication Date
CA2019407A1 true CA2019407A1 (fr)	1990-12-27
CA2019407C CA2019407C (fr)	1997-09-30

Family

ID=10963194

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002019407A Expired - Fee Related CA2019407C (fr)	1989-06-27	1990-06-20	Procede d'hydrogenation stereoselectif

Country Status (14)

Country	Link
US (1)	US5097031A (fr)
JP (1)	JPH03128374A (fr)
CA (1)	CA2019407C (fr)
CH (1)	CH680445A5 (fr)
CZ (1)	CZ281957B6 (fr)
DD (1)	DD295378A5 (fr)
DE (1)	DE4020475A1 (fr)
FI (1)	FI92586C (fr)
FR (1)	FR2648815B1 (fr)
HU (1)	HU203549B (fr)
IT (1)	IT1249001B (fr)
NL (1)	NL9001459A (fr)
RU (1)	RU1779253C (fr)
YU (1)	YU124790A (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101481405A (zh)	2001-06-08	2009-07-15	研究及应用科学协会股份有限公司	生长激素释放抑制因子-多巴胺嵌合类似物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE107647T1 (de) *	1984-04-09	1994-07-15	Schering Ag	2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
CH658058A5 (en) *	1984-06-21	1986-10-15	Linnea Sa	Process for preparing lumilysergol derivatives

1989
- 1989-06-27 HU HU893225A patent/HU203549B/hu not_active IP Right Cessation
1990
- 1990-06-20 CA CA002019407A patent/CA2019407C/fr not_active Expired - Fee Related
- 1990-06-21 FR FR909007757A patent/FR2648815B1/fr not_active Expired - Lifetime
- 1990-06-22 US US07/542,168 patent/US5097031A/en not_active Expired - Lifetime
- 1990-06-26 CH CH2131/90A patent/CH680445A5/de not_active IP Right Cessation
- 1990-06-26 FI FI903196A patent/FI92586C/fi not_active IP Right Cessation
- 1990-06-26 NL NL9001459A patent/NL9001459A/nl not_active Application Discontinuation
- 1990-06-26 JP JP2165835A patent/JPH03128374A/ja active Pending
- 1990-06-26 IT IT02076990A patent/IT1249001B/it active IP Right Grant
- 1990-06-26 DD DD90342087A patent/DD295378A5/de not_active IP Right Cessation
- 1990-06-26 YU YU01247/90A patent/YU124790A/xx unknown
- 1990-06-27 DE DE4020475A patent/DE4020475A1/de not_active Withdrawn
- 1990-06-27 RU SU904830539A patent/RU1779253C/ru active
- 1990-06-27 CZ CS903211A patent/CZ281957B6/cs not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH03128374A (ja)	1991-05-31
IT1249001B (it)	1995-02-11
FI92586C (fi)	1994-12-12
CZ281957B6 (cs)	1997-04-16
DE4020475A1 (de)	1991-02-07
RU1779253C (ru)	1992-11-30
US5097031A (en)	1992-03-17
CH680445A5 (fr)	1992-08-31
FR2648815A1 (fr)	1990-12-28
NL9001459A (nl)	1991-01-16
DD295378A5 (de)	1991-10-31
IT9020769A0 (it)	1990-06-26
IT9020769A1 (it)	1991-12-26
YU124790A (en)	1991-10-31
FI903196A0 (fi)	1990-06-26
HU203549B (en)	1991-08-28
CA2019407C (fr)	1997-09-30
CZ321190A3 (en)	1997-01-15
FR2648815B1 (fr)	1992-08-14
FI92586B (fi)	1994-08-31

Similar Documents

Publication	Publication Date	Title
CA2104295A1 (fr)	1992-09-14	Production de gazole par procede d'hydrogenation dans la zone d'alimentation
ATE88453T1 (de)	1993-05-15	Katalytisches einstufenverfahren zur direkten umwandlung von polysacchariden in mehrwertige alkohole.
CA2250734A1 (fr)	1997-10-16	Procede de fabrication d'amines et d'aminonitriles
CA2339311A1 (fr)	1993-02-18	Procede pour preparer des catalyseurs de nickel ameliores pour utilisation dans des reactions d'hydrogenation
MX206481B (en)	2002-02-07	Method of obtaining hydroxyaldehydes
MY115708A (en)	2003-08-30	Processes for producing hydroxyaldehydes
CA2251539A1 (fr)	1997-10-16	Coproduction du 6-aminocapronitrile et de l'hexamethylenediamine
CA2019407A1 (fr)	1990-12-27	Procede d'hydrogenation stereoselectif
CA2039327A1 (fr)	1991-10-01	Preparation de 2-(3-aminopropyl)cycloalcanamines
AU7294087A (en)	1987-11-19	Preparation of diamino-, dibenzylamino- and dialkylamino- benzenediols
MX9603655A (es)	1997-03-29	Procedimiento para la preparacion de pentenaleno.
AU634007B2 (en)	1993-02-11	Process for the preparation of n,n-dimethylamines
AU1749788A (en)	1988-12-22	Process for the selective reduction of 2-quinoxalines-4-oxides
DE69837423D1 (de)	2007-05-10	Verfahren zur herstellung von cyanoarylmethylamin
EP0212287A3 (fr)	1988-08-31	Procédé de production de diamines aliphatiques dimères
EP0295815A3 (fr)	1989-11-15	Procédé de production de 2-quinoxalines
CA2032323A1 (fr)	1991-06-24	Procede de preparation du 2,2-dimethylpropane-1,3-diol
GR3000781T3 (en)	1991-10-10	Process for the preparation of penta-0-acetyl sucrose
NO306669B1 (no)	1999-12-06	FremgangsmÕte for fremstilling av 1,3-alkandioler og 3-hydroksyaldehyder
DE59007103D1 (de)	1994-10-20	Verfahren zur Herstellung von Di-(p-glycidoxicyclohexyl)-methan.
TW363963B (en)	1999-07-11	Carbonylation reaction
AU2749688A (en)	1989-07-06	Process for the preparation of dialkylaminoethylamines
MX9700331A (es)	1997-05-31	Proceso mejorado para r(+)1,2,3,6-tetrahidro-4-fenil-1-[(3-fenil-3-ciclohexen-1-il)metil]pirid ina, un agente del sistema nervioso central.
HUT54978A (en)	1991-04-29	New process for producing thioaniline derivatives
TH25360A (th)	1997-05-29	"การเตรียม อะเซทาลดีไอด์"

Legal Events

Date	Code	Title	Description
1996-08-09	EEER	Examination request
2000-06-20	MKLA	Lapsed