CA2019483A1 - Methodes d'oxydation et de reduction pour la production de 4-acyloxyazetidin-2-one - Google Patents

Methodes d'oxydation et de reduction pour la production de 4-acyloxyazetidin-2-one

Info

Publication number
CA2019483A1
CA2019483A1 CA002019483A CA2019483A CA2019483A1 CA 2019483 A1 CA2019483 A1 CA 2019483A1 CA 002019483 A CA002019483 A CA 002019483A CA 2019483 A CA2019483 A CA 2019483A CA 2019483 A1 CA2019483 A1 CA 2019483A1
Authority
CA
Canada
Prior art keywords
hydrogen
group
acyloxyazetidin
compound
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002019483A
Other languages
English (en)
Inventor
Joseph E. Lynch
Ralph P. Volante
William L. Laswell
Ichiro Shinkai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of CA2019483A1 publication Critical patent/CA2019483A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002019483A 1989-06-21 1990-06-21 Methodes d'oxydation et de reduction pour la production de 4-acyloxyazetidin-2-one Abandoned CA2019483A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US369,396 1989-06-21
US07/369,396 US4923982A (en) 1989-06-21 1989-06-21 Oxidation and reduction method to produce 4-acyloxyazetidin-2-one

Publications (1)

Publication Number Publication Date
CA2019483A1 true CA2019483A1 (fr) 1990-12-21

Family

ID=23455311

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002019483A Abandoned CA2019483A1 (fr) 1989-06-21 1990-06-21 Methodes d'oxydation et de reduction pour la production de 4-acyloxyazetidin-2-one

Country Status (4)

Country Link
US (1) US4923982A (fr)
EP (1) EP0404584A3 (fr)
JP (1) JPH0348681A (fr)
CA (1) CA2019483A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2969387B2 (ja) * 1991-04-18 1999-11-02 高砂香料工業株式会社 置換アセトキシアゼチジノン類及び４−アシルオキシアゼチジノン類の製造方法
EP1256572A1 (fr) * 2001-05-10 2002-11-13 Tessenderlo Chemie S.A. Procédé de déprotection d'azétidones N-substitués
US10087190B1 (en) * 2017-04-24 2018-10-02 Purdue Research Foundation Lactones

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953499A (en) * 1972-12-08 1976-04-27 The Upjohn Company 8,12-Dialkyl-PGE, and PGF1.sub.α
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
JPS6118791A (ja) * 1984-07-05 1986-01-27 Kanegafuchi Chem Ind Co Ltd 新規β−ラクタム化合物及びその製造法
DE3587546D1 (de) * 1984-10-01 1993-09-30 Ciba Geigy Verfahren zur Herstellung von optisch aktiven Acyloxyazetidinonen.
US4791207A (en) * 1985-03-29 1988-12-13 Merck & Co., Inc. Enantioselective process for producing 1-betamethylcarbapenem antibiotic intermediates

Also Published As

Publication number Publication date
EP0404584A3 (fr) 1992-01-02
US4923982A (en) 1990-05-08
JPH0348681A (ja) 1991-03-01
EP0404584A2 (fr) 1990-12-27

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Legal Events

Date Code Title Description
FZDE Discontinued