CA2023954A1 - Procede de resolution optique de l'acide 2-(3-benzoyl) phenylpropionique - Google Patents

Procede de resolution optique de l'acide 2-(3-benzoyl) phenylpropionique

Info

Publication number: CA2023954A1
Authority: CA; Canada
Prior art keywords: group; atom; optical resolution; stands; benzoyl
Prior art date: 1989-10-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

CA2023954A

Other languages

English (en)

Other versions

CA2023954C (fr

Inventor

Hiroyuki Nohira

Kazutaka Arai

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Nagase and Co Ltd

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-10-17

Filing date

1990-08-24

Publication date

1991-04-18

1989-10-17 Priority claimed from JP26946689A external-priority patent/JP2859657B2/ja

1990-08-24 Application filed by Individual filed Critical Individual

1991-04-18 Publication of CA2023954A1 publication Critical patent/CA2023954A1/fr

1999-05-04 Application granted granted Critical

1999-05-04 Publication of CA2023954C publication Critical patent/CA2023954C/fr

2010-08-24 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

230000003287 optical effect Effects 0.000 title abstract 3
XMIIGOLPHOKFCH-UHFFFAOYSA-N 3-phenylpropionic acid Chemical compound OC(=O)CCC1=CC=CC=C1 XMIIGOLPHOKFCH-UHFFFAOYSA-N 0.000 title 1
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
229910052801 chlorine Inorganic materials 0.000 abstract 2
125000001309 chloro group Chemical group Cl* 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CA002023954A 1989-10-17 1990-08-24 Procede de resolution optique de l'acide 2-(3-benzoyl) phenylpropionique Expired - Fee Related CA2023954C (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1-269466		1989-10-17
JP26946689A JP2859657B2 (ja)	1989-02-27	1989-10-17	（±）―２―（３―ベンゾイル）フェニルプロピオン酸の光学分割法

Publications (2)

Publication Number	Publication Date
CA2023954A1 true CA2023954A1 (fr)	1991-04-18
CA2023954C CA2023954C (fr)	1999-05-04

Family

ID=17472828

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002023954A Expired - Fee Related CA2023954C (fr)	1989-10-17	1990-08-24	Procede de resolution optique de l'acide 2-(3-benzoyl) phenylpropionique

Country Status (3)

Country	Link
US (1)	US5191112A (fr)
EP (1)	EP0423467A3 (fr)
CA (1)	CA2023954C (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69206306T2 (de) *	1991-04-08	1996-06-13	Sumitomo Chemical Co	Optisch aktive Sekundär-Aminverbindung, Verfahren zur Herstellung einer optisch aktiven Sekundär-Aminverbindung und Verfahren zur Herstellung optisch aktiver Carbonsäure durch die Verwendung dieser Verbindung.
CA2074932A1 (fr) *	1991-08-23	1993-02-24	Hiroyuki Nohira	Resolution optique de l'acide (+)-2-(4-isobutylphenyl) propionique
ES2061403B1 (es) *	1993-04-16	1995-06-16	Medichem Sa	Procedimiento de obtencion del acido d-(-) -3 acetiltio-2- metilpropionico.
JPH08151344A (ja) *	1994-09-26	1996-06-11	Nagase & Co Ltd	２−（３−ベンゾイルフェニル）プロピオン酸の光学分割方法
US5677469A (en) *	1995-05-18	1997-10-14	Sepracor, Inc.	Process for resolving chiral acids with 1-aminoindan-2-ols
IN183408B (fr) *	1996-11-20	1999-12-25	Kuraray Co
DE19717429A1 (de) *	1997-04-25	1998-12-24	Bayer Ag	Herstellung enantiomerenreiner Biarylketocarbonsäuren
JP4126921B2 (ja) *	2002-02-15	2008-07-30	味の素株式会社	光学活性なβ−フェニルアラニン誘導体の製造方法
ITMI20061297A1 (it) *	2006-07-04	2008-01-05	Laboratorio Chimico Int Spa	Procedimento per la preparazione della'acido (r)-(-)-3-(carbamoilmetil)-5-metilesanoico e del pregabalin e intermedi di sintesi

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1546478A (fr) *	1967-01-27	1968-11-22	Rhone Poulenc Sa	Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation
CA1007643A (en) *	1972-10-24	1977-03-29	Janssen Pharmaceutica Naamloze Vennootschap	Aroyl-substituted phenylacetic acid derivatives
DK268779A (da) *	1978-07-03	1980-01-04	Lilly Co Eli	Fremgangsmaade til fremstilling af phenethanolaminer
JPS57171938A (en) *	1981-04-15	1982-10-22	Nissan Chem Ind Ltd	Preparation of optically active naphthylpropionic acid ester
IT1203605B (it) *	1985-04-18	1989-02-15	Alfa Chem Ital	Processo per la risoluzione ottica di miscigli racemi di acidi e naftilpropionici
JPH0684332B2 (ja) *	1985-06-20	1994-10-26	住友化学工業株式会社	ａ−イソプロピル−ｐ−クロルフエニル酢酸の光学分割法
IT1222013B (it) *	1987-07-10	1990-08-31	Chimica Profarmaco Spa Ind	Processo di risoluzione ottica di acido 2 (6 metossi 2 naftil) propionico
DE3814887C1 (fr) *	1988-05-02	1989-09-21	Medice Chem.-Pharm. Fabrik Puetter Gmbh & Co Kg, 5860 Iserlohn, De
DE3824353A1 (de) *	1988-07-19	1990-01-25	Paz Arzneimittelentwicklung	Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren

1990
- 1990-08-24 US US07/571,871 patent/US5191112A/en not_active Expired - Fee Related
- 1990-08-24 CA CA002023954A patent/CA2023954C/fr not_active Expired - Fee Related
- 1990-08-27 EP EP19900116382 patent/EP0423467A3/en not_active Withdrawn

Also Published As

Publication number	Publication date
CA2023954C (fr)	1999-05-04
US5191112A (en)	1993-03-02
EP0423467A3 (en)	1992-06-03
EP0423467A2 (fr)	1991-04-24

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Legal Events

Date	Code	Title	Description
1992-04-09	EEER	Examination request
2000-08-24	MKLA	Lapsed