CA2059632A1 - Reveromycine a, methode d'obtention et agent antitumoral ainsi qu'agent antifongique en contenant - Google Patents

Reveromycine a, methode d'obtention et agent antitumoral ainsi qu'agent antifongique en contenant

Info

Publication number
CA2059632A1
CA2059632A1 CA2059632A CA2059632A CA2059632A1 CA 2059632 A1 CA2059632 A1 CA 2059632A1 CA 2059632 A CA2059632 A CA 2059632A CA 2059632 A CA2059632 A CA 2059632A CA 2059632 A1 CA2059632 A1 CA 2059632A1
Authority
CA
Canada
Prior art keywords
same
reveromycin
agent
antibiotic
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2059632A
Other languages
English (en)
Other versions
CA2059632C (fr
Inventor
Kiyoshi Isono
Hiroyuki Osada
Hidetoshi Takahashi
Gosei Kawanishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
RIKEN
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2059632A1 publication Critical patent/CA2059632A1/fr
Application granted granted Critical
Publication of CA2059632C publication Critical patent/CA2059632C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
CA002059632A 1990-06-14 1991-06-07 Reveromycine a, methode d'obtention et agent antitumoral ainsi qu'agent antifongique en contenant Expired - Lifetime CA2059632C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2155816A JPH0633271B2 (ja) 1990-06-14 1990-06-14 リベロマイシンａ、その製造法並びに抗腫瘍剤及び抗真菌剤
JP155816/1990 1990-06-14

Publications (2)

Publication Number Publication Date
CA2059632A1 true CA2059632A1 (fr) 1991-12-15
CA2059632C CA2059632C (fr) 1996-09-03

Family

ID=15614106

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002059632A Expired - Lifetime CA2059632C (fr) 1990-06-14 1991-06-07 Reveromycine a, methode d'obtention et agent antitumoral ainsi qu'agent antifongique en contenant

Country Status (6)

Country Link
US (1) US5322854A (fr)
EP (1) EP0491956B1 (fr)
JP (1) JPH0633271B2 (fr)
CA (1) CA2059632C (fr)
DE (1) DE69114252T2 (fr)
WO (1) WO1991019718A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994020503A1 (fr) * 1993-03-08 1994-09-15 Institut Francais De Recherche Scientifique Pour Le Developpement En Cooperation (Orstom) Bistramides biologiquement actifs, leur obtention et leurs applications en therapeutique
FR2707644B1 (fr) * 1993-06-29 1995-09-29 Orstom Bistramides biologiquement actifs, leur préparation et leurs applications biologiques.
US6335364B1 (en) * 1998-06-29 2002-01-01 Parker Hughes Institute Synthetic spiroketal pyranes as potent anti-cancer agents
AU4845499A (en) * 1998-06-29 2000-01-17 Parker Hughes Institute Synthetic spiroketal pyranes as potent anti-cancer agents
US6734207B2 (en) 2001-04-20 2004-05-11 Parker Hughes Institute Cytotoxic compounds
KR100634874B1 (ko) 2004-08-20 2006-10-16 충남대학교산학협력단 신규 미생물 스트렙토마이세스 에스피 ｓｈ09 및 이를이용한 흰가루병을 포함하는 식물진균병 방제방법
EP2615168B1 (fr) * 2010-08-31 2017-07-19 Riken Procédé de production de révéromycine a ou de son intermédiaire de synthèse, procédé de production de composés contenant un cycle spirocétal et nouveaux antinéoplasiques, fongicides et agents thérapeutiques destinés aux troubles osseux

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032184A (ja) * 1987-12-24 1991-01-08 Nippon Kayaku Co Ltd 新規抗生物質ｎｋ８６―０２７９、その製法及びその用途

Also Published As

Publication number Publication date
JPH0449296A (ja) 1992-02-18
EP0491956A1 (fr) 1992-07-01
JPH0633271B2 (ja) 1994-05-02
EP0491956A4 (en) 1992-07-22
DE69114252D1 (de) 1995-12-07
DE69114252T2 (de) 1996-04-11
EP0491956B1 (fr) 1995-11-02
US5322854A (en) 1994-06-21
CA2059632C (fr) 1996-09-03
WO1991019718A1 (fr) 1991-12-26

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKEC Expiry (correction)
MKEC Expiry (correction)

Effective date: 20121202