CA2069106A1 - Proteines chimeriques - Google Patents

Proteines chimeriques

Info

Publication number
CA2069106A1
CA2069106A1 CA002069106A CA2069106A CA2069106A1 CA 2069106 A1 CA2069106 A1 CA 2069106A1 CA 002069106 A CA002069106 A CA 002069106A CA 2069106 A CA2069106 A CA 2069106A CA 2069106 A1 CA2069106 A1 CA 2069106A1
Authority
CA
Canada
Prior art keywords
peptide
protein
subunit
epitope region
ctb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002069106A
Other languages
English (en)
Inventor
Mark T. Dertzbaugh
Francis L. Macrina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Innovation Partnership Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2069106A1 publication Critical patent/CA2069106A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA002069106A 1989-11-29 1990-11-28 Proteines chimeriques Abandoned CA2069106A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44278389A 1989-11-29 1989-11-29
US442,783 1989-11-29

Publications (1)

Publication Number Publication Date
CA2069106A1 true CA2069106A1 (fr) 1991-05-30

Family

ID=23758123

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002069106A Abandoned CA2069106A1 (fr) 1989-11-29 1990-11-28 Proteines chimeriques

Country Status (5)

Country Link
EP (1) EP0502099A4 (fr)
JP (1) JPH05503420A (fr)
CA (1) CA2069106A1 (fr)
IL (1) IL96475A0 (fr)
WO (1) WO1991007979A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6043057A (en) * 1988-09-16 2000-03-28 Vitec Aktiebolag Recombinant systems for expression of the cholera B-sub-unit with the aid of foreign promoters and/or leader peptides
JPH07506374A (ja) * 1992-05-01 1995-07-13 フォーシス デンタル インファーマリー フォー チルドレン う蝕予防用合成ペプチドワクチン
US5681571A (en) * 1993-10-08 1997-10-28 Duotol Ab Immunological tolerance-inducing agent
GB9409387D0 (en) * 1994-05-11 1994-06-29 Unilever Plc Glucan-binding domains (gbp's) and hybird proteins containing gbd's as novel active systems targeted to dental plaque
EP0792365A1 (fr) * 1994-11-17 1997-09-03 Maxim Pharmaceuticals Immunogenes pour stimuler l'immunite des muqueuses
US5876727A (en) * 1995-03-31 1999-03-02 Immulogic Pharmaceutical Corporation Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
US6287566B1 (en) * 1995-05-19 2001-09-11 The United States Of America As Represented By The Secretary Of The Army Protective peptides neurotoxin of C. botulinum
AU6505796A (en) * 1995-07-26 1997-02-26 Maxim Pharmaceuticals Mucosal delivery of polynucleotides
US6036953A (en) * 1996-11-29 2000-03-14 The General Hospital Corporation Heterologous antigens in live cell V. cholerae strains
US7390619B1 (en) 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
CA2320960A1 (fr) * 1998-02-11 1999-08-19 Maxygen, Inc. Optimisation des proprietes immunomodulatrices des vaccins genetiques
ATE364395T1 (de) 1998-04-10 2007-07-15 Andrew Lees Konjugat-impfstoffe zur vorbeugung der zahnkaries
DE102011111688A1 (de) * 2011-08-24 2013-02-28 Bioserv Analytik Und Medizinprodukte Gmbh Verfahren zur schnellen Isolation bzw. Aufreinigung von rekombinanten Proteinen mit einer (nicht toxischen) Choleratoxin-Domäne

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56169215A (en) * 1980-05-28 1981-12-25 Tdk Corp Magnetic erasing head and its manufacture
FR2604021B1 (fr) * 1986-09-17 1988-10-28 Commissariat Energie Atomique Procede de realisation de tetes magnetiques en couches minces et a structure planaire et tete obtenue par ce procede
FR2636842B1 (fr) * 1988-09-27 1994-06-10 Liege Universite Etat Proteine de fusion d'une sequence derivee de la sous-unite b de la toxine cholerique et d'un antigene heterologue doue de proprietes immunogenes, compositions de vaccins les contenant et acides nucleiques recombinants contenant une sequence de nucleotides codant pour ladite proteine de fusion

Also Published As

Publication number Publication date
IL96475A0 (en) 1991-08-16
JPH05503420A (ja) 1993-06-10
WO1991007979A1 (fr) 1991-06-13
EP0502099A4 (en) 1993-02-17
EP0502099A1 (fr) 1992-09-09

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Legal Events

Date Code Title Description
FZDE Discontinued