CA2082059A1 - Nouveaux analogues synthetiques de la somatostatine - Google Patents

Nouveaux analogues synthetiques de la somatostatine

Info

Publication number
CA2082059A1
CA2082059A1 CA002082059A CA2082059A CA2082059A1 CA 2082059 A1 CA2082059 A1 CA 2082059A1 CA 002082059 A CA002082059 A CA 002082059A CA 2082059 A CA2082059 A CA 2082059A CA 2082059 A1 CA2082059 A1 CA 2082059A1
Authority
CA
Canada
Prior art keywords
peptide
ala
leu
composition
grf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002082059A
Other languages
English (en)
Inventor
David H. Coy
William Murphy
Simon J. Hocart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2082059A1 publication Critical patent/CA2082059A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Luminescent Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
CA002082059A 1990-05-04 1991-04-30 Nouveaux analogues synthetiques de la somatostatine Abandoned CA2082059A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51905490A 1990-05-04 1990-05-04
US519,054 1990-05-04

Publications (1)

Publication Number Publication Date
CA2082059A1 true CA2082059A1 (fr) 1991-11-05

Family

ID=24066591

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002082059A Abandoned CA2082059A1 (fr) 1990-05-04 1991-04-30 Nouveaux analogues synthetiques de la somatostatine

Country Status (5)

Country Link
EP (1) EP0527914A4 (fr)
JP (1) JPH06502618A (fr)
AU (1) AU651976B2 (fr)
CA (1) CA2082059A1 (fr)
WO (1) WO1991016923A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI
WO1994011397A1 (fr) * 1992-11-13 1994-05-26 The Administrators Of The Tulane Educational Fund Agonistes de somatostatine
AU5668894A (en) * 1992-11-13 1994-06-08 The Administrators Of The Tulane Eductional Fund Ghrh agonists
US5550212A (en) * 1993-12-17 1996-08-27 The Administrators Of The Tulane Educational Fund Analogues of hGH-RH(1-29)NH2 having antagonistic activity
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide
CA2158782C (fr) * 1994-09-23 2010-01-12 Pierrette Gaudreau Marqueur pour recepteurs de facteurs liberant des hormones de croissance
EP0820296A4 (fr) * 1995-04-14 1999-06-30 Univ Tulane Analogues du facteur liberant l'hormone de croissance
US6458764B1 (en) * 1995-05-26 2002-10-01 Theratechnologies Inc. GRF analogs with increased biological potency
US5942489A (en) * 1996-05-03 1999-08-24 The Administrators Of The Tulane Educational Fund HGH-RH(1-29)NH2 analogues having antagonistic activity
US6057422A (en) * 1998-11-25 2000-05-02 The Administrators Of The Tulane Educational Fund Antagonistic analogs of GH-RH inhibiting IGF-I and -II
CA2718146C (fr) * 2008-03-28 2016-09-20 The University Of Miami Nouveaux analogues antagonistes substitues n- et c-terminaux de gh-rh
US8691942B2 (en) 2008-03-28 2014-04-08 University Of Miami N- and C- terminal substituted antagonistic analogs of GH-RH
CA2727082C (fr) 2008-06-12 2019-02-26 Syntaxin Limited Proteines de fusion destinees a la suppression de l'acromegalie
CN102083451A (zh) 2008-06-12 2011-06-01 赛恩泰新公司 癌症的抑制
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
CA3129405A1 (fr) 2019-02-08 2020-08-13 United States Government As Represented By The Department Of Veterans Affairs Antagonistes d'hormone de liberation d'hormone de croissance et leurs utilisations
CN114126653B (zh) 2019-07-18 2024-02-20 迈阿密大学 用于治疗结节病的方法的ghrh拮抗剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
IL86102A (en) * 1987-05-11 1994-04-12 Univ Tulane Alkylated growth hormone-releasing peptides and use thereof
US5262519A (en) * 1991-05-15 1993-11-16 The Salk Institute For Biological Studies GRF analogs XI

Also Published As

Publication number Publication date
JPH06502618A (ja) 1994-03-24
EP0527914A1 (fr) 1993-02-24
AU7882291A (en) 1991-11-27
WO1991016923A1 (fr) 1991-11-14
EP0527914A4 (en) 1993-08-11
AU651976B2 (en) 1994-08-11

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Legal Events

Date Code Title Description
FZDE Dead