CA2093521A1 - Detection de toxines diarrheogenes provenant des mollusques - Google Patents

Detection de toxines diarrheogenes provenant des mollusques

Info

Publication number
CA2093521A1
CA2093521A1 CA2093521A CA2093521A CA2093521A1 CA 2093521 A1 CA2093521 A1 CA 2093521A1 CA 2093521 A CA2093521 A CA 2093521A CA 2093521 A CA2093521 A CA 2093521A CA 2093521 A1 CA2093521 A1 CA 2093521A1
Authority
CA
Canada
Prior art keywords
antibody
diarrheogenic
detection
dinophysistoxin
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2093521A
Other languages
English (en)
Other versions
CA2093521C (fr
Inventor
Shiro Matsuura
Yutaka Takagaki
Yonekazu Hamano
Ken Fukushi
Keigo Kabasawa
Hiroshi Kita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSAKAFU
LSI Medience Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2093521A1 publication Critical patent/CA2093521A1/fr
Application granted granted Critical
Publication of CA2093521C publication Critical patent/CA2093521C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention se rapporte à un dosage immunologique de composés solubles dans les graisses, qui consiste à effectuer une réaction antigénique-anticorpal en présence d'un solvant organique en utilisant un anticorps qui résiste aux solvants organiques. Ce procédé permet de procéder à la réaction antigénique-anticorpal du composé soluble dans les graisses avec l'anticorps, en utilisant un extrait d'un spécimen avec un solvant organique, et il sert à simplifier l'opération. L'invention se rapporte également à un anticorps monoclonal spécifique au moins de l'acide okadaïque, de la dinophysistoxine (1) et de la dinophysistoxine (3); à un hybridome qui produit cet anticorps; et à un procédé pour détecter par voie immunologique les poisons de crustacés diarrhéogènes, en utilisant cet anticorps. L'invention permet de détecter spécifiquement chacun de ces trois poisons de crustacés diarrhéogènes.
CA002093521A 1991-08-09 1992-08-10 Detection de toxines diarrheogenes provenant des mollusques Expired - Lifetime CA2093521C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP3-224864 1991-08-09
JP22486491 1991-08-09
JP3-306859 1991-10-26
JP30685991 1991-10-26
PCT/JP1992/001021 WO1993003365A1 (fr) 1991-08-09 1992-08-10 Dosage immunologique, anticorps monoclonal et hybridome

Publications (2)

Publication Number Publication Date
CA2093521A1 true CA2093521A1 (fr) 1993-02-10
CA2093521C CA2093521C (fr) 2000-02-22

Family

ID=26526301

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002093521A Expired - Lifetime CA2093521C (fr) 1991-08-09 1992-08-10 Detection de toxines diarrheogenes provenant des mollusques

Country Status (7)

Country Link
US (1) US5525476A (fr)
EP (1) EP0554458B1 (fr)
JP (1) JP3154724B2 (fr)
CA (1) CA2093521C (fr)
DE (1) DE69228739T2 (fr)
FI (1) FI113205B (fr)
WO (1) WO1993003365A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3414856B2 (ja) 1994-08-09 2003-06-09 株式会社ヤトロン ジフェニルエーテル化合物の免疫学的測定方法
WO1999040437A1 (fr) * 1998-02-06 1999-08-12 Dexall Biomedical Labs, Inc. Procedes et appareils ameliores d'analyse de reactifs immunitaires dans des liquides biologiques
GB9824772D0 (en) * 1998-11-11 1999-01-06 Skeland Stein O D Assay
IT1318605B1 (it) * 2000-06-30 2003-08-27 Uni Degli Studi Di Modena E Re Procedimoento per il dosaggio di tossine dsp del gruppo delledinophysitossine e delle yessottossine.
US8022188B2 (en) * 2006-04-24 2011-09-20 Abbott Laboratories Immunosuppressant binding antibodies and methods of obtaining and using same
WO2009067521A1 (fr) * 2007-11-19 2009-05-28 Florida Atlantic University Puces microfluidiques et systèmes d'analyse d'une expression de protéine, et leurs procédés d'utilisation
RU2666247C1 (ru) * 2017-11-21 2018-09-06 Федеральное Государственное Бюджетное Учреждение "Федеральный Исследовательский Центр Питания, Биотехнологии И Безопасности Пищи" Способ количественного определения окадаиковой кислоты в морепродуктах

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5711986A (en) * 1980-06-25 1982-01-21 Fujisawa Pharmaceut Co Ltd Okadaic acid, its salt, and its ester
JPS5710453A (en) * 1981-04-16 1982-01-20 Toyo Jozo Co Ltd Method for improving immunity determination
CA1302920C (fr) * 1987-10-09 1992-06-09 Taizo Uda Anticorps monoclonal des acides akadaiques, procede pour la production de cet anticorps, reactif pour le test des acides akadaiques a l'aide de l'anticorps en question, et methodede test
JPH0196199A (ja) * 1987-10-09 1989-04-14 Ube Ind Ltd オカダ酸群に対するモノクローナル抗体およびそのモノクローナル抗体の製法
JPH01156666A (ja) * 1987-12-15 1989-06-20 Ube Ind Ltd オカダ酸群の測定試薬及び測定法
JPH02171187A (ja) * 1988-12-23 1990-07-02 Meidensha Corp 酵素の活性維持方法
WO1991005875A1 (fr) * 1989-10-23 1991-05-02 Hawaii Biotechnology Group, Inc. Analyses des proteines liantes specifiques dans un solvant non aqueux
US5180665A (en) * 1990-11-21 1993-01-19 Her Majesty The Queen In Right Of Canada, As Represented By The National Research Council Of Canada Method for quantitatively assaying the presence of diarrhetic shellfish poisoning toxins in marine samples
US5206141A (en) * 1991-09-24 1993-04-27 Hawaii Chemtect International Okadaic acid testing for ciguatoxin

Also Published As

Publication number Publication date
FI931581A7 (fi) 1993-05-25
FI931581A0 (fi) 1993-04-07
FI113205B (fi) 2004-03-15
CA2093521C (fr) 2000-02-22
EP0554458B1 (fr) 1999-03-24
US5525476A (en) 1996-06-11
JP3154724B2 (ja) 2001-04-09
DE69228739T2 (de) 1999-09-02
EP0554458A1 (fr) 1993-08-11
WO1993003365A1 (fr) 1993-02-18
EP0554458A4 (en) 1994-08-24
DE69228739D1 (de) 1999-04-29

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Legal Events

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MKEX Expiry
MKEX Expiry

Effective date: 20120810