CA2099433A1 - Amelioration des signaux dans les immuno-essais faisant appel a des microparticules contenant differentes substances detectables - Google Patents

Amelioration des signaux dans les immuno-essais faisant appel a des microparticules contenant differentes substances detectables

Info

Publication number
CA2099433A1
CA2099433A1 CA2099433A CA2099433A CA2099433A1 CA 2099433 A1 CA2099433 A1 CA 2099433A1 CA 2099433 A CA2099433 A CA 2099433A CA 2099433 A CA2099433 A CA 2099433A CA 2099433 A1 CA2099433 A1 CA 2099433A1
Authority
CA
Canada
Prior art keywords
detectable substances
immunoassays
microparticles
enhancement
signal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2099433A
Other languages
English (en)
Other versions
CA2099433C (fr
Inventor
Thomas Joseph Mercolino
Joanne Haller Hasskamp
Edward Charles Mcfarland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2099433A1 publication Critical patent/CA2099433A1/fr
Application granted granted Critical
Publication of CA2099433C publication Critical patent/CA2099433C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/586—Liposomes, microcapsules or cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/973—Simultaneous determination of more than one analyte
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002099433A 1992-07-02 1993-06-30 Amelioration des signaux dans les immuno-essais faisant appel a des microparticules contenant differentes substances detectables Expired - Fee Related CA2099433C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/908,136 1992-07-02
US07/908,136 US5369036A (en) 1992-07-02 1992-07-02 Enhancement of signal in immunoassays using microparticles which contain different detectable substances

Publications (2)

Publication Number Publication Date
CA2099433A1 true CA2099433A1 (fr) 1994-01-03
CA2099433C CA2099433C (fr) 1999-10-12

Family

ID=25425258

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002099433A Expired - Fee Related CA2099433C (fr) 1992-07-02 1993-06-30 Amelioration des signaux dans les immuno-essais faisant appel a des microparticules contenant differentes substances detectables

Country Status (6)

Country Link
US (1) US5369036A (fr)
EP (1) EP0577092B1 (fr)
JP (2) JP2643775B2 (fr)
AU (1) AU668171B2 (fr)
CA (1) CA2099433C (fr)
DE (1) DE69329318T2 (fr)

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WO1994026299A1 (fr) * 1993-05-13 1994-11-24 Becton Dickinson And Company Liposomes contenant des milieux de densite
FR2707658B1 (fr) * 1993-07-12 1995-11-24 Prolabo Sa Latex fluorescent comportant au moins deux fluorochromes, procédé d'obtention et application dudit latex comme marqueur, notamment en biologie.
GB9326379D0 (en) * 1993-12-23 1994-02-23 Sinvent As Method of assay
US5750357A (en) * 1994-05-18 1998-05-12 Microquest Diagnostics, Inc. Method of rapid analyte detection
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US5840859A (en) * 1995-07-06 1998-11-24 Research Corporation Technologies, Inc. (Aminostyryl)pyridinium compounds for radiolabelling cell membranes
IL117605A0 (en) * 1996-03-21 1996-07-23 Markman Ofer Multi-antigen serological diagnosis
GB9801120D0 (en) * 1998-01-21 1998-03-18 Secr Defence Detection system
IL141759A0 (en) * 1998-09-03 2002-03-10 Trellis Bioinformatics Inc Multihued labels
US6642062B2 (en) * 1998-09-03 2003-11-04 Trellis Bioinformatics, Inc. Multihued labels
CA2360927C (fr) * 1999-01-23 2018-03-06 Minerva Biotechnologies Corporation Interaction entre des especes immobilisees sur des colloides et des especes existant sur des structures colloidales
US20050148101A1 (en) * 1999-01-23 2005-07-07 Bamdad Cynthia C. Interaction of colloid-immobilized species with species on non-colloidal structures
ATE273516T1 (de) * 1999-06-23 2004-08-15 Cornell Res Foundation Inc Entwässerung/rehydratisierung von markierten liposomen auf einer prüfeinrichtung
US6576460B1 (en) 1999-10-28 2003-06-10 Cornell Research Foundation, Inc. Filtration-detection device and method of use
CA2413884A1 (fr) * 2000-06-23 2002-01-03 Minerva Biotechnologies Corporation Detection rapide et sensible de l'agregation des proteines
JP2004512497A (ja) * 2000-06-23 2004-04-22 ミナーヴァ・バイオテクノロジーズ・コーポレーション コロイドが固定された種と非コロイド構造上の種との相互作用
DE10042023C2 (de) * 2000-08-08 2003-04-10 Biognostic Ag Kapseln, die feste Teilchen signalerzeugender Substanzen einkapseln, und deren Verwendung bei Bioassays zum Nachweis von Zielmolekülen in einer Probe
AU2001295442A1 (en) * 2000-10-17 2002-04-29 Besst-Test Aps Assay for directly detecting an inflammatory indicator in a body fluid sample
US6797481B1 (en) 2000-10-17 2004-09-28 Dade Behring Marburg Gmbh Simultaneous screening of multiple analytes
AU1038402A (en) 2000-10-17 2002-04-29 Besst Test Aps Assay for directly detecting a rs virus related biological cell in a body fluid sample
JP2004511808A (ja) * 2000-10-17 2004-04-15 ベッスト−テスト　アンパーツゼルスカブ 体液サンプル中の生物学的細胞の直接的検出のためのアッセイ
RU2203495C2 (ru) * 2001-06-06 2003-04-27 Государственный научно-исследовательский институт биологического приборостроения Способ липосомального иммуноанализа для детектирования аналитов в образце
GB0129776D0 (en) * 2001-12-13 2002-01-30 Sec Dep For Environment Food & Assay device and method
WO2003064679A2 (fr) * 2002-01-30 2003-08-07 Id Biomedical Corporation Procedes pour detecter des microorganismes resistant a la vancomycine et composition pour la mise en oeuvre dudit procede
RU2213974C1 (ru) * 2002-04-09 2003-10-10 Баженов Алексей Иванович Способ одновременного определения нескольких аналитов
ATE478337T1 (de) 2002-05-31 2010-09-15 Cornell Res Foundation Inc Methoden zum nachweis analyten in proben
US20050019954A1 (en) * 2003-07-23 2005-01-27 Eastman Kodak Company Photochromic dyes for microsphere based sensor
US7413868B2 (en) 2003-11-05 2008-08-19 Trellis Bioscience, Inc. Use of particulate labels in bioanalyte detection methods
JP4347107B2 (ja) 2004-03-26 2009-10-21 株式会社イノアックコーポレーション 磁気的免疫反応測定のための試験容器およびその製造方法
WO2005124348A1 (fr) * 2004-06-09 2005-12-29 Becton, Dickinson And Company Detecteur d'analytes multiples
EP1787124A2 (fr) 2004-06-23 2007-05-23 The University Of Texas System Procedes et compositions pour la detection de molecules biologiques faisant appel a un complexe de deux particules
WO2006115870A2 (fr) * 2005-04-20 2006-11-02 Becton Dickinson And Company Systeme de microparticules multiplex
GB0512769D0 (en) * 2005-06-23 2005-07-27 Avacta Ltd Ratiometic multicolour fluorescence correlation screening; agents for use therewith and methods of production thereof
JP2007101339A (ja) * 2005-10-04 2007-04-19 Naoyoshi Egashira 電解発光物質を内包するリポソームによるイムノアッセイ方法
EP1982183B9 (fr) 2006-01-19 2012-12-12 Lattec I/S Bandelette d'analyse et procede pour determiner une substance a analyser dans un echantillon
CA2637705C (fr) 2006-01-19 2013-10-29 Lattec I/S Nouvelle construction d'un dispositif de baton sec et procede pour determiner une substance a analyser dans un echantillon utilisant ledit dispositif de baton sec
PL2271938T3 (pl) 2008-04-11 2014-07-31 Univ Texas Sposób i urządzenie do wzmacniania elektrogenerowanej chemiluminescencji nanocząsteczek
DE102008019928A1 (de) * 2008-04-21 2009-12-31 Siemens Healthcare Diagnostics Gmbh Polyelektrolyt-Monoschichten mit kovalenten Bindungsstellen für optische Signalwandler
AU2009244904B2 (en) 2008-05-08 2014-04-17 Board Of Regents Of The University Of Texas System Luminescent nanostructured materials for use in electrogenerated chemiluminescence
US20110076697A1 (en) * 2009-04-28 2011-03-31 Innovative Laboratory Technologies, Inc. Lateral-flow immuno-chromatographic assay devices
RU2497128C2 (ru) * 2011-12-30 2013-10-27 Федеральное Государственное Автономное Образовательное Учреждение Высшего Профессионального Образования "Сибирский Федеральный Университет" Способ одновременного определения двух аналитов биолюминесцентным молекулярным микроанализом
GB201705407D0 (en) 2017-04-04 2017-05-17 Imp Innovations Ltd Colour changing compositions

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US4703017C1 (en) * 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
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JPS6345563A (ja) * 1986-04-11 1988-02-26 Hitachi Ltd 細胞分析方法
US4920046A (en) * 1987-02-20 1990-04-24 Becton, Dickinson And Company Process, test device, and test kit for a rapid assay having a visible readout
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GB9003593D0 (en) * 1990-02-16 1990-04-11 Pa Consulting Services Improvements in or relating to fluorescence assays
JP2683172B2 (ja) * 1991-10-01 1997-11-26 キヤノン株式会社 検体測定方法及び検体測定装置
ATE184399T1 (de) * 1991-12-13 1999-09-15 Bion Diagnostic Sciences Inc Agglutierungsassays und kolloide farbstoffe verwendende testsätze

Also Published As

Publication number Publication date
US5369036A (en) 1994-11-29
DE69329318T2 (de) 2001-04-26
JP2643775B2 (ja) 1997-08-20
JPH07287016A (ja) 1995-10-31
EP0577092B1 (fr) 2000-08-30
EP0577092A3 (en) 1994-09-07
EP0577092A2 (fr) 1994-01-05
JPH09184841A (ja) 1997-07-15
AU668171B2 (en) 1996-04-26
CA2099433C (fr) 1999-10-12
DE69329318D1 (de) 2000-10-05
AU4144093A (en) 1994-01-06

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