CA2101152C - Mass spectrometry method using supplemental ac voltage signals - Google Patents

Mass spectrometry method using supplemental ac voltage signals

Info

Publication number: CA2101152C
Authority: CA; Canada
Prior art keywords: voltage signal; ions; daughter; frequency; supplemental
Prior art date: 1991-02-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

CA002101152A

Other languages

English (en)

French (fr)

Other versions

CA2101152A1 (en

Inventor

Paul E. Kelley

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Shimadzu Corp

Original Assignee

Shimadzu Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-02-28

Filing date

1992-02-11

Publication date

1999-03-30

1992-02-11 Application filed by Shimadzu Corp filed Critical Shimadzu Corp

1992-08-29 Publication of CA2101152A1 publication Critical patent/CA2101152A1/en

1999-03-30 Application granted granted Critical

1999-03-30 Publication of CA2101152C publication Critical patent/CA2101152C/en

2012-02-11 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

230000000153 supplemental effect Effects 0.000 title claims abstract description 234
238000000034 method Methods 0.000 title claims abstract description 58
238000004949 mass spectrometry Methods 0.000 title claims description 21
150000002500 ions Chemical class 0.000 claims abstract description 410
238000001514 detection method Methods 0.000 claims abstract description 60
238000010494 dissociation reaction Methods 0.000 claims abstract description 51
230000005593 dissociations Effects 0.000 claims abstract description 51
230000007935 neutral effect Effects 0.000 claims description 23
238000005040 ion trap Methods 0.000 abstract description 8
230000008569 process Effects 0.000 abstract description 3
238000010894 electron beam technology Methods 0.000 description 12
230000003213 activating effect Effects 0.000 description 9
238000003860 storage Methods 0.000 description 7
230000004044 response Effects 0.000 description 6
101150085091 lat-2 gene Proteins 0.000 description 5
230000008859 change Effects 0.000 description 4
238000010586 diagram Methods 0.000 description 4
238000004519 manufacturing process Methods 0.000 description 4
238000004885 tandem mass spectrometry Methods 0.000 description 4
230000003993 interaction Effects 0.000 description 3
238000009738 saturating Methods 0.000 description 3
ODINCKMPIJJUCX-UHFFFAOYSA-N Calcium oxide Chemical compound [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
230000008878 coupling Effects 0.000 description 1
238000010168 coupling process Methods 0.000 description 1
238000005859 coupling reaction Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000000463 material Substances 0.000 description 1
230000003340 mental effect Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
238000010408 sweeping Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
- H01J49/0063—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by applying a resonant excitation voltage
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/424—Three-dimensional ion traps, i.e. comprising end-cap and ring electrodes
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/426—Methods for controlling ions
- H01J49/427—Ejection and selection methods
- H01J49/4285—Applying a resonant signal, e.g. selective resonant ejection matching the secular frequency of ions

Landscapes

Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Electron Tubes For Measurement (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

CA002101152A 1991-02-28 1992-02-11 Mass spectrometry method using supplemental ac voltage signals Expired - Lifetime CA2101152C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US66219191A	1991-02-28	1991-02-28
US662,191		1991-02-28

Publications (2)

Publication Number	Publication Date
CA2101152A1 CA2101152A1 (en)	1992-08-29
CA2101152C true CA2101152C (en)	1999-03-30

Family

ID=24656746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002101152A Expired - Lifetime CA2101152C (en)	1991-02-28	1992-02-11	Mass spectrometry method using supplemental ac voltage signals

Country Status (8)

Country	Link
EP (1)	EP0573579B1 (de)
JP (1)	JP2743034B2 (de)
AT (1)	ATE151915T1 (de)
CA (1)	CA2101152C (de)
DE (1)	DE69219113T2 (de)
DK (1)	DK0573579T3 (de)
ES (1)	ES2106177T3 (de)
WO (1)	WO1992015392A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5200613A (en) *	1991-02-28	1993-04-06	Teledyne Mec	Mass spectrometry method using supplemental AC voltage signals
US5381007A (en) *	1991-02-28	1995-01-10	Teledyne Mec A Division Of Teledyne Industries, Inc.	Mass spectrometry method with two applied trapping fields having same spatial form
GB2267385B (en) *	1992-05-29	1995-12-13	Finnigan Corp	Method of detecting the ions in an ion trap mass spectrometer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0409362B1 (de) *	1985-05-24	1995-04-19	Finnigan Corporation	Betriebsverfahren für eine Ionenfalle
US4749860A (en) *	1986-06-05	1988-06-07	Finnigan Corporation	Method of isolating a single mass in a quadrupole ion trap

1992
- 1992-02-11 CA CA002101152A patent/CA2101152C/en not_active Expired - Lifetime
- 1992-02-11 JP JP4507289A patent/JP2743034B2/ja not_active Expired - Fee Related
- 1992-02-11 ES ES92907848T patent/ES2106177T3/es not_active Expired - Lifetime
- 1992-02-11 AT AT92907848T patent/ATE151915T1/de not_active IP Right Cessation
- 1992-02-11 EP EP92907848A patent/EP0573579B1/de not_active Expired - Lifetime
- 1992-02-11 DE DE69219113T patent/DE69219113T2/de not_active Expired - Lifetime
- 1992-02-11 DK DK92907848.3T patent/DK0573579T3/da active
- 1992-02-11 WO PCT/US1992/001104 patent/WO1992015392A1/en not_active Ceased

Also Published As

Publication number	Publication date
CA2101152A1 (en)	1992-08-29
EP0573579A1 (de)	1993-12-15
EP0573579B1 (de)	1997-04-16
DE69219113D1 (de)	1997-05-22
DK0573579T3 (da)	1997-10-20
ATE151915T1 (de)	1997-05-15
ES2106177T3 (es)	1997-11-01
JP2743034B2 (ja)	1998-04-22
EP0573579A4 (de)	1995-08-09
WO1992015392A1 (en)	1992-09-17
DE69219113T2 (de)	1997-11-20
JPH06508469A (ja)	1994-09-22

Legal Events

Date	Code	Title	Description
1993-09-15	EEER	Examination request
2012-02-11	MKEX	Expiry

Publication	Publication Date	Title
CA2116344C (en)	2002-07-02	Mass spectrometry method using supplemental ac voltage signals
EP0736221B1 (de)	2005-08-10	Massenspektrometrisches verfahren mit zwei sperrfeldern gleicher form
US5466931A (en)	1995-11-14	Mass spectrometry method using notch filter
US5610397A (en)	1997-03-11	Mass spectrometry method using supplemental AC voltage signals
US5075547A (en)	1991-12-24	Quadrupole ion trap mass spectrometer having two pulsed axial excitation input frequencies and method of parent and neutral loss scanning and selected reaction monitoring
US5171991A (en)	1992-12-15	Quadrupole ion trap mass spectrometer having two axial modulation excitation input frequencies and method of parent and neutral loss scanning
US5196699A (en)	1993-03-23	Chemical ionization mass spectrometry method using notch filter
US5206507A (en)	1993-04-27	Mass spectrometry method using filtered noise signal
US5451782A (en)	1995-09-19	Mass spectometry method with applied signal having off-resonance frequency
CA2101152C (en)	1999-03-30	Mass spectrometry method using supplemental ac voltage signals
US5173604A (en)	1992-12-22	Mass spectrometry method with non-consecutive mass order scan
EP0765190B1 (de)	1999-12-29	Quadrupol mit einem von der resonanzfrequenz abweichenden angelegten signal