CA2103665C - Agents antiretroviraux oligopeptidiques - Google Patents

Agents antiretroviraux oligopeptidiques Download PDF

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Publication number
CA2103665C
CA2103665C CA002103665A CA2103665A CA2103665C CA 2103665 C CA2103665 C CA 2103665C CA 002103665 A CA002103665 A CA 002103665A CA 2103665 A CA2103665 A CA 2103665A CA 2103665 C CA2103665 C CA 2103665C
Authority
CA
Canada
Prior art keywords
residue
dicarboxylic acid
compound
formula
use according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002103665A
Other languages
English (en)
Other versions
CA2103665A1 (fr
Inventor
J. William Lown
Ronald George Micetich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
Original Assignee
University of Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Alberta filed Critical University of Alberta
Publication of CA2103665A1 publication Critical patent/CA2103665A1/fr
Application granted granted Critical
Publication of CA2103665C publication Critical patent/CA2103665C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002103665A 1991-02-06 1992-02-05 Agents antiretroviraux oligopeptidiques Expired - Fee Related CA2103665C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65061691A 1991-02-06 1991-02-06
US650,616 1991-02-06
PCT/CA1992/000051 WO1992013838A1 (fr) 1991-02-06 1992-02-05 Agents antiretroviraux oligopeptidiques

Publications (2)

Publication Number Publication Date
CA2103665A1 CA2103665A1 (fr) 1992-08-07
CA2103665C true CA2103665C (fr) 2003-04-15

Family

ID=24609608

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002103665A Expired - Fee Related CA2103665C (fr) 1991-02-06 1992-02-05 Agents antiretroviraux oligopeptidiques

Country Status (4)

Country Link
AU (1) AU1224392A (fr)
CA (1) CA2103665C (fr)
WO (1) WO1992013838A1 (fr)
ZA (1) ZA92864B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives
GB9307948D0 (en) * 1993-04-16 1993-06-02 Erba Carlo Spa Biologically active ureido derivatives useful in the treatment of lentivirus-induced disease
AU7380294A (en) * 1993-08-06 1995-02-28 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
US6143901A (en) * 1996-07-31 2000-11-07 Genesoft, Inc. Complex formation between dsDNA and pyrrole imidazole polyamides
US6090947A (en) 1996-02-26 2000-07-18 California Institute Of Technology Method for the synthesis of pyrrole and imidazole carboxamides on a solid support
US6635417B1 (en) 1996-07-31 2003-10-21 California Institute Of Technology Complex formation between DSDNA and oligomer of cyclic heterocycles
AU6757698A (en) 1996-02-26 1998-10-30 California Institute Of Technology Stereochemical control of the dna binding affinity, sequence specificity, and orientation-preference of chiral hairpin polyamides in the minor groove
AU734715B2 (en) 1996-02-26 2001-06-21 California Institute Of Technology Improved polyamides for binding in the minor groove of double stranded DNA
US6555692B1 (en) 1996-02-26 2003-04-29 California Institute Of Technology Preparation and use of bifunctional molecules having DNA sequence binding specificity
US6506906B1 (en) 1996-02-26 2003-01-14 California Institute Of Technology Preparation and use of bifunctional molecules having DNA sequence binding specificity
US5998140A (en) 1996-07-31 1999-12-07 The Scripps Research Institute Complex formation between dsDNA and oligomer of cyclic heterocycles
JP2003529609A (ja) 2000-03-16 2003-10-07 ジーンソフト インコーポレイティッド 核酸結合部分を含む荷電した化合物およびその利用法
US7078536B2 (en) 2001-03-14 2006-07-18 Genesoft Pharmaceuticals, Inc. Charged compounds comprising a nucleic acid binding moiety and uses therefor
US7122626B2 (en) 2001-04-26 2006-10-17 Genesoft Pharmceuticals, Inc. Halogen-substitued thienyl compounds
ATE425753T1 (de) 2002-08-02 2009-04-15 Genesoft Pharmaceuticals Inc Biaryl-verbindungen mit antiinfektiver wirkung
US7265129B2 (en) 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
CA2508769A1 (fr) 2002-12-10 2004-06-24 Oscient Pharmaceuticals Corporation Composes antibacteriens possedant un motif (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide)
DE102004055582A1 (de) * 2004-11-18 2006-05-24 Bayer Cropscience Ag N-Heterocyclyl-phthalsäurediamide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4665184A (en) * 1983-10-12 1987-05-12 California Institute Of Technology Bifunctional molecules having a DNA intercalator or DNA groove binder linked to ethylene diamine tetraacetic acid
CN85103908A (zh) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 制备4′-表多克索红菌素的新方法
SE468642B (sv) * 1985-07-16 1993-02-22 Erba Farmitalia Poly-4-aminopyrrol-2-karboxamidoderivat och foerfarande foer deras framstaellning och en farmaceutisk komposition
CA1308516C (fr) * 1987-07-06 1992-10-06 The Governors Of The University Of Alberta Agents antiviraux et anticancereux oligopeptidiques
GB9000644D0 (en) * 1990-01-11 1990-03-14 Erba Carlo Spa New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds

Also Published As

Publication number Publication date
ZA92864B (en) 1993-01-27
AU1224392A (en) 1992-09-07
WO1992013838A1 (fr) 1992-08-20
CA2103665A1 (fr) 1992-08-07

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