CA2104217A1 - Traitement de l'endotoxemie - Google Patents

Traitement de l'endotoxemie

Info

Publication number: CA2104217A1
Authority: CA; Canada
Prior art keywords: fragment; receptor protein; protein; scavenger receptor; pharmaceutical composition
Prior art date: 1991-02-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA 2104217

Other languages

English (en)

Inventor

Monty Krieger

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Massachusetts Institute of Technology

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-02-22

Filing date

1992-02-21

Publication date

1992-08-23

1992-02-21 Application filed by Individual filed Critical Individual

1992-08-23 Publication of CA2104217A1 publication Critical patent/CA2104217A1/fr

Status Abandoned legal-status Critical Current

Links

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ZJYYHGLJYGJLLN-UHFFFAOYSA-N guanidinium thiocyanate Chemical compound SC#N.NC(N)=N ZJYYHGLJYGJLLN-UHFFFAOYSA-N 0.000 description 1
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CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
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239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
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125000003607 serino group Chemical group [H]N([H])[C@]([H])(C(=O)[*])C(O[H])([H])[H] 0.000 description 1
ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
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238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
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125000001424 substituent group Chemical group 0.000 description 1
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229960004267 taurolidine Drugs 0.000 description 1
AJKIRUJIDFJUKJ-UHFFFAOYSA-N taurolidine Chemical compound C1NS(=O)(=O)CCN1CN1CNS(=O)(=O)CC1 AJKIRUJIDFJUKJ-UHFFFAOYSA-N 0.000 description 1
229950007343 taurultam Drugs 0.000 description 1
238000012360 testing method Methods 0.000 description 1
RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
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LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Immunology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cell Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

CA 2104217 1991-02-22 1992-02-21 Traitement de l'endotoxemie Abandoned CA2104217A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US66222791A	1991-02-22	1991-02-22
US662,227		1991-02-22

Publications (1)

Publication Number	Publication Date
CA2104217A1 true CA2104217A1 (fr)	1992-08-23

Family

ID=24656904

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA 2104217 Abandoned CA2104217A1 (fr)	1991-02-22	1992-02-21	Traitement de l'endotoxemie

Country Status (4)

Country	Link
EP (1)	EP0572541A1 (fr)
JP (1)	JPH06508604A (fr)
CA (1)	CA2104217A1 (fr)
WO (1)	WO1992014482A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5624904A (en) *	1993-11-17	1997-04-29	Massachusetts Institute Of Technology	Method for treating gram positive septicemia
US5691197A (en) *	1995-02-21	1997-11-25	Tryggvason; Karl	Isolated DNA sequence for a novel macrophage receptor with a collagenous domain
US5683903A (en) *	1995-05-30	1997-11-04	Smithkline Beecham Corporation	Attachment enhanced 293 cells
WO2002064770A1 (fr) *	2001-02-15	2002-08-22	Mochida Pharmaceutical Co., Ltd.	Nouvelle proteine de classe a du type recepteur eboueur
JP2011093804A (ja) *	2008-02-13	2011-05-12	Kyoto Sangyo Univ	関節リウマチ治療剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU3772289A (en) *	1988-06-23	1990-01-12	Associates Of Cape Cod, Inc.	Endotoxin binding protein and uses thereof

1992
- 1992-02-21 CA CA 2104217 patent/CA2104217A1/fr not_active Abandoned
- 1992-02-21 JP JP4507346A patent/JPH06508604A/ja active Pending
- 1992-02-21 WO PCT/US1992/001370 patent/WO1992014482A1/fr not_active Ceased
- 1992-02-21 EP EP19920907392 patent/EP0572541A1/fr not_active Withdrawn

Also Published As

Publication number	Publication date
WO1992014482A1 (fr)	1992-09-03
EP0572541A1 (fr)	1993-12-08
JPH06508604A (ja)	1994-09-29

Legal Events

Date	Code	Title	Description
1995-08-21	FZDE	Dead

Publication	Publication Date	Title
Kodama et al.	1990	Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils
DE60219611T2 (de)	2007-12-27	Modifizierte annexin-proteine und verhinderung und behandlung von thrombose
US6323313B1 (en)	2001-11-27	Annexin derivative with endogenous chelation sites
US5510466A (en)	1996-04-23	Scavenger receptor protein and antibody thereto
RU2177480C2 (ru)	2001-12-27	Полипептид, способ получения (варианты), днк (варианты), вектор (варианты), клетка, применение полипептида, фармацевтическая композиция (варианты)
US5700909A (en)	1997-12-23	Prosaposin and cytokine-derived peptides
KR100537558B1 (ko)	2005-12-19	인터류킨-18 결합 단백질
EP0162414A2 (fr)	1985-11-27	Peptides amphipathiques et les compositions pharmaceutiques les contenant
IL83878A (en)	1995-07-31	Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
CA2104217A1 (fr)	1992-08-23	Traitement de l'endotoxemie
EP0550506B1 (fr)	2002-11-20	Nouveau facteur chimiotactique
US6083688A (en)	2000-07-04	Platelet glycoprotein V gene and uses
US5650389A (en)	1997-07-22	Methods for the inhibition of complement activation
JP2001507227A (ja)	2001-06-05	小脳および胚に特異的なタンパク質
EP0529622A2 (fr)	1993-03-03	Clonage et caractérisation de l'adénylyl-cyclase cardiaque
JPH1169985A (ja)	1999-03-16	慢性腎不全の標的およびマーカーであるＣＲＦＧ−１ａ
WO1993018161A1 (fr)	1993-09-16	Complexes recepteurs a b29 (ig-beta ou ig-gamma) et leurs utilisations
US6551796B1 (en)	2003-04-22	Nucleic acid encoding urate transporter and methods of use thereof
JPH107698A (ja)	1998-01-13	エピモルフィン・アンタゴニスト
JPH11505104A (ja)	1999-05-18	リンパ球インターフェロン調節因子（ｌｓｉｒｆ）ポリペプチドをコードする遺伝子
US6069128A (en)	2000-05-30	Transiently membrane-permeable derivatives converted intracellularly into active peptides
JPH06100589A (ja)	1994-04-12	新規な蛋白性生理活性物質およびそのｄｎａ
EP0867449A1 (fr)	1998-09-30	Proteine d'adhesion de cellules, agent immunosuppresseur contenant cette proteine et agent immunosuppresseur renfermant des cellules ainsi induites
AU652575B2 (en)	1994-09-01	Novel chemotactic factor
HK1017820B (en)	2005-11-18	Tnf-receptor, tnf-binding protein and dna coding therefor