CA2106764A1 - Polypeptides substitues en ó presentant une activite therapeutique - Google Patents
Polypeptides substitues en ó presentant une activite therapeutiqueInfo
- Publication number
- CA2106764A1 CA2106764A1 CA002106764A CA2106764A CA2106764A1 CA 2106764 A1 CA2106764 A1 CA 2106764A1 CA 002106764 A CA002106764 A CA 002106764A CA 2106764 A CA2106764 A CA 2106764A CA 2106764 A1 CA2106764 A1 CA 2106764A1
- Authority
- CA
- Canada
- Prior art keywords
- methyl
- alpha
- carbonyl
- tryptophyl
- phenylalaninamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06156—Dipeptides with the first amino acid being heterocyclic and Trp-amino acid; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69075591A | 1991-04-24 | 1991-04-24 | |
| US690,755 | 1991-04-24 | ||
| US85208692A | 1992-03-20 | 1992-03-20 | |
| US852,086 | 1992-03-20 | ||
| PCT/US1992/003119 WO1992019254A1 (fr) | 1991-04-24 | 1992-04-15 | POLYPEPTIDES α SUBSTITUES AYANT DES PROPRIETES THERAPEUTIQUES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2106764A1 true CA2106764A1 (fr) | 1992-10-25 |
Family
ID=27104664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002106764A Abandoned CA2106764A1 (fr) | 1991-04-24 | 1992-04-15 | Polypeptides substitues en ó presentant une activite therapeutique |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0668770A1 (fr) |
| JP (1) | JPH06507402A (fr) |
| AU (1) | AU1907292A (fr) |
| CA (1) | CA2106764A1 (fr) |
| IE (1) | IE921321A1 (fr) |
| NZ (1) | NZ242441A (fr) |
| PT (1) | PT100422A (fr) |
| WO (1) | WO1992019254A1 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU674525B2 (en) * | 1992-06-01 | 1997-01-02 | Magainin Pharmaceuticals, Inc. | Biologically active peptides having N-terminal substitutions |
| WO1994009031A1 (fr) * | 1992-10-19 | 1994-04-28 | Warner-Lambert Company | Analogues de cholecystokinine (30-33) contenant un acide amine a substitution alpha |
| FR2700472B1 (fr) | 1993-01-19 | 1995-02-17 | Rhone Poulenc Rorer Sa | Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2. |
| WO1995012611A1 (fr) * | 1993-11-01 | 1995-05-11 | Japat Ltd. | Antagonistes de recepteur d'endotheline |
| US5610145A (en) * | 1994-04-15 | 1997-03-11 | Warner-Lambert Company | Tachykinin antagonists |
| US5554644A (en) * | 1994-06-08 | 1996-09-10 | Warner-Lambert Company | Tachykinin (NK2) antagonists |
| FR2735687B1 (fr) * | 1995-06-21 | 1997-08-14 | Sederma Sa | Nouvelles compositions cosmetiques amincissantes |
| US6372717B1 (en) * | 1996-08-23 | 2002-04-16 | Sederma S.A. | Synthetic peptides and their use in cosmetic or dermopharmaceutical compositions |
| IL137820A (en) | 2000-08-10 | 2009-06-15 | S I S Shulov Inst For Science | Pharmaceutical composition for topical administration comprising an analgesic peptide |
| US6593362B2 (en) | 2001-05-21 | 2003-07-15 | Guilford Pharmaceuticals Inc. | Non-peptidic cyclophilin binding compounds and their use |
| WO2006049681A2 (fr) * | 2004-08-30 | 2006-05-11 | Bayer Pharmaceuticals Corporation | Agonistes recepteur y2 neuropeptidiques selectifs |
| WO2009040020A1 (fr) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Amyline utilisée comme agent thérapeutique |
| HUP0700782A3 (en) * | 2007-12-05 | 2009-11-30 | Biostatin Gyogyszerkutato Fejl | Novel peptides and amino acid derivatives, pharmaceutical compositions containing the same and use of the compounds |
| HUE030152T2 (en) | 2011-03-28 | 2017-04-28 | S I S Shulov Innovative Science Ltd | A method for treating skin diseases |
| WO2025049670A1 (fr) * | 2023-08-31 | 2025-03-06 | Northwestern University | Composés et méthodes pour traiter des troubles du système nerveux central |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK309379A (da) * | 1978-07-24 | 1980-01-25 | Merck & Co Inc | Fremgangsmaade til fremstilling af aminosyrer og aminosyreestere |
| US4505853A (en) * | 1983-11-18 | 1985-03-19 | Ortho Pharmaceutical Corporation | Enzyme-resistant immunomodulatory peptides |
| US4689318A (en) * | 1985-08-29 | 1987-08-25 | The Salk Institute For Biological Studies | GRF analogs |
| US5098995A (en) * | 1987-05-22 | 1992-03-24 | The Salk Institute For Biological Studies | GRF Analogs VIIA |
| NZ229004A (en) * | 1988-05-19 | 1993-09-27 | Immunobiology Res Inst Inc | Tetrapeptides having t cell helper acitivity |
| NZ234264A (en) * | 1989-06-29 | 1993-05-26 | Warner Lambert Co | N-substituted cycloalkyl and polycycloalkyl alpha-substituted trp-phe- and phenethylamine derivatives, and pharmaceutical compositions |
-
1992
- 1992-04-15 AU AU19072/92A patent/AU1907292A/en not_active Abandoned
- 1992-04-15 JP JP4511401A patent/JPH06507402A/ja active Pending
- 1992-04-15 CA CA002106764A patent/CA2106764A1/fr not_active Abandoned
- 1992-04-15 WO PCT/US1992/003119 patent/WO1992019254A1/fr not_active Ceased
- 1992-04-15 EP EP92911434A patent/EP0668770A1/fr not_active Withdrawn
- 1992-04-22 NZ NZ242441A patent/NZ242441A/en unknown
- 1992-04-23 PT PT100422A patent/PT100422A/pt not_active Application Discontinuation
- 1992-04-23 IE IE132192A patent/IE921321A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1907292A (en) | 1992-12-21 |
| EP0668770A1 (fr) | 1995-08-30 |
| IE921321A1 (en) | 1992-11-04 |
| NZ242441A (en) | 1995-02-24 |
| JPH06507402A (ja) | 1994-08-25 |
| WO1992019254A1 (fr) | 1992-11-12 |
| PT100422A (pt) | 1993-09-30 |
| EP0668770A4 (fr) | 1995-09-27 |
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