CA2107100A1 - Fragments therapeutiques du facteur de von willebrand - Google Patents

Fragments therapeutiques du facteur de von willebrand

Info

Publication number
CA2107100A1
CA2107100A1 CA 2107100 CA2107100A CA2107100A1 CA 2107100 A1 CA2107100 A1 CA 2107100A1 CA 2107100 CA2107100 CA 2107100 CA 2107100 A CA2107100 A CA 2107100A CA 2107100 A1 CA2107100 A1 CA 2107100A1
Authority
CA
Canada
Prior art keywords
vwf
polypeptide
fragment
subunit
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2107100
Other languages
English (en)
Inventor
Zaverio M. Ruggeri
Jerry L. Ware
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of CA2107100A1 publication Critical patent/CA2107100A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 2107100 1991-03-27 1992-03-27 Fragments therapeutiques du facteur de von willebrand Abandoned CA2107100A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67552991A 1991-03-27 1991-03-27
US675,529 1991-03-27

Publications (1)

Publication Number Publication Date
CA2107100A1 true CA2107100A1 (fr) 1992-09-28

Family

ID=24710889

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2107100 Abandoned CA2107100A1 (fr) 1991-03-27 1992-03-27 Fragments therapeutiques du facteur de von willebrand

Country Status (4)

Country Link
EP (1) EP0648268A1 (fr)
AU (1) AU1757592A (fr)
CA (1) CA2107100A1 (fr)
WO (1) WO1992017192A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110624105A (zh) * 2019-09-24 2019-12-31 苏州大学 血管性血友病因子的结构敏感多肽抗原的序列

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5847086A (en) * 1991-06-20 1998-12-08 Centeon L.L.C. Therapeutic fragments of von Willebrand factor
FR2686901A1 (fr) * 1992-01-31 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux polypeptides antithrombotiques, leur preparation et compositions pharmaceutiques les contenant.
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FI20010492A0 (fi) * 2001-03-12 2001-03-12 Licentia Oy Uuden von Willebrandin tekijän A3-domeenissa sijaitsevan funktionaalisen sitomiskohdan identifiointi verihiutaleintegriini alfaIIbbeta3 :a varten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
MX9203763A (es) * 1991-06-28 1993-08-01 Rhone Poulenc Rorer Int Polipeptidos terapeuticos a base del factor de von willebrand

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110624105A (zh) * 2019-09-24 2019-12-31 苏州大学 血管性血友病因子的结构敏感多肽抗原的序列

Also Published As

Publication number Publication date
EP0648268A4 (fr) 1994-04-20
WO1992017192A1 (fr) 1992-10-15
AU1757592A (en) 1992-11-02
EP0648268A1 (fr) 1995-04-19

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Legal Events

Date Code Title Description
FZDE Dead