EP0648268A4 - Fragments therapeutiques du facteur willebrand. - Google Patents

Fragments therapeutiques du facteur willebrand.

Info

Publication number
EP0648268A4
EP0648268A4 EP19920909515 EP92909515A EP0648268A4 EP 0648268 A4 EP0648268 A4 EP 0648268A4 EP 19920909515 EP19920909515 EP 19920909515 EP 92909515 A EP92909515 A EP 92909515A EP 0648268 A4 EP0648268 A4 EP 0648268A4
Authority
EP
European Patent Office
Prior art keywords
von willebrand
willebrand factor
therapeutic fragments
fragments
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP19920909515
Other languages
German (de)
English (en)
Other versions
EP0648268A1 (fr
Inventor
Zaverio M Ruggeri
Jerry L Ware
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of EP0648268A4 publication Critical patent/EP0648268A4/fr
Publication of EP0648268A1 publication Critical patent/EP0648268A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
EP92909515A 1991-03-27 1992-03-27 Fragments therapeutiques du facteur willebrand Withdrawn EP0648268A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67552991A 1991-03-27 1991-03-27
PCT/US1992/002475 WO1992017192A1 (fr) 1991-03-27 1992-03-27 Fragments therapeutiques du facteur willebrand
US675529 1996-07-03

Publications (2)

Publication Number Publication Date
EP0648268A4 true EP0648268A4 (fr) 1994-04-20
EP0648268A1 EP0648268A1 (fr) 1995-04-19

Family

ID=24710889

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92909515A Withdrawn EP0648268A1 (fr) 1991-03-27 1992-03-27 Fragments therapeutiques du facteur willebrand

Country Status (4)

Country Link
EP (1) EP0648268A1 (fr)
AU (1) AU1757592A (fr)
CA (1) CA2107100A1 (fr)
WO (1) WO1992017192A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5847086A (en) * 1991-06-20 1998-12-08 Centeon L.L.C. Therapeutic fragments of von Willebrand factor
FR2686901A1 (fr) * 1992-01-31 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux polypeptides antithrombotiques, leur preparation et compositions pharmaceutiques les contenant.
US6197526B1 (en) * 1999-01-04 2001-03-06 Dyax Corp. Polypeptides for binding human factor VIII and fragments of human factor VIII
US7112438B2 (en) 1999-01-04 2006-09-26 Dyax Corp. Binding molecules for human factor VIII and factor VIII-like proteins
FI20010492A0 (fi) * 2001-03-12 2001-03-12 Licentia Oy Uuden von Willebrandin tekijän A3-domeenissa sijaitsevan funktionaalisen sitomiskohdan identifiointi verihiutaleintegriini alfaIIbbeta3 :a varten
CN110624105B (zh) * 2019-09-24 2021-06-11 苏州大学 血管性血友病因子的结构敏感多肽抗原的序列

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000357A1 (fr) * 1991-06-28 1993-01-07 Rhone-Poulenc Rorer International (Holdings) Inc. Polypeptides therapeutiques bases sur le facteur de von villebrand

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000357A1 (fr) * 1991-06-28 1993-01-07 Rhone-Poulenc Rorer International (Holdings) Inc. Polypeptides therapeutiques bases sur le facteur de von villebrand

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FILE SERVER STN KARLSRUHE,FILE MEDLINE ABSTRACT NO.91185601 & J CLIN INVEST, (1991 APR) 87(4) 1220-6 *
FILE SERVER STN KARLSRUHE,FILE MEDLINE ABSTRACT NO.91187908 & PROC NATL ACAD SCI USA, (1991 APR 1) 88(7) 2946-50 *
See also references of WO9217192A1 *

Also Published As

Publication number Publication date
WO1992017192A1 (fr) 1992-10-15
AU1757592A (en) 1992-11-02
CA2107100A1 (fr) 1992-09-28
EP0648268A1 (fr) 1995-04-19

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Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 19931027

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE DK ES FR GB GR IT LI LU MC NL SE

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 19941001

RHK1 Main classification (correction)

Ipc: C12N 15/12