CA2182080C - Techniques de spectrophotometrie - Google Patents

Techniques de spectrophotometrie Download PDF

Info

Publication number: CA2182080C
Authority: CA; Canada
Prior art keywords: cavity; sample; plate; additional structure; reflective
Prior art date: 1994-03-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA002182080A

Other languages

English (en)

Other versions

CA2182080A1 (fr

Inventor

Grenville Arthur Robinson

Alan Derek Cookson

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Serono SA

Original Assignee

Applied Research Systems ARS Holding NV

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-10

Filing date

1995-03-09

Publication date

2007-01-23

1994-03-10 Priority claimed from GB9404749A external-priority patent/GB9404749D0/en

1995-03-09 Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV

1995-09-14 Publication of CA2182080A1 publication Critical patent/CA2182080A1/fr

2007-01-23 Application granted granted Critical

2007-01-23 Publication of CA2182080C publication Critical patent/CA2182080C/fr

2015-03-09 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

238000000034 method Methods 0.000 title claims description 17
238000000576 coating method Methods 0.000 claims abstract description 26
239000011248 coating agent Substances 0.000 claims abstract description 23
239000007788 liquid Substances 0.000 claims abstract description 23
238000003556 assay Methods 0.000 claims abstract description 9
239000007787 solid Substances 0.000 claims abstract description 8
230000005855 radiation Effects 0.000 claims description 21
238000012544 monitoring process Methods 0.000 claims description 4
230000001678 irradiating effect Effects 0.000 claims description 3
238000005259 measurement Methods 0.000 claims 1
239000000523 sample Substances 0.000 description 31
239000000463 material Substances 0.000 description 16
229910052751 metal Inorganic materials 0.000 description 4
239000002184 metal Substances 0.000 description 4
238000002798 spectrophotometry method Methods 0.000 description 4
238000001514 detection method Methods 0.000 description 3
239000011521 glass Substances 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
239000000126 substance Substances 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
239000004411 aluminium Substances 0.000 description 2
229910052782 aluminium Inorganic materials 0.000 description 2
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
239000003153 chemical reaction reagent Substances 0.000 description 2
238000007796 conventional method Methods 0.000 description 2
230000005670 electromagnetic radiation Effects 0.000 description 2
BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
238000000159 protein binding assay Methods 0.000 description 2
230000009870 specific binding Effects 0.000 description 2
238000010998 test method Methods 0.000 description 2
229920002972 Acrylic fiber Polymers 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
239000000853 adhesive Substances 0.000 description 1
230000001070 adhesive effect Effects 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
230000004888 barrier function Effects 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
239000012472 biological sample Substances 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 description 1
229910001634 calcium fluoride Inorganic materials 0.000 description 1
238000005515 capillary zone electrophoresis Methods 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
229920006332 epoxy adhesive Polymers 0.000 description 1
239000003822 epoxy resin Substances 0.000 description 1
230000008020 evaporation Effects 0.000 description 1
238000001704 evaporation Methods 0.000 description 1
239000012530 fluid Substances 0.000 description 1
239000008103 glucose Substances 0.000 description 1
PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
229910052737 gold Inorganic materials 0.000 description 1
239000010931 gold Substances 0.000 description 1
238000005286 illumination Methods 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
239000002245 particle Substances 0.000 description 1
229910052698 phosphorus Inorganic materials 0.000 description 1
239000011574 phosphorus Substances 0.000 description 1
239000004033 plastic Substances 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
229920000647 polyepoxide Polymers 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
239000010453 quartz Substances 0.000 description 1
239000012088 reference solution Substances 0.000 description 1
239000012488 sample solution Substances 0.000 description 1
238000005070 sampling Methods 0.000 description 1
238000007650 screen-printing Methods 0.000 description 1
238000007789 sealing Methods 0.000 description 1
VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
239000004332 silver Substances 0.000 description 1
229910052709 silver Inorganic materials 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000002904 solvent Substances 0.000 description 1
239000010409 thin film Substances 0.000 description 1
238000012546 transfer Methods 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0822—Slides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/168—Specific optical properties, e.g. reflective coatings
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Dispersion Chemistry (AREA)
Hematology (AREA)
Clinical Laboratory Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Optical Measuring Cells (AREA)

CA002182080A 1994-03-10 1995-03-09 Techniques de spectrophotometrie Expired - Fee Related CA2182080C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB9404749A GB9404749D0 (en)	1994-03-10	1994-03-10	Device for use in spectrophotometry
GB9404749.5		1994-03-10
PCT/GB1995/000507 WO1995024632A1 (fr)	1994-03-10	1995-03-09	Techniques spectrophotometriques

Publications (2)

Publication Number	Publication Date
CA2182080A1 CA2182080A1 (fr)	1995-09-14
CA2182080C true CA2182080C (fr)	2007-01-23

Family

ID=37684132

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002182080A Expired - Fee Related CA2182080C (fr)	1994-03-10	1995-03-09	Techniques de spectrophotometrie

Country Status (1)

Country	Link
CA (1)	CA2182080C (fr)

1995
- 1995-03-09 CA CA002182080A patent/CA2182080C/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2182080A1 (fr)	1995-09-14

Legal Events

Date	Code	Title	Description
2001-11-19	EEER	Examination request
2010-03-09	MKLA	Lapsed

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