CA2199809A1 - Derives synthetiques de gangliosides - Google Patents

Derives synthetiques de gangliosides

Info

Publication number
CA2199809A1
CA2199809A1 CA002199809A CA2199809A CA2199809A1 CA 2199809 A1 CA2199809 A1 CA 2199809A1 CA 002199809 A CA002199809 A CA 002199809A CA 2199809 A CA2199809 A CA 2199809A CA 2199809 A1 CA2199809 A1 CA 2199809A1
Authority
CA
Canada
Prior art keywords
suppressing
immune response
ganglioside
animal
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002199809A
Other languages
English (en)
Other versions
CA2199809C (fr
Inventor
Akira Hasegawa
Stephan Ladisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2199809A1 publication Critical patent/CA2199809A1/fr
Application granted granted Critical
Publication of CA2199809C publication Critical patent/CA2199809C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
CA002199809A 1994-09-14 1995-09-14 Derives synthetiques de gangliosides Expired - Lifetime CA2199809C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/305,832 US5567684A (en) 1994-09-14 1994-09-14 Synthetic ganglioside derivatives
US08/305,832 1994-09-14
PCT/US1995/011670 WO1996008257A1 (fr) 1994-09-14 1995-09-14 Derives synthetiques de gangliosides

Publications (2)

Publication Number Publication Date
CA2199809A1 true CA2199809A1 (fr) 1996-03-21
CA2199809C CA2199809C (fr) 2008-07-29

Family

ID=23182557

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002199809A Expired - Lifetime CA2199809C (fr) 1994-09-14 1995-09-14 Derives synthetiques de gangliosides

Country Status (8)

Country Link
US (1) US5567684A (fr)
EP (1) EP0783311B1 (fr)
JP (2) JP4727767B2 (fr)
AT (1) ATE247475T1 (fr)
AU (1) AU3632395A (fr)
CA (1) CA2199809C (fr)
DE (1) DE69531546T2 (fr)
WO (1) WO1996008257A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
AU683026B2 (en) * 1992-10-22 1997-10-30 Kirin Pharma Kabushiki Kaisha Novel shingoglycolipid and use thereof
EP0694558B1 (fr) * 1993-04-15 1999-01-27 Kirin Beer Kabushiki Kaisha Nouveau sphingoglycolipide et son utilisation
JPH08176185A (ja) * 1994-12-19 1996-07-09 Toa Boshoku Kk 糖脂質合成中間体
EP1438387A4 (fr) * 2001-09-14 2004-10-13 Momenta Pharmaceuticals Inc Procedes de fabrication de glycomolecules a activite amelioree, et utilisations de ces dernieres
DE10226367A1 (de) * 2002-06-13 2003-12-24 Nutricia Nv Ganglioside mit modifizierter Acylfunktion
JP2010524467A (ja) 2007-04-16 2010-07-22 モメンタ ファーマシューティカルズ インコーポレイテッド 規定の糖タンパク質産物および関連の方法
WO2011127322A1 (fr) 2010-04-07 2011-10-13 Momenta Pharmaceuticals, Inc. Glycanes à haute teneur en mannose
EP2686671A4 (fr) 2011-03-12 2015-06-24 Momenta Pharmaceuticals Inc N-glycanes contenant de la n-acétylhexosamine dans des produits de glycoprotéines
WO2013181575A2 (fr) 2012-06-01 2013-12-05 Momenta Pharmaceuticals, Inc. Méthodes associées au denosumab
EP2877589B1 (fr) 2012-07-26 2024-03-06 Momenta Pharmaceuticals, Inc. Glycoprotéines ayant des propriétés anti-inflammatoires
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
WO2014186310A1 (fr) 2013-05-13 2014-11-20 Momenta Pharmaceuticals, Inc. Méthodes de traitement de la neurodégénérescence
WO2015057622A1 (fr) 2013-10-16 2015-04-23 Momenta Pharmaceuticals, Inc. Glycoprotéines sialylées

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4388309A (en) * 1981-06-10 1983-06-14 Shanksville Corporation, N.V. Process for suppressing graft rejection in organ transplantation
JPS59164798A (ja) * 1983-03-09 1984-09-17 Rikagaku Kenkyusho シアル酸含有糖脂質誘導体
IT1212896B (it) * 1983-11-08 1989-11-30 Della Valle Francesco Metodo di somministrazione per via inalatoria di gangliosidi e derivati, e composizioni farmaceutiche relative
IT1199116B (it) * 1984-07-03 1988-12-30 Fidia Farmaceutici Derivati di gangliosidi
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
JP2782069B2 (ja) * 1988-08-12 1998-07-30 和光純薬工業株式会社 ガングリオシド類の新規な製造法
JPH02307974A (ja) * 1989-05-19 1990-12-21 Nippon Fine Chem Co Ltd セルロース系素材及びその加工品の改質剤
JPH03255028A (ja) * 1990-03-01 1991-11-13 Imeeji Meekaa:Kk 免疫抑制剤
JPH0476082A (ja) * 1990-07-18 1992-03-10 Shiseido Co Ltd ゲル化剤
US5371202A (en) * 1991-02-28 1994-12-06 The Nisshin Oil Mills, Ltd. Processes of preparing sialoglycosyl compounds
JPH04300891A (ja) * 1991-03-29 1992-10-23 Nisshin Oil Mills Ltd:The Ｓ−グリコシドを有するガングリオシド類縁体
WO1992017189A1 (fr) * 1991-03-29 1992-10-15 The Regents Of The University Of California Gangliosides presentant une activite d'immunodepression
JPH04353570A (ja) * 1991-05-31 1992-12-08 Asai Bussan Kk 防曇性樹脂組成物、防曇性成形体および防曇方法
WO1993002686A1 (fr) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides comprenant des fractions de ceramides a effet immunosuppresseur
US5399567A (en) * 1993-05-13 1995-03-21 Monsanto Company Method of treating cholera
JPH07228514A (ja) * 1993-12-21 1995-08-29 Nippon Fine Chem Co Ltd 酸化染毛剤組成物

Also Published As

Publication number Publication date
US5567684A (en) 1996-10-22
AU3632395A (en) 1996-03-29
JP4727767B2 (ja) 2011-07-20
EP0783311A4 (fr) 1998-12-23
DE69531546D1 (de) 2003-09-25
ATE247475T1 (de) 2003-09-15
JP2007262085A (ja) 2007-10-11
EP0783311B1 (fr) 2003-08-20
WO1996008257A1 (fr) 1996-03-21
CA2199809C (fr) 2008-07-29
EP0783311A1 (fr) 1997-07-16
JP5165283B2 (ja) 2013-03-21
JPH10508829A (ja) 1998-09-02
DE69531546T2 (de) 2004-06-17

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20150914