CA2206423C - Agent antithrombotique et anticorps monoclonaux contre le facteur de von willebrand - Google Patents

Agent antithrombotique et anticorps monoclonaux contre le facteur de von willebrand Download PDF

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Publication number
CA2206423C
CA2206423C CA002206423A CA2206423A CA2206423C CA 2206423 C CA2206423 C CA 2206423C CA 002206423 A CA002206423 A CA 002206423A CA 2206423 A CA2206423 A CA 2206423A CA 2206423 C CA2206423 C CA 2206423C
Authority
CA
Canada
Prior art keywords
monoclonal antibody
antibody
ferm
hybridoma
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002206423A
Other languages
English (en)
Other versions
CA2206423A1 (fr
Inventor
Mitsuyo Nagano
Hiroshi Yamamoto
Morikazu Kito
Ryota Yoshimoto
Tsuyoshi Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority claimed from PCT/JP1995/002435 external-priority patent/WO1996017078A1/fr
Publication of CA2206423A1 publication Critical patent/CA2206423A1/fr
Application granted granted Critical
Publication of CA2206423C publication Critical patent/CA2206423C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Cette invention se rapporte à un agent antithrombotique contenant comme ingrédient actif un anticorps monoclonal qui réagit avec le facteur de von Willebrand humain qui inhibe l'agrégation plaquettaire induite par ristocétine (APIR), l'agrégation plaquettaire induite par bottrocétine (APIB) et l'agrégation plaquettaire induite par le stress (APIS), et qui ne cause pas de saignement, même lorsqu'il est administré en quantité propre à produire l'effet antithrombotique.
CA002206423A 1994-11-30 1995-11-29 Agent antithrombotique et anticorps monoclonaux contre le facteur de von willebrand Expired - Fee Related CA2206423C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6-297070 1994-11-30
JP29707094 1994-11-30
PCT/JP1995/002435 WO1996017078A1 (fr) 1994-11-30 1995-11-29 Agent antithrombotique et anticorps monoclonaux contre le facteur de von willebrand

Publications (2)

Publication Number Publication Date
CA2206423A1 CA2206423A1 (fr) 1996-06-06
CA2206423C true CA2206423C (fr) 2006-07-25

Family

ID=36707764

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002206423A Expired - Fee Related CA2206423C (fr) 1994-11-30 1995-11-29 Agent antithrombotique et anticorps monoclonaux contre le facteur de von willebrand

Country Status (1)

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CA (1) CA2206423C (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021258160A1 (fr) * 2020-06-26 2021-12-30 Monash University Anticorps anti-vwf et leurs utilisations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021258160A1 (fr) * 2020-06-26 2021-12-30 Monash University Anticorps anti-vwf et leurs utilisations

Also Published As

Publication number Publication date
CA2206423A1 (fr) 1996-06-06

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Effective date: 20141201