CA2215042C - Assay reagents and devices - Google Patents

Assay reagents and devices Download PDF

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Publication number
CA2215042C
CA2215042C CA002215042A CA2215042A CA2215042C CA 2215042 C CA2215042 C CA 2215042C CA 002215042 A CA002215042 A CA 002215042A CA 2215042 A CA2215042 A CA 2215042A CA 2215042 C CA2215042 C CA 2215042C
Authority
CA
Canada
Prior art keywords
binding agent
analyte
specific binding
sensitised
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002215042A
Other languages
English (en)
French (fr)
Other versions
CA2215042A1 (en
Inventor
Yvonne Elizabeth Penfold
David Alan Percival
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alere Switzerland GmbH
Original Assignee
Inverness Medical Switzerland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inverness Medical Switzerland GmbH filed Critical Inverness Medical Switzerland GmbH
Publication of CA2215042A1 publication Critical patent/CA2215042A1/en
Application granted granted Critical
Publication of CA2215042C publication Critical patent/CA2215042C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/81—Tube, bottle, or dipstick

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002215042A 1996-09-27 1997-09-10 Assay reagents and devices Expired - Lifetime CA2215042C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96307078.4 1996-09-27
EP96307078A EP0833157B1 (de) 1996-09-27 1996-09-27 Testreagentien und Testvorrichtungen

Publications (2)

Publication Number Publication Date
CA2215042A1 CA2215042A1 (en) 1998-03-27
CA2215042C true CA2215042C (en) 2008-11-18

Family

ID=8225101

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002215042A Expired - Lifetime CA2215042C (en) 1996-09-27 1997-09-10 Assay reagents and devices

Country Status (8)

Country Link
US (3) US6133048A (de)
EP (1) EP0833157B1 (de)
JP (1) JP3939403B2 (de)
AT (1) ATE228247T1 (de)
AU (1) AU734197B2 (de)
CA (1) CA2215042C (de)
DE (1) DE69624920T2 (de)
ES (1) ES2187622T3 (de)

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US7713703B1 (en) 2000-11-13 2010-05-11 Biosite, Inc. Methods for monitoring the status of assays and immunoassays
US7198954B1 (en) * 1999-02-03 2007-04-03 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by hCG assay
US6500627B1 (en) * 1998-02-03 2002-12-31 The Trustees Of Columbia University In The City Of New York Methods for predicting pregnancy outcome in a subject by HCG assay
US6927034B2 (en) * 1998-02-03 2005-08-09 The Trustees Of Columbia University In The City Of New York Methods for detecting trophoblast malignancy by HCG assay
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
BE1012241A3 (fr) * 1998-10-21 2000-08-01 D Tek Procede de depistage d'analyte et trousse pour la mise en oeuvre d'un tel procede.
WO2000031538A1 (en) * 1998-11-23 2000-06-02 Praxsys Biosystems, Inc. Improved lateral flow assays
WO2001013116A1 (en) * 1999-08-11 2001-02-22 Unilever Plc Internally referenced immunoassay and test device
DE10009503A1 (de) 2000-02-29 2001-08-30 Roche Diagnostics Gmbh Verfahren zur Immobilisierung von Konjugaten in diagnostischen Tests
US20030162236A1 (en) * 2001-03-26 2003-08-28 Response Biomedical Corporation Compensation for variability in specific binding in quantitative assays
AU2002365682A1 (en) * 2001-12-04 2003-06-17 Lattec I/S Device for analysing analyte compounds and use hereof
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US7175992B2 (en) * 2002-04-10 2007-02-13 Response Biomedical Corporation Sensitive immunochromatographic assay
EP1493029B1 (de) * 2002-04-10 2010-03-31 Response Biomedical Corporation Sensitives immunochromatografisches assay
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
DE602004024236D1 (en) 2003-12-12 2009-12-31 Inverness Medical Switzerland Assay
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20050191704A1 (en) * 2004-03-01 2005-09-01 Kimberly-Clark Worldwide, Inc. Assay devices utilizing chemichromic dyes
EP1733232A1 (de) 2004-03-23 2006-12-20 Quidel Corporation Hybridphasen-lateralfluss-test
CN100357738C (zh) * 2004-03-26 2007-12-26 博奥生物有限公司 一种检测小分子化合物的方法
AU2005231107B8 (en) * 2004-03-30 2011-04-14 Global Life Sciences Solutions Usa Llc Lateral flow format, materials and methods
EP1794282A4 (de) * 2004-09-20 2011-03-23 Boston Microfluidics Mikrofluidische vorrichtung zur erkennung löslicher moleküle
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
US7803319B2 (en) 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US7439079B2 (en) 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US7858384B2 (en) 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
WO2007053186A2 (en) 2005-05-31 2007-05-10 Labnow, Inc. Methods and compositions related to determination and use of white blood cell counts
EP1929301A2 (de) * 2005-08-23 2008-06-11 Response Biomedical Corporation Mehrfach ausgerichtete immunchromatographische testverfahren
US7504235B2 (en) * 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
US8003399B2 (en) * 2005-08-31 2011-08-23 Kimberly-Clark Worldwide, Inc. Nitrite detection technique
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
US7279136B2 (en) 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7618810B2 (en) 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
US7871568B2 (en) 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
US8012761B2 (en) * 2006-12-14 2011-09-06 Kimberly-Clark Worldwide, Inc. Detection of formaldehyde in urine samples
US7846383B2 (en) * 2006-12-15 2010-12-07 Kimberly-Clark Worldwide, Inc. Lateral flow assay device and absorbent article containing same
US8377379B2 (en) * 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
US7935538B2 (en) 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
US7875433B2 (en) * 2007-02-26 2011-01-25 Response Biomedical Corporation Comparative multiple analyte assay
WO2009034563A2 (en) 2007-09-14 2009-03-19 Nanocomms Patents Limited An analysis system
JP5847158B2 (ja) 2010-04-07 2016-01-20 バイオセンシア パテンツ リミテッド アッセイのための流動制御デバイス
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
EP3044592B1 (de) 2013-09-13 2019-07-17 Symbolics, LLC Lateral-flow-tests mit zweidimensionalen test- und steuersignalauslesemustern
US11237163B2 (en) * 2016-03-07 2022-02-01 Quidel Cardiovascular Inc. Immunoassay controls and the use thereof

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Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
JPS5811575B2 (ja) * 1976-08-16 1983-03-03 帝国臓器製薬株式会社 抗原−抗体反応の測定法
JPS54108693A (en) * 1978-02-14 1979-08-25 Mitsubishi Chem Ind Method and device for optically measuring antigennantibody reaction
JPS60256057A (ja) * 1984-06-01 1985-12-17 Dai Ichi Pure Chem Co Ltd 免疫学的測定法
US4812414A (en) * 1987-09-18 1989-03-14 Eastman Kodak Company Immunoreactive reagent particles having tracer, receptor molecules and protein of pI less than 6
ATE195022T1 (de) * 1987-04-27 2000-08-15 Unilever Nv Spezifische bindungstestverfahren
CA2023803C (en) * 1989-08-23 1999-05-18 Takeshi Miyazaki Method for measuring an immunologically active material and apparatus suitable for practicing said method
JP2868900B2 (ja) * 1991-01-11 1999-03-10 クイデル コーポレイション ワンステップ側方流非吸収性アッセイ
US5356782A (en) * 1992-09-03 1994-10-18 Boehringer Mannheim Corporation Analytical test apparatus with on board negative and positive control
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US5712172A (en) * 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use

Also Published As

Publication number Publication date
EP0833157A1 (de) 1998-04-01
EP0833157B1 (de) 2002-11-20
ES2187622T3 (es) 2003-06-16
DE69624920D1 (de) 2003-01-02
DE69624920T2 (de) 2003-09-18
ATE228247T1 (de) 2002-12-15
US6133048A (en) 2000-10-17
AU734197B2 (en) 2001-06-07
US7153681B1 (en) 2006-12-26
AU3684197A (en) 1998-04-02
US20070259446A1 (en) 2007-11-08
CA2215042A1 (en) 1998-03-27
JPH10111292A (ja) 1998-04-28
JP3939403B2 (ja) 2007-07-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDC Discontinued application reinstated
MKEX Expiry

Effective date: 20170911