CA2239053C - Derives d'ethane diphenyle pyridyle utilises comme inhibiteurs de pde iv - Google Patents
Derives d'ethane diphenyle pyridyle utilises comme inhibiteurs de pde iv Download PDFInfo
- Publication number
- CA2239053C CA2239053C CA002239053A CA2239053A CA2239053C CA 2239053 C CA2239053 C CA 2239053C CA 002239053 A CA002239053 A CA 002239053A CA 2239053 A CA2239053 A CA 2239053A CA 2239053 C CA2239053 C CA 2239053C
- Authority
- CA
- Canada
- Prior art keywords
- compound
- pharmaceutically acceptable
- acceptable salt
- independently selected
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Nouveau composé de formule (I) utilisé pour traiter des maladies, y compris l'asthme, par augmentation du niveau d'adénosine-3',5'-monophosphate cyclique (cAMP), cette augmentation étant obtenue par l'inhibition de la phosphodiestérase IV (PDE IV). L'invention se rapporte également à certaines compositions pharmaceutiques et à des méthodes de traitement des maladies par inhibition de la PDE IV, entraînant une augmentation de cAMP, ces méthodes consistant à utiliser des composés de la formule (I).
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US876695P | 1995-12-15 | 1995-12-15 | |
| US60/008,766 | 1995-12-15 | ||
| GB9603723.9 | 1996-02-22 | ||
| GBGB9603723.9A GB9603723D0 (en) | 1996-02-22 | 1996-02-22 | Diphenyl pyridyl derivatives as pde iv inhibitors |
| PCT/CA1996/000838 WO1997022585A1 (fr) | 1995-12-15 | 1996-12-11 | Derives d'ethane diphenyle pyridyle utilises comme inhibiteurs de pde iv |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2239053A1 CA2239053A1 (fr) | 1997-06-26 |
| CA2239053C true CA2239053C (fr) | 2005-04-26 |
Family
ID=56289724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002239053A Expired - Fee Related CA2239053C (fr) | 1995-12-15 | 1996-12-11 | Derives d'ethane diphenyle pyridyle utilises comme inhibiteurs de pde iv |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0873310A1 (fr) |
| JP (1) | JP3468777B2 (fr) |
| CA (1) | CA2239053C (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY123585A (en) * | 2000-03-23 | 2006-05-31 | Merck Canada Inc | Tri-aryl-substituted-ethane pde4 inhibitors. |
| ES2427930T3 (es) | 2001-05-23 | 2013-11-04 | Mitsubishi Tanabe Pharma Corporation | Composición terapéutica para el tratamiento regenerativo de enfermedades de los cartílagos |
-
1996
- 1996-12-11 EP EP96940966A patent/EP0873310A1/fr not_active Withdrawn
- 1996-12-11 JP JP52237697A patent/JP3468777B2/ja not_active Expired - Fee Related
- 1996-12-11 CA CA002239053A patent/CA2239053C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2239053A1 (fr) | 1997-06-26 |
| JP2000501741A (ja) | 2000-02-15 |
| JP3468777B2 (ja) | 2003-11-17 |
| EP0873310A1 (fr) | 1998-10-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5710160A (en) | Diphenyl pyridyl ethane derivatives as PDE IV inhibitors | |
| US5710170A (en) | Tri-aryl ethane derivatives as PDE IV inhibitors | |
| AU732177B2 (en) | Aryl furan derivatives as PDE IV inhibitors | |
| US6204275B1 (en) | PDE IV inhibiting compounds, compositions and methods of treatment | |
| AU707574B2 (en) | Tri-aryl ethane derivatives as PDE IV inhibitors | |
| US6034089A (en) | Aryl thiophene derivatives as PDE IV inhibitors | |
| DE69405497T2 (de) | Styryl-derivate, deren herstellung und verwendung als pde-iv inhibitoren | |
| US6316472B1 (en) | Heterosubstituted pyridine derivatives as PDE 4 inhibitors | |
| US6200993B1 (en) | Heterosubstituted pyridine derivatives as PDE4 inhibitors | |
| CZ291040B6 (cs) | Trisubstituované fenylové deriváty a farmaceutický prostředek s jejich obsahem | |
| US6180650B1 (en) | Heterosubstituted pyridine derivatives as PDE 4 inhibitors | |
| AU732406B2 (en) | Aryl thiophene derivatives as PDE IV inhibitors | |
| CA2239053C (fr) | Derives d'ethane diphenyle pyridyle utilises comme inhibiteurs de pde iv |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |