CA2243657C - Composition pour le traitement de la dysfonction erectile - Google Patents

Composition pour le traitement de la dysfonction erectile Download PDF

Info

Publication number
CA2243657C
CA2243657C CA002243657A CA2243657A CA2243657C CA 2243657 C CA2243657 C CA 2243657C CA 002243657 A CA002243657 A CA 002243657A CA 2243657 A CA2243657 A CA 2243657A CA 2243657 C CA2243657 C CA 2243657C
Authority
CA
Canada
Prior art keywords
carrier
weight
lecithin
mixture
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002243657A
Other languages
English (en)
Other versions
CA2243657A1 (fr
Inventor
John Di Genova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3439755 CANADA Inc
Original Assignee
3439755 CANADA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3439755 CANADA Inc filed Critical 3439755 CANADA Inc
Priority to CA002243657A priority Critical patent/CA2243657C/fr
Publication of CA2243657A1 publication Critical patent/CA2243657A1/fr
Application granted granted Critical
Publication of CA2243657C publication Critical patent/CA2243657C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Un excipient pour utilisation avec des composés vasoactifs pour le traitement de la dysfonction érectile est constitué d'un gel semi-solide à des températures ambiantes tout en existant sous une forme relativement liquide à des températures réduites. L'excipient comprend un mélange d'un composé de lécithine, du palmitate d'isopropyle, de l'acide sorbique, et du gel de pluronic constitué du pluronic et du sorbate de potassium dans une base aqueuse. Un anesthésiant local approprié peut être ajouté à l'excipient. Un applicateur à usage unique, comprenant un distributeur du type à seringue comporte un corps qui contient une dose pharmaceutiquement active d'un composé vasoactif prémélangé dans un excipient tel que décrit ci-dessus.
CA002243657A 1998-07-21 1998-07-21 Composition pour le traitement de la dysfonction erectile Expired - Lifetime CA2243657C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002243657A CA2243657C (fr) 1998-07-21 1998-07-21 Composition pour le traitement de la dysfonction erectile

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002243657A CA2243657C (fr) 1998-07-21 1998-07-21 Composition pour le traitement de la dysfonction erectile

Publications (2)

Publication Number Publication Date
CA2243657A1 CA2243657A1 (fr) 2000-01-21
CA2243657C true CA2243657C (fr) 2003-03-25

Family

ID=4162675

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002243657A Expired - Lifetime CA2243657C (fr) 1998-07-21 1998-07-21 Composition pour le traitement de la dysfonction erectile

Country Status (1)

Country Link
CA (1) CA2243657C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3266458A1 (fr) * 2016-07-05 2018-01-10 Fagron B.V. Procédé et composition et kit pour traiter un dysfonctionnement érectile

Also Published As

Publication number Publication date
CA2243657A1 (fr) 2000-01-21

Similar Documents

Publication Publication Date Title
FI102454B (fi) Menetelmä erektiilisen dysfunktion hoitamiseksi käytettävän koostumuks en valmistamiseksi
EP1026947B1 (fr) Composition et procede de traitement des dyserections
JP4901042B2 (ja) クロニジン製剤
CA2040914C (fr) Traitement des troubles de l'erection
US9005183B2 (en) System and method for treating erectile dysfunction
US7033998B2 (en) Alcohol-free transdermal insulin composition and processes for manufacture and use thereof
KR20010078754A (ko) 통증 경감 방법 및 통증 경감용 경피 조성물
KR19980703052A (ko) 발기 기능장애의 예방 방법 및 키트
JPS63132825A (ja) 血管拡張剤のゲル化軟膏
WO1999038472A2 (fr) Composition de gel de vasodilatation topique et ses methodes d'utilisation et de production
KR20000064392A (ko) 발기부전치료용pge-1함유동결건조된리포좀
US6291528B1 (en) Prostaglandin E1/F2 in combination with prostaglandin F2α for enhancing female sexual arousal
EP1059926A2 (fr) COMBINAISON DE PROSTAGLANDINES E 2?/F 2$g(a)?, DESTINEE AU TRAITEMENT DE L'IMPUISSANCE ET A L'ACCROISSEMENT DE L'EXCITATION SEXUELLE
US7291591B2 (en) Alcohol-free transdermal insulin composition
US5962528A (en) Prostaglandin E2 /F2α combination for treating impotence
CA2243657C (fr) Composition pour le traitement de la dysfonction erectile
JPH0466847B2 (fr)
EP3266458A1 (fr) Procédé et composition et kit pour traiter un dysfonctionnement érectile
US20020103110A1 (en) System and method for rectal administration of medication for treatment of migraines
KR100347883B1 (ko) 국소마취제를 함유한 약용겔제 조성물
RU2198660C2 (ru) Состав и способ лечения нарушения эректильной дисфункции полового члена
Higgins MUSE® drug delivery device for erectile dysfunction
WO2010044094A2 (fr) Composition topique pour traiter un dysfonctionnement érectile
HK40073170B (zh) 尿道内药品剂型和装置
BR102016015716A2 (pt) Método, composição e kit para tratamento da disfunção erétil

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20180723