CA2271440A1 - Traitement de liquides biologiques - Google Patents

Traitement de liquides biologiques Download PDF

Info

Publication number: CA2271440A1
Authority: CA; Canada
Prior art keywords: biological fluid; obtaining; leukocyte; container; blood
Prior art date: 1996-12-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002271440A

Other languages

English (en)

Inventor

Barry Wenz

Judy Angelbeck

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pall Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-12-24

Filing date

1997-12-19

Publication date

1998-07-02

1997-12-19 Application filed by Individual filed Critical Individual

1998-07-02 Publication of CA2271440A1 publication Critical patent/CA2271440A1/fr

Status Abandoned legal-status Critical Current

Links

239000013060 biological fluid Substances 0.000 title claims abstract description 168
238000012545 processing Methods 0.000 title claims abstract description 24
238000000034 method Methods 0.000 claims abstract description 31
230000012953 feeding on blood of other organism Effects 0.000 claims abstract description 16
210000000265 leukocyte Anatomy 0.000 claims description 63
210000004369 blood Anatomy 0.000 claims description 42
239000008280 blood Substances 0.000 claims description 41
239000003634 thrombocyte concentrate Substances 0.000 claims description 33
210000001772 blood platelet Anatomy 0.000 claims description 23
210000003743 erythrocyte Anatomy 0.000 claims description 22
239000006228 supernatant Substances 0.000 claims description 19
239000012530 fluid Substances 0.000 claims description 17
238000004891 communication Methods 0.000 claims description 11
KRADHMIOFJQKEZ-UHFFFAOYSA-N Tri-2-ethylhexyl trimellitate Chemical compound CCCCC(CC)COC(=O)C1=CC=C(C(=O)OCC(CC)CCCC)C(C(=O)OCC(CC)CCCC)=C1 KRADHMIOFJQKEZ-UHFFFAOYSA-N 0.000 claims description 8
239000013049 sediment Substances 0.000 claims description 8
238000010241 blood sampling Methods 0.000 claims description 5
230000000149 penetrating effect Effects 0.000 claims description 5
239000003146 anticoagulant agent Substances 0.000 claims description 3
229940127219 anticoagulant drug Drugs 0.000 claims description 3
239000004014 plasticizer Substances 0.000 claims description 3
239000012503 blood component Substances 0.000 description 26
239000000306 component Substances 0.000 description 26
210000004623 platelet-rich plasma Anatomy 0.000 description 23
241000894006 Bacteria Species 0.000 description 22
238000011176 pooling Methods 0.000 description 22
238000012546 transfer Methods 0.000 description 19
239000000463 material Substances 0.000 description 17
238000011109 contamination Methods 0.000 description 13
210000002381 plasma Anatomy 0.000 description 13
239000000047 product Substances 0.000 description 12
238000003860 storage Methods 0.000 description 10
JNXDCMUUZNIWPQ-UHFFFAOYSA-N trioctyl benzene-1,2,4-tricarboxylate Chemical compound CCCCCCCCOC(=O)C1=CC=C(C(=O)OCCCCCCCC)C(C(=O)OCCCCCCCC)=C1 JNXDCMUUZNIWPQ-UHFFFAOYSA-N 0.000 description 9
230000001580 bacterial effect Effects 0.000 description 8
BJQHLKABXJIVAM-UHFFFAOYSA-N bis(2-ethylhexyl) phthalate Chemical compound CCCCC(CC)COC(=O)C1=CC=CC=C1C(=O)OCC(CC)CCCC BJQHLKABXJIVAM-UHFFFAOYSA-N 0.000 description 8
239000010836 blood and blood product Substances 0.000 description 8
229940125691 blood product Drugs 0.000 description 8
210000004027 cell Anatomy 0.000 description 7
239000003570 air Substances 0.000 description 6
230000002411 adverse Effects 0.000 description 5
239000004800 polyvinyl chloride Substances 0.000 description 5
238000011144 upstream manufacturing Methods 0.000 description 5
MQIUGAXCHLFZKX-UHFFFAOYSA-N Di-n-octyl phthalate Natural products CCCCCCCCOC(=O)C1=CC=CC=C1C(=O)OCCCCCCCC MQIUGAXCHLFZKX-UHFFFAOYSA-N 0.000 description 4
241000700605 Viruses Species 0.000 description 4
239000000654 additive Substances 0.000 description 4
230000000996 additive effect Effects 0.000 description 4
230000003385 bacteriostatic effect Effects 0.000 description 4
239000003795 chemical substances by application Substances 0.000 description 4
230000002147 killing effect Effects 0.000 description 4
239000012528 membrane Substances 0.000 description 4
238000011084 recovery Methods 0.000 description 4
230000004888 barrier function Effects 0.000 description 3
230000000779 depleting effect Effects 0.000 description 3
230000000694 effects Effects 0.000 description 3
238000001914 filtration Methods 0.000 description 3
238000003032 molecular docking Methods 0.000 description 3
BJQHLKABXJIVAM-BGYRXZFFSA-N 1-o-[(2r)-2-ethylhexyl] 2-o-[(2s)-2-ethylhexyl] benzene-1,2-dicarboxylate Chemical compound CCCC[C@H](CC)COC(=O)C1=CC=CC=C1C(=O)OC[C@H](CC)CCCC BJQHLKABXJIVAM-BGYRXZFFSA-N 0.000 description 2
229920012485 Plasticized Polyvinyl chloride Polymers 0.000 description 2
239000003242 anti bacterial agent Substances 0.000 description 2
239000003443 antiviral agent Substances 0.000 description 2
230000000712 assembly Effects 0.000 description 2
238000000429 assembly Methods 0.000 description 2
230000008901 benefit Effects 0.000 description 2
MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 description 2
238000006073 displacement reaction Methods 0.000 description 2
-1 e.g. Substances 0.000 description 2
230000036512 infertility Effects 0.000 description 2
244000005700 microbiome Species 0.000 description 2
238000012986 modification Methods 0.000 description 2
230000004048 modification Effects 0.000 description 2
229920000915 polyvinyl chloride Polymers 0.000 description 2
230000008569 process Effects 0.000 description 2
230000000717 retained effect Effects 0.000 description 2
238000005070 sampling Methods 0.000 description 2
238000013022 venting Methods 0.000 description 2
206010060935 Alloimmunisation Diseases 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
241000192125 Firmicutes Species 0.000 description 1
208000009329 Graft vs Host Disease Diseases 0.000 description 1
206010037660 Pyrexia Diseases 0.000 description 1
241000191963 Staphylococcus epidermidis Species 0.000 description 1
239000012080 ambient air Substances 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
230000000890 antigenic effect Effects 0.000 description 1
229960003405 ciprofloxacin Drugs 0.000 description 1
230000001010 compromised effect Effects 0.000 description 1
208000024908 graft versus host disease Diseases 0.000 description 1
230000028993 immune response Effects 0.000 description 1
230000000977 initiatory effect Effects 0.000 description 1
239000002184 metal Substances 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
235000010446 mineral oil Nutrition 0.000 description 1
239000000203 mixture Substances 0.000 description 1
230000035699 permeability Effects 0.000 description 1
230000001766 physiological effect Effects 0.000 description 1
239000011148 porous material Substances 0.000 description 1
238000004321 preservation Methods 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
230000001012 protector Effects 0.000 description 1
LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical compound C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 description 1
150000007660 quinolones Chemical class 0.000 description 1
238000007789 sealing Methods 0.000 description 1
239000000344 soap Substances 0.000 description 1
230000007704 transition Effects 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
210000003462 vein Anatomy 0.000 description 1
230000035899 viability Effects 0.000 description 1
238000009736 wetting Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
- A61M1/0218—Multiple bag systems for separating or storing blood components with filters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
- B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
- A61M2202/0439—White blood cells; Leucocytes
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2221/00—Applications of separation devices
- B01D2221/10—Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues

Landscapes

Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Biomedical Technology (AREA)
Anesthesiology (AREA)
Vascular Medicine (AREA)
Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
External Artificial Organs (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

CA002271440A 1996-12-24 1997-12-19 Traitement de liquides biologiques Abandoned CA2271440A1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US3414596P	1996-12-24	1996-12-24
US60/034,145		1996-12-24
PCT/US1997/023558 WO1998028057A1 (fr)	1996-12-24	1997-12-19	Traitement de liquides biologiques

Publications (1)

Publication Number	Publication Date
CA2271440A1 true CA2271440A1 (fr)	1998-07-02

Family

ID=21874592

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002271440A Abandoned CA2271440A1 (fr)	1996-12-24	1997-12-19	Traitement de liquides biologiques

Country Status (5)

Country	Link
EP (1)	EP0949946A4 (fr)
JP (1)	JP2001507353A (fr)
AU (1)	AU736156B2 (fr)
CA (1)	CA2271440A1 (fr)
WO (1)	WO1998028057A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6592613B1 (en)	1998-01-16	2003-07-15	Terumo Kabushiki Kaisha	Blood collecting apparatus and blood collecting method using blood collecting apparatus
US7025877B1 (en)	1999-06-03	2006-04-11	Baxter International Inc.	Processing set for processing and treating a biological fluid
US7445756B2 (en)	1999-06-03	2008-11-04	Fenwal, Inc.	Fluid processing sets and organizers for the same
US6387086B2 (en)	1999-07-29	2002-05-14	Baxter International Inc.	Blood processing set including an integrated blood sampling system
CA2373689A1 (fr)	1999-07-29	2001-02-08	Thomas W. Coneys	Support de tube de prelevement destine a un systeme de prelevement de sang
US7435231B2 (en)	1999-07-29	2008-10-14	Fenwal, Inc.	Biological sample device receiver
WO2001032828A2 (fr) *	1999-10-29	2001-05-10	Pall Corporation	Traitement de fluide biologique
JP2002173433A (ja)	2000-12-04	2002-06-21	Terumo Corp	白血球除去血液製剤の調製方法および血液セット
US7264608B2 (en) *	2001-12-05	2007-09-04	Fenwal, Inc.	Manual processing systems and methods for providing blood components conditioned for pathogen inactivation
EP1455860B1 (fr)	2001-12-10	2011-08-31	CaridianBCT, Inc.	Procedes de leucoreduction de globules rouges
JP2005524445A (ja) *	2002-05-03	2005-08-18	ガンブロ　　インコーポレーテッド	血液製剤中のバクテリアを検出する装置並びに方法
ITRM20030467A1 (it) *	2003-10-10	2005-04-11	Advance Holdings Ltd	Contenitore monouso per la centrifugazione ed il trattamento di un materiale biologico fluido.
CA2761603C (fr) *	2009-05-14	2018-06-05	Biotechnology Institute, I Mas D, S.L.	Procede de preparation d'au moins un compose a partir de sang, et dispositif d'extraction en vue d'une utilisation dans l'execution de ce procede
US8535241B2 (en)	2011-10-13	2013-09-17	Magnolia Medical Technologies, Inc.	Fluid diversion mechanism for bodily-fluid sampling
US9022950B2 (en)	2012-05-30	2015-05-05	Magnolia Medical Technologies, Inc.	Fluid diversion mechanism for bodily-fluid sampling
US9060724B2 (en)	2012-05-30	2015-06-23	Magnolia Medical Technologies, Inc.	Fluid diversion mechanism for bodily-fluid sampling
WO2014022275A1 (fr)	2012-08-01	2014-02-06	Magnolia Medical Technologies, Inc.	Mécanisme de déviation de fluide pour prélèvement de fluide corporel
WO2014058945A1 (fr)	2012-10-11	2014-04-17	Bullington Gregory J	Systèmes et méthodes d'administration d'un fluide à un patient en réduisant la contamination
DE102012022826B4 (de) *	2012-11-22	2022-10-13	Hubert Wöllenstein	Verfahren zur Herstellung eines gepoolten Thrombozytenkonzentrats
CN109171766A (zh)	2012-11-30	2019-01-11	木兰医药技术股份有限公司	体液隔绝装置和使用体液隔绝装置隔绝体液的方法
US10772548B2 (en)	2012-12-04	2020-09-15	Magnolia Medical Technologies, Inc.	Sterile bodily-fluid collection device and methods
IL303591B2 (en)	2012-12-04	2025-11-01	Magnolia Medical Technologies Inc	Sterile bodily-fluid collection device and methods
US10376627B2 (en)	2014-03-24	2019-08-13	Fenwal, Inc.	Flexible biological fluid filters
US9968738B2 (en)	2014-03-24	2018-05-15	Fenwal, Inc.	Biological fluid filters with molded frame and methods for making such filters
US10159778B2 (en)	2014-03-24	2018-12-25	Fenwal, Inc.	Biological fluid filters having flexible walls and methods for making such filters
US9782707B2 (en)	2014-03-24	2017-10-10	Fenwal, Inc.	Biological fluid filters having flexible walls and methods for making such filters
US9796166B2 (en)	2014-03-24	2017-10-24	Fenwal, Inc.	Flexible biological fluid filters
EP3329948B1 (fr) *	2016-12-01	2023-09-06	Fenwal, Inc.	Dispositif de groupement de composants sanguins, système et procédé
JP7273807B2 (ja)	2017-06-09	2023-05-15	マグノリアメディカルテクノロジーズ，インコーポレイテッド	流体制御デバイス及びそれを使用する方法
EP3681384B1 (fr)	2017-09-12	2022-12-28	Magnolia Medical Technologies, Inc.	Un système
WO2020163744A1 (fr)	2019-02-08	2020-08-13	Magnolia Medical Technologies, Inc.	Dispositifs et procédés pour la collecte et la distribution de fluide corporel

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2058577A5 (fr) *	1969-09-17	1971-05-28	Medicoplast Labor
US4280497A (en) *	1979-10-09	1981-07-28	Cutter Laboratories, Inc.	Container for platelet storage
US4670013A (en) *	1982-12-27	1987-06-02	Miles Laboratories, Inc.	Container for blood and blood components
SE460697B (sv) *	1988-03-31	1989-11-13	Anita Maria Christina Hansby	Blodtappningsanordning foer blodgivning samt anvaendning av anordningen
DE68902698C5 (de) *	1988-06-23	2005-07-14	Asahi Medical Co. Ltd.	Verfahren zur Trennung von Blut in Blutkomponenten und Einheit zur Trennung von Blutkomponenten.
US5100564A (en) *	1990-11-06	1992-03-31	Pall Corporation	Blood collection and processing system
CA2072378C (fr) *	1991-11-21	2000-12-26	Vlado Ivan Matkovich	Methode d'assemblage de plusieurs receptables contenant un fluide biologique
US5549834A (en) *	1991-12-23	1996-08-27	Baxter International Inc.	Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
CA2083075A1 (fr) *	1992-06-10	1993-12-11	Vlado I. Matkovich	Systeme pour le traitement du materiau de la zone de transition

1997
- 1997-12-19 EP EP97954595A patent/EP0949946A4/fr not_active Withdrawn
- 1997-12-19 JP JP52899698A patent/JP2001507353A/ja active Pending
- 1997-12-19 AU AU59008/98A patent/AU736156B2/en not_active Ceased
- 1997-12-19 WO PCT/US1997/023558 patent/WO1998028057A1/fr not_active Ceased
- 1997-12-19 CA CA002271440A patent/CA2271440A1/fr not_active Abandoned

Also Published As

Publication number	Publication date
AU736156B2 (en)	2001-07-26
EP0949946A1 (fr)	1999-10-20
AU5900898A (en)	1998-07-17
EP0949946A4 (fr)	2001-02-14
JP2001507353A (ja)	2001-06-05
WO1998028057A1 (fr)	1998-07-02

Legal Events

Date	Code	Title	Description
2002-05-13	EEER	Examination request
2006-12-19	FZDE	Discontinued

Publication	Publication Date	Title
AU736156B2 (en)	2001-07-26	Biological fluid processing
EP0540732B1 (fr)	1995-11-08	Systemes et procedes permettant d'eliminer les substances indesirees des cellules du sang
US5089146A (en)	1992-02-18	Pre-storage filtration of platelets
US5364526A (en)	1994-11-15	System for processing separate containers of biological fluid
US5236716A (en)	1993-08-17	Platelets concentrate with low white blood cells content
EP0540734B1 (fr)	1997-01-22	Systemes et procedes destines a eliminer des materiaux non desires de cellules sanguines
US5738796A (en)	1998-04-14	Method for separating components from a biological fluid
US5472621A (en)	1995-12-05	Method for treating transition zone material
US5512187A (en)	1996-04-30	Methods for processing red cell products for long term storage free of microorganisms
CA2137797C (fr)	2003-01-07	Systeme de traitement du materiel present dans une zone de transition
US6358420B2 (en)	2002-03-19	Blood collection method employing an air venting blood sample tube
CA2143680A1 (fr)	1994-03-17	Processus et appareil permettant de retirer les liquides indesires des produits sanguins traites
CA2405443A1 (fr)	2001-10-11	Systemes et procedes pour collecter des composants sanguins sans leucocytes, comprenant le plasma exempt ou pratiquement exempt d'especes sanguines cellulaires
EP0623045B1 (fr)	1997-04-23	Methode de filtrage d'un fluide corporel mettant en uvre une poche de rincage
WO2000007642A1 (fr)	2000-02-17	Systeme de traitement de fluides biologiques
JP2013203659A (ja)	2013-10-07	血液処理フィルタ及び血液回路
HK1126378B (en)	2014-06-20	Prechargeable fluid filtration method and apparatus
HK1126378A1 (en)	2009-09-04	Prechargeable fluid filtration method and apparatus