CA2276018C - Chambre de pulverisation avec sechoir - Google Patents

Chambre de pulverisation avec sechoir Download PDF

Info

Publication number
CA2276018C
CA2276018C CA002276018A CA2276018A CA2276018C CA 2276018 C CA2276018 C CA 2276018C CA 002276018 A CA002276018 A CA 002276018A CA 2276018 A CA2276018 A CA 2276018A CA 2276018 C CA2276018 C CA 2276018C
Authority
CA
Canada
Prior art keywords
spray
gas
nebulizer
droplets
sheath gas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002276018A
Other languages
English (en)
Other versions
CA2276018A1 (fr
Inventor
John B. French
Bernard Etkin
Raymond Jong
Guy Legere
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revvity Health Sciences Inc
Original Assignee
MDS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/974,957 external-priority patent/US5969352A/en
Application filed by MDS Inc filed Critical MDS Inc
Publication of CA2276018A1 publication Critical patent/CA2276018A1/fr
Application granted granted Critical
Publication of CA2276018C publication Critical patent/CA2276018C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0468—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample
    • H01J49/049—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components with means for heating or cooling the sample with means for applying heat to desorb the sample; Evaporation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0431—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples
    • H01J49/0445—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol
    • H01J49/045—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components for liquid samples with means for introducing as a spray, a jet or an aerosol with means for using a nebulising gas, i.e. pneumatically assisted
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/105—Ion sources; Ion guns using high-frequency excitation, e.g. microwave excitation, Inductively Coupled Plasma [ICP]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Electron Tubes For Measurement (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne une chambre de pulvérisation permettant de produire un échantillon pour un analyseur susceptible de contenir une torche à plasma. Dans la chambre, un gaz de gainage chauffé est introduit dans la zone périphérique de pulvérisation entourant le jet de pulvérisation et au voisinage de la naissance du jet de pulvérisation, ce qui entraîne une réduction de la taille des gouttelettes qui sont recyclées, et a pour effet de réduire les phénomènes d'agglomération des gouttelettes et de favoriser un séchage rapide du produit de pulvérisation. De préférence, la totalité du solvant de pulvérisation s'évapore au niveau d'une chambre très courte, ce qui permet de réduire la quantité du produit de pulvérisation recyclée. L'ensemble du flux combiné des particules séchées issues de la pulvérisation, du gaz de nébulisation et du gaz de gainage est dirigé dans la torche. Dans un mode de réalisation, la partie centrale du flux combiné est dirigée vers la torche et la partie périphérique du flux combiné est évacuée de manière canalisé. Dans un autre mode de réalisation, le solvant aqueux de pulvérisation s'évapore totalement avant de quitter la chambre de pulvérisation, le flux combiné étant dirigé à travers un séchoir à membrane avant d'atteindre la torche, de façon à éliminer du flux la majeure partie de la vapeur d'eau et à réduire la vapeur d'eau venant charger la torche.
CA002276018A 1997-01-03 1997-12-22 Chambre de pulverisation avec sechoir Expired - Lifetime CA2276018C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77859397A 1997-01-03 1997-01-03
US08/778,593 1997-01-03
US08/974,957 US5969352A (en) 1997-01-03 1997-11-20 Spray chamber with dryer
US08/974,957 1997-11-20
PCT/CA1997/001007 WO1998029896A1 (fr) 1997-01-03 1997-12-22 Chambre de pulverisation avec sechoir

Publications (2)

Publication Number Publication Date
CA2276018A1 CA2276018A1 (fr) 1998-07-09
CA2276018C true CA2276018C (fr) 2004-11-23

Family

ID=27119475

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002276018A Expired - Lifetime CA2276018C (fr) 1997-01-03 1997-12-22 Chambre de pulverisation avec sechoir

Country Status (5)

Country Link
EP (1) EP1012871A1 (fr)
JP (1) JP3831415B2 (fr)
AU (1) AU5474598A (fr)
CA (1) CA2276018C (fr)
WO (1) WO1998029896A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7045015B2 (en) 1998-09-30 2006-05-16 Optomec Design Company Apparatuses and method for maskless mesoscale material deposition
JP3902380B2 (ja) * 2000-05-19 2007-04-04 エスアイアイ・ナノテクノロジー株式会社 Ｉｃｐ分析装置
US6989529B2 (en) * 2001-07-03 2006-01-24 Varian Australia Pty Ltd. Plasma torch
US7479630B2 (en) * 2004-03-25 2009-01-20 Bandura Dmitry R Method and apparatus for flow cytometry linked with elemental analysis
US7265362B2 (en) 2004-02-06 2007-09-04 Micromass Uk Limited Mass spectrometer
DE202005001632U1 (de) * 2004-02-06 2005-06-02 Micromass Uk Ltd. Massenspektrometer
US7294841B2 (en) 2004-02-06 2007-11-13 Micromass Uk Limited Mass spectrometer
US7938341B2 (en) * 2004-12-13 2011-05-10 Optomec Design Company Miniature aerosol jet and aerosol jet array
US7674671B2 (en) 2004-12-13 2010-03-09 Optomec Design Company Aerodynamic jetting of aerosolized fluids for fabrication of passive structures
TWI482662B (zh) 2007-08-30 2015-05-01 阿普托麥克股份有限公司 機械上一體式及緊密式耦合之列印頭以及噴霧源
JP4982900B2 (ja) * 2008-07-02 2012-07-25 独立行政法人産業技術総合研究所 脱溶媒機能付き誘導結合プラズマトーチ
KR200457166Y1 (ko) 2008-12-16 2011-12-07 문무 주식회사 분말 건조 장치
US9190253B2 (en) 2010-02-26 2015-11-17 Perkinelmer Health Sciences, Inc. Systems and methods of suppressing unwanted ions
JP5792203B2 (ja) 2010-02-26 2015-10-07 パーキンエルマー・ヘルス・サイエンシーズ・インコーポレイテッドＰｅｒｋｉｎｅｌｍｅｒ Ｈｅａｌｔｈ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． イオンを抑制させたプラズマ質量分析器
SG10201501031YA (en) 2010-02-26 2015-04-29 Perkinelmer Health Sci Inc Fluid chromatography injectors and injector inserts
GB201216412D0 (en) * 2012-09-14 2012-10-31 Shimadzu Corp Apparatus for providing gaseous sample ions/molecules and a corresponding method
JP2014211377A (ja) * 2013-04-19 2014-11-13 株式会社堀場製作所 粒子分析装置
WO2016130709A1 (fr) 2015-02-10 2016-08-18 Optomec, Inc. Fabrication de structures tridimensionnelles par durcissement en vol d'aérosols
JP6048552B1 (ja) 2015-08-21 2016-12-21 株式会社 イアス オンライン移送した分析試料の分析システム
EP3459323A4 (fr) 2016-05-18 2020-01-01 Perkinelmer Health Sciences Canada, Inc Chambres de pulvérisation et leurs procédés d'utilisation
KR102288662B1 (ko) * 2017-05-12 2021-08-10 가부시키가이샤 사무코 스프레이 챔버, 시료 안개화 도입 장치, 분석 장치 및 시료 중의 성분 분석 방법
EP3723909B1 (fr) 2017-11-13 2023-10-25 Optomec, Inc. Dispositif d'arrêt de flux d'aérosol
EP3921086A4 (fr) 2019-02-04 2022-11-02 Glass Expansion Pty. Limited Nébuliseur analytique
TW202247905A (zh) 2021-04-29 2022-12-16 美商阿普托麥克股份有限公司 用於氣溶膠噴射裝置之高可靠性鞘護輸送路徑
CN116726519A (zh) * 2023-06-14 2023-09-12 广东省麦思科学仪器创新研究院 雾化气细胞干燥装置和质谱流式细胞仪

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990740A (en) * 1989-03-06 1991-02-05 The Dow Chemical Company Intra-microspray ICP torch
US4958529A (en) * 1989-11-22 1990-09-25 Vestec Corporation Interface for coupling liquid chromatography to solid or gas phase detectors
US5122670A (en) * 1991-05-17 1992-06-16 Finnigan Corporation Multilayer flow electrospray ion source using improved sheath liquid
CA2062629C (fr) * 1992-03-10 1999-06-15 John Barry French Appareil et methode d'introduction d'echantillon liquide
EP0560537A1 (fr) * 1992-03-10 1993-09-15 Mds Health Group Limited Dispositif et méthode pour l'introduction d'échantillons liquides

Also Published As

Publication number Publication date
AU5474598A (en) 1998-07-31
CA2276018A1 (fr) 1998-07-09
JP2001507449A (ja) 2001-06-05
EP1012871A1 (fr) 2000-06-28
WO1998029896A1 (fr) 1998-07-09
JP3831415B2 (ja) 2006-10-11

Similar Documents

Publication Publication Date Title
US5969352A (en) Spray chamber with dryer
EP1012871A1 (fr) Chambre de pulverisation avec sechoir
EP1377822B1 (fr) Procede et dispositif servant a ioniser un analyte et echantillon de source ionique utilisee a cet effet
US4990740A (en) Intra-microspray ICP torch
CA2062629C (fr) Appareil et methode d'introduction d'echantillon liquide
US6759650B2 (en) Method of and apparatus for ionizing an analyte and ion source probe for use therewith
EP0455892B1 (fr) Générateur d'aérosol monodispersé pour l'utilisation en spectrométrie infrarouge
JP3925000B2 (ja) 噴霧器及びそれを用いた分析装置
US4935624A (en) Thermal-assisted electrospray interface (TAESI) for LC/MS
US5412208A (en) Ion spray with intersecting flow
US9804183B2 (en) Apparatus and method for liquid sample introduction
CA2016129C (fr) Generateur d'aerosols monodisperses pour la spectrometrie infrarouge
GB2226882A (en) Coupling liquid chromatography units to solid or gas phase detectors
EP1597574B1 (fr) Détecteur de dispersion de lumière à l'évaporation
WO1999002957A1 (fr) Compteur de noyaux de condensation a stabilisation de vapeur et recuperation de fluide de travail
US5175433A (en) Monodisperse aerosol generator for use with infrared spectrometry
CN114994162B (zh) 基于液滴辅助电离技术的气溶胶化学组分测量系统和方法
AU2006276119A1 (en) Focused droplet nebulizer for evaporative light scattering detector
EP0560537A1 (fr) Dispositif et méthode pour l'introduction d'échantillons liquides
US6709632B2 (en) ICP analyzer
Gomes et al. Continuous emission monitoring of metal aerosol concentrations in atmospheric air
JP2005026159A (ja) 質量分析装置
JPH05180802A (ja) 液体サンプルを分析するための方法及び装置
JPS5840699B2 (ja) 液体クロマトグラフと質量分析計とを結合した分析装置
JPH04155239A (ja) 赤外線分光法に用いるための単分散エーロゾル発生装置

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20171222