CA2288221A1 - Diagnostic et traitement de troubles lies a la phosphatase ou a la kinase - Google Patents

Diagnostic et traitement de troubles lies a la phosphatase ou a la kinase Download PDF

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Publication number
CA2288221A1
CA2288221A1 CA002288221A CA2288221A CA2288221A1 CA 2288221 A1 CA2288221 A1 CA 2288221A1 CA 002288221 A CA002288221 A CA 002288221A CA 2288221 A CA2288221 A CA 2288221A CA 2288221 A1 CA2288221 A1 CA 2288221A1
Authority
CA
Canada
Prior art keywords
seq
ptp04
protein
polypeptide
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002288221A
Other languages
English (en)
Inventor
Greg D. Plowman
Douglas Clary
Bahija Jallal
Elior Peles
Susan Onrust
Dave Markby
Sara A. Courtneidge
Harald App
Terence H. Hui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sugen LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2288221A1 publication Critical patent/CA2288221A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des phosphatases et des kinases, des acides nucléiques codant de tels polypeptides, des cellules, des tissus et des animaux contenant de tels acides nucléiques, des anticorps dirigés contre de tels polypeptides, des essais utilisant de tels polypeptides et des procédés se rapportant à ce qui a été énoncé précédemment. L'invention concerne également des procédés permettant de traiter, de diagnostiquer et de rechercher les affections ou états concernés par les phosphatases et les kinases et caractérisés par une interaction anormale entre une phosphatase ou une kinase et son partenaire de liaison.
CA002288221A 1997-04-28 1998-04-27 Diagnostic et traitement de troubles lies a la phosphatase ou a la kinase Abandoned CA2288221A1 (fr)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US4442897P 1997-04-28 1997-04-28
US60/044,428 1997-04-28
US4722297P 1997-05-20 1997-05-20
US60/047,222 1997-05-20
US4947797P 1997-06-11 1997-06-11
US4975697P 1997-06-11 1997-06-11
US60/049,756 1997-06-11
US60/049,477 1997-06-11
US4991497P 1997-06-18 1997-06-18
US60/049,914 1997-06-18
US6359597P 1997-10-23 1997-10-23
US60/063,595 1997-10-23
PCT/US1998/008439 WO1998049317A2 (fr) 1997-04-28 1998-04-27 Diagnostic et traitement de troubles lies a la phosphatase ou a la kinase

Publications (1)

Publication Number Publication Date
CA2288221A1 true CA2288221A1 (fr) 1998-11-05

Family

ID=27556472

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002288221A Abandoned CA2288221A1 (fr) 1997-04-28 1998-04-27 Diagnostic et traitement de troubles lies a la phosphatase ou a la kinase

Country Status (5)

Country Link
EP (1) EP0979288A2 (fr)
JP (1) JP2002513289A (fr)
AU (1) AU7260098A (fr)
CA (1) CA2288221A1 (fr)
WO (1) WO1998049317A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2220853A1 (fr) * 1998-01-16 1999-07-16 Hsc Research And Development Limited Partnership Tyrosine phosphatase pour tissus lymphoides humains
WO2000063392A1 (fr) * 1999-04-16 2000-10-26 Kyowa Hakko Kogyo Co., Ltd. Nouvelle tyrosine phosphatase
EP1046715A1 (fr) * 1999-04-23 2000-10-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Interaction de la protéine vasculaire endothelial tyrosine phosphatase et le récepteur Tie-2 d'angiopoietine
JP2003520049A (ja) * 2000-01-18 2003-07-02 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒトタンパク質であるチロシンホスファターゼのポリヌクレオチド、ポリペプチド、および抗体
WO2002042435A2 (fr) * 2000-11-27 2002-05-30 Bayer Aktiengesellschaft Regulation de la tyrosine phosphatase humaine
ES2263862T3 (es) * 2003-03-07 2006-12-16 Istituto Nazionale Per Lo Studio E La Cura Dei Tumori Ensayo de quinasa de linfoma anaplasico, sus reactivos y composiciones.
EP3006039B1 (fr) 2004-03-02 2021-01-06 Acceleron Pharma Inc. Alk7 polypeptides pour stimuler la perte de graisse
WO2007037532A1 (fr) * 2005-09-30 2007-04-05 Link Genomics, Inc. Application therapeutique ou diagnostique du gene srms
EP4217378A4 (fr) * 2020-10-08 2025-02-26 The Trustees Of Dartmouth College Méthodes et agents pour le traitement, la prévention, le diagnostic et l'évaluation d'une thérapie pour des états fibrotiques auto-immuns et inflammatoires

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294538A (en) * 1991-11-18 1994-03-15 Cold Spring Harbor Labs. Method of screening for antimitotic compounds using the CDC25 tyrosine phosphatase
JPH09510861A (ja) * 1993-09-01 1997-11-04 ザ・ルドウィッグ・インスティチュート・フォー・キャンサー・リサーチ 新規な蛋白質チロシンホスファターゼに対するヌクレオチド配列の一次構造および機能性発現
US5830648A (en) * 1995-05-05 1998-11-03 Sugen, Inc. Assay and method for transcript imaging

Also Published As

Publication number Publication date
JP2002513289A (ja) 2002-05-08
AU7260098A (en) 1998-11-24
EP0979288A2 (fr) 2000-02-16
WO1998049317A3 (fr) 1999-02-25
WO1998049317A2 (fr) 1998-11-05

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued