CA2302819A1 - Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles - Google Patents

Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles Download PDF

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Publication number
CA2302819A1
CA2302819A1 CA002302819A CA2302819A CA2302819A1 CA 2302819 A1 CA2302819 A1 CA 2302819A1 CA 002302819 A CA002302819 A CA 002302819A CA 2302819 A CA2302819 A CA 2302819A CA 2302819 A1 CA2302819 A1 CA 2302819A1
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CA
Canada
Prior art keywords
chlorine
agonist
treating sensitive
receptor associated
substance
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Granted
Application number
CA002302819A
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English (en)
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CA2302819C (fr
Inventor
Lionel Breton
Olivier De Lacharriere
Isabelle Nonotte
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LOreal SA
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Individual
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Publication of CA2302819A1 publication Critical patent/CA2302819A1/fr
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Publication of CA2302819C publication Critical patent/CA2302819C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63—Steroids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/005—Preparations for sensitive skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention se rapporte à l'utilisation d'une ou plusieurs substances agonistes d'un ou plusieurs récepteurs associés à un canal chlore ou à un canal potassium dans une composition cosmétique et/ou dermatologique, pour traiter les peaux sensibles et plus spécialement pour supprimer les démangeaisons, les prurits, les tiraillements, les picotements et/ou les érythèmes. La substance agoniste est en particulier la taurine, l'acide gammaamino-butyrique (GABA), l'isoguvacine, l'acide isonipécotique, la 4,5,6,7tétrahydroisoxazolo-(5,4-c)pyridin-3(2H)-one, les benzodiazépines, les stéroïdes, le cromakalim, le pinacidil, le nicorandil et le minoxidil.
CA002302819A 1997-09-01 1998-08-27 Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles Expired - Fee Related CA2302819C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9710853A FR2767692B1 (fr) 1997-09-01 1997-09-01 Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles
FR97/10853 1997-09-01
PCT/FR1998/001861 WO1999011238A1 (fr) 1997-09-01 1998-08-27 Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles

Publications (2)

Publication Number Publication Date
CA2302819A1 true CA2302819A1 (fr) 1999-03-11
CA2302819C CA2302819C (fr) 2006-04-18

Family

ID=9510644

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002302819A Expired - Fee Related CA2302819C (fr) 1997-09-01 1998-08-27 Utilisation d'une substance agoniste d'un recepteur associe a un canal chlore ou potassique dans le traitement des peaux sensibles

Country Status (6)

Country Link
US (1) US6572848B1 (fr)
EP (1) EP1009379A1 (fr)
JP (1) JP2001514206A (fr)
CA (1) CA2302819C (fr)
FR (1) FR2767692B1 (fr)
WO (1) WO1999011238A1 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958976A (en) * 1997-09-19 1999-09-28 E-L Management Corp. Composition and method for reducing stinging in skin
AU4841700A (en) 1999-05-12 2000-11-21 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
FR2826267B1 (fr) * 2001-06-26 2005-02-25 Oreal Composition cosmetique ou dermatologique comprenant une association entre un compose inhibiteur de l'elastase de la famille des n-acylaminoamides et au moins un agent myorelaxant
WO2003053466A1 (fr) * 2001-12-13 2003-07-03 Shiseido Company, Ltd. Accelerateurs de reparation de la fonction barriere de la peau
FR2879450B1 (fr) * 2004-12-20 2007-02-09 Oreal Antagonistes des recepteurs peripheriques des benzodiazepines pour le traitement des peaux seches
WO2006067327A2 (fr) * 2004-12-20 2006-06-29 L'oreal Antagonistes des recepteurs peripheriques des benzodiazepines pour le traitement des peaux seches
FR2883177B1 (fr) * 2005-03-15 2008-01-25 Oreal Utilisation d'agrnets tels que des donneurs ou liberateurs non polymeriques de monoxyde d'azote pour repulper et/ou colorer naturellement les levres
FR2883170A1 (fr) * 2005-03-15 2006-09-22 Oreal Utilisation d'agents tels que des donneurs ou liberateurs non polymeriques de monoxyde d'azote pour colorer naturellement la peau
FR2883171B1 (fr) * 2005-03-15 2007-05-11 Oreal Utilisation d'agents tels que des donneurs ou liberateurs non polymeriques de monoxyde d'azote pour diminuer les poches et/ou les cernes perioculaires
WO2006097348A1 (fr) * 2005-03-15 2006-09-21 L'oreal Utilisation d’agents comme les donneurs d’oxyde nitrique non polymeriques pour rendre les levres a nouveau charnues et/ou colorer les levres
US20110263710A1 (en) * 2010-01-25 2011-10-27 Moskowitz Michael H Transepithelial methods of using gamma aminobutyric acid compositions for pain relief
WO2015117024A1 (fr) 2014-01-31 2015-08-06 Mayo Foundation For Medical Education And Research Nouveaux agents thérapeutiques pour le traitement du glaucome
BR112018015386A2 (pt) 2016-01-27 2019-03-19 Universität Zürich uso de moduladores de receptor gabaa para tratamento de prurido
WO2019226820A1 (fr) 2018-05-22 2019-11-28 Neurocycle Therapeutics, Inc. Composés modulateurs allostériques positifs gabaa pour le traitement du prurit et/ou de la dermatite
AU2020403144A1 (en) 2019-12-12 2022-07-14 Mayo Foundation For Medical Education And Research Controlled-delivery cromakalim prodrugs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2273514A1 (fr) * 1974-06-06 1976-01-02 Orlane Produit cosmetique ayant une action adoucissante sur la peau
JPS63150209A (ja) * 1986-12-15 1988-06-22 Kanebo Ltd 皮膚化粧料
IT1223321B (it) * 1987-10-23 1990-09-19 Maria Curti Composizioni cosmetiche
US4937234A (en) * 1988-08-10 1990-06-26 Fahim Mostafa S Minerals in bioavailable form
ATE146079T1 (de) * 1990-05-31 1996-12-15 Allergan Inc Verwendung von antagonisten des plättchen- aktivierenden faktors bei pruritus
JPH0578243A (ja) * 1990-12-11 1993-03-30 Shiseido Co Ltd 鎮痒剤及び鎮痒組成物
ES2073286T3 (es) * 1991-02-06 1995-08-01 Beiersdorf Ag Productos cosmeticos estables.
DE4328871A1 (de) * 1993-08-27 1995-03-02 Beiersdorf Ag Mittel gegen empfindliche, hyperreaktive Hautzustände, atopische Dermatiden, Pruritus, Psoriasis Prurigo, Photodermatosen und Ichthyosis
RU2080854C1 (ru) * 1994-05-30 1997-06-10 Самсонов Владимир Николаевич Средство, обладающее регенеративной активностью
DE69529043T2 (de) * 1994-09-30 2003-05-08 L'oreal S.A., Paris Verwendung von einem Agonisten eines mit einem Chloridkanal assozierten Rezeptors zur Behandlung von Hautfalten
JPH08217695A (ja) * 1995-02-10 1996-08-27 Pola Chem Ind Inc 皮膚外用剤
US5968528A (en) * 1997-05-23 1999-10-19 The Procter & Gamble Company Skin care compositions
AU754680B2 (en) * 1997-08-21 2002-11-21 Johnson & Johnson Consumer Companies, Inc. Use of 17-alpha-estradiol for the treatment of aged or sundamaged skin and/or skin atrophy

Also Published As

Publication number Publication date
CA2302819C (fr) 2006-04-18
WO1999011238A1 (fr) 1999-03-11
EP1009379A1 (fr) 2000-06-21
FR2767692B1 (fr) 2000-03-03
US6572848B1 (en) 2003-06-03
JP2001514206A (ja) 2001-09-11
FR2767692A1 (fr) 1999-03-05

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