CA2304823A1 - Regulation de l'expression genique - Google Patents

Regulation de l'expression genique Download PDF

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Publication number
CA2304823A1
CA2304823A1 CA002304823A CA2304823A CA2304823A1 CA 2304823 A1 CA2304823 A1 CA 2304823A1 CA 002304823 A CA002304823 A CA 002304823A CA 2304823 A CA2304823 A CA 2304823A CA 2304823 A1 CA2304823 A1 CA 2304823A1
Authority
CA
Canada
Prior art keywords
nucleic acid
gene
scl
isolated nucleic
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002304823A
Other languages
English (en)
Inventor
Angus Mcleod Sinclair
Maria Jose Sanchez
James Gilbert
Jeremy Fordham
Anthony Richard Green
Berthold Gottgens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cambridge University Technical Services Ltd CUTS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2304823A1 publication Critical patent/CA2304823A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention porte sur des isolats d'acide nucléique qui possèdent un élément régulateur du gène SCL, l'isolat étant dépourvu de séquence codant SCL et/ou de promoteur pour le gène SCL. L'élément régulateur peut modifier la transcription à partir d'un gène SCL si le gène est lié de manière fonctionnelle à l'élément.
CA002304823A 1997-09-26 1998-09-28 Regulation de l'expression genique Abandoned CA2304823A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9720533.0A GB9720533D0 (en) 1997-09-26 1997-09-26 Regulation of gene expression
GB9720533.0 1997-09-26
PCT/GB1998/002914 WO1999016782A2 (fr) 1997-09-26 1998-09-28 Regulation de l'expression genique

Publications (1)

Publication Number Publication Date
CA2304823A1 true CA2304823A1 (fr) 1999-04-08

Family

ID=10819709

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002304823A Abandoned CA2304823A1 (fr) 1997-09-26 1998-09-28 Regulation de l'expression genique

Country Status (4)

Country Link
AU (1) AU9179198A (fr)
CA (1) CA2304823A1 (fr)
GB (1) GB9720533D0 (fr)
WO (1) WO1999016782A2 (fr)

Also Published As

Publication number Publication date
WO1999016782A3 (fr) 1999-05-20
WO1999016782A2 (fr) 1999-04-08
GB9720533D0 (en) 1997-11-26
AU9179198A (en) 1999-04-23

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Legal Events

Date Code Title Description
FZDE Discontinued