CA2305016A1 - Proteinase de degradation de la proteine de complement humain c3, tiree du streptococcus pneumoniae - Google Patents
Proteinase de degradation de la proteine de complement humain c3, tiree du streptococcus pneumoniae Download PDFInfo
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- CA2305016A1 CA2305016A1 CA002305016A CA2305016A CA2305016A1 CA 2305016 A1 CA2305016 A1 CA 2305016A1 CA 002305016 A CA002305016 A CA 002305016A CA 2305016 A CA2305016 A CA 2305016A CA 2305016 A1 CA2305016 A1 CA 2305016A1
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-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
Cette invention se rapporte à l'identification et à l'utilisation d'une famille de protéinases dégradant la protéine de complément humain C3, qui sont exprimées par S. Pneumoniae. Une telle protéinase possède un poids moléculaire compris entre 15 kD environ et 25 kD environ. Une protéinase préférée de cette invention contient la séquence d'acides aminés ayant le numéro d'identification de séquence 2 (SEQ ID NO:2).
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5990797P | 1997-09-24 | 1997-09-24 | |
| US60/059,907 | 1997-09-24 | ||
| PCT/US1998/020186 WO1999015675A1 (fr) | 1997-09-24 | 1998-09-24 | PROTEINASE DE DEGRADATION DE LA PROTEINE DE COMPLEMENT HUMAIN C3, TIREE DU $i(STREPTOCOCCUS PNEUMONIAE) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2305016A1 true CA2305016A1 (fr) | 1999-04-01 |
Family
ID=22026061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002305016A Abandoned CA2305016A1 (fr) | 1997-09-24 | 1998-09-24 | Proteinase de degradation de la proteine de complement humain c3, tiree du streptococcus pneumoniae |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1017828A1 (fr) |
| JP (1) | JP2001517449A (fr) |
| KR (1) | KR20010024299A (fr) |
| CN (1) | CN1291233A (fr) |
| AU (1) | AU9510598A (fr) |
| BR (1) | BR9812525A (fr) |
| CA (1) | CA2305016A1 (fr) |
| WO (1) | WO1999015675A1 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6245335B1 (en) | 1996-05-01 | 2001-06-12 | The Rockefeller University | Choline binding proteins for anti-pneumococcal vaccines |
| ATE348887T1 (de) | 1996-10-31 | 2007-01-15 | Human Genome Sciences Inc | Streptococcus pneumoniae antigene und impfstoffe |
| US6676943B1 (en) | 1997-04-24 | 2004-01-13 | Regents Of The University Of Minnesota | Human complement C3-degrading protein from Streptococcus pneumoniae |
| EP1783224A3 (fr) * | 1998-07-27 | 2007-08-15 | Sanofi Pasteur Limited | Protéines de Streptococcus pneumoniae et molécules d'acide nucléique |
| US6936252B2 (en) | 1998-07-27 | 2005-08-30 | Microbial Technics Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
| EP1115875A1 (fr) * | 1998-09-24 | 2001-07-18 | Regents Of The University Of Minnesota | Polypeptide de degradation du complement humain c3 de streptococcus pneumoniae |
| CA2355364C (fr) | 1998-12-21 | 2014-03-18 | Medimmune, Inc. | Proteines de streptococcus pneumoniae et fragments immunogenes pour vaccins |
| EP1950302B1 (fr) * | 1998-12-23 | 2012-12-05 | ID Biomedical Corporation of Quebec | Nouveaux antigènes de streptocoque |
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| AU2005209689B2 (en) * | 1998-12-23 | 2008-07-17 | Id Biomedical Corporation Of Quebec | Novel streptococcus antigens |
| PL205041B1 (pl) * | 1998-12-23 | 2010-03-31 | Id Biomedical Corp | Izolowany polinukleotyd, wektor zawierający izolowany polinukleotyd, komórka gospodarza transfekowana lub transformowana za pomocą tego wektora, sposób wytwarzania polipeptydu kodowanego przez izolowany polinukleotyd, izolowany polipeptyd, chimeryczny polipeptyd, kompozycja do szczepionek zawierająca polipeptyd oraz jej zastosowanie w leczeniu lub zapobieganiu zakażeniu osobnika paciorkowcem |
| WO2001098334A2 (fr) * | 2000-06-20 | 2001-12-27 | Shire Biochem Inc. | Antigenes de streptocoque |
| US7074415B2 (en) | 2000-06-20 | 2006-07-11 | Id Biomedical Corporation | Streptococcus antigens |
| GB0022742D0 (en) | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| BR0116756A (pt) * | 2000-12-28 | 2005-01-04 | Wyeth Corp | Proteìna protetora recombinante de streptococcus pneumoniae e uso da mesma |
| US7262024B2 (en) | 2001-12-20 | 2007-08-28 | Id Biomedical Corporation | Streptococcus antigens |
| KR101126423B1 (ko) * | 2005-10-21 | 2012-07-11 | 카탈리스트 바이오사이언시즈, 인코포레이티드 | 보체 활성화를 억제하는 변형된 프로테아제 |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| GB0607088D0 (en) | 2006-04-07 | 2006-05-17 | Glaxosmithkline Biolog Sa | Vaccine |
| JP5792920B2 (ja) | 2005-12-22 | 2015-10-14 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| EA200901578A1 (ru) | 2007-06-26 | 2010-08-30 | Глаксосмитклайн Байолоджикалс С.А. | Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae |
| KR20110009157A (ko) | 2008-04-16 | 2011-01-27 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 |
| GB201003920D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Method of treatment |
| GB201003924D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| KR20140033127A (ko) | 2011-05-17 | 2014-03-17 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 스트렙토코쿠스 뉴모니애에 대한 백신 |
| CN102731739B (zh) * | 2012-07-05 | 2013-11-06 | 富阳经略化工技术有限公司 | 用作润滑油粘度指数改进剂的星形聚合物及其制备方法和应用 |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| GB201711635D0 (en) | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE348887T1 (de) * | 1996-10-31 | 2007-01-15 | Human Genome Sciences Inc | Streptococcus pneumoniae antigene und impfstoffe |
| EP0977872A1 (fr) * | 1997-04-24 | 2000-02-09 | Regents Of The University Of Minnesota | PROTEINASE, ISSUE DE $i(STREPTOCOCCUS PNEUMONIAE) DEGRADANT LA PROTEINE C3 HUMAINE DU COMPLEMENT |
-
1998
- 1998-09-24 EP EP98948557A patent/EP1017828A1/fr not_active Withdrawn
- 1998-09-24 KR KR1020007003198A patent/KR20010024299A/ko not_active Withdrawn
- 1998-09-24 BR BR9812525-7A patent/BR9812525A/pt not_active Application Discontinuation
- 1998-09-24 AU AU95105/98A patent/AU9510598A/en not_active Abandoned
- 1998-09-24 JP JP2000512965A patent/JP2001517449A/ja active Pending
- 1998-09-24 CN CN98809460A patent/CN1291233A/zh active Pending
- 1998-09-24 WO PCT/US1998/020186 patent/WO1999015675A1/fr not_active Ceased
- 1998-09-24 CA CA002305016A patent/CA2305016A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001517449A (ja) | 2001-10-09 |
| BR9812525A (pt) | 2000-07-25 |
| WO1999015675A1 (fr) | 1999-04-01 |
| KR20010024299A (ko) | 2001-03-26 |
| AU9510598A (en) | 1999-04-12 |
| EP1017828A1 (fr) | 2000-07-12 |
| CN1291233A (zh) | 2001-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |