CA2305433A1 - Child-proof pack for pressure-sensitive products which also have a comparatively large surface, such as transdermal therapy systems (tts) - Google Patents

Child-proof pack for pressure-sensitive products which also have a comparatively large surface, such as transdermal therapy systems (tts) Download PDF

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Publication number
CA2305433A1
CA2305433A1 CA002305433A CA2305433A CA2305433A1 CA 2305433 A1 CA2305433 A1 CA 2305433A1 CA 002305433 A CA002305433 A CA 002305433A CA 2305433 A CA2305433 A CA 2305433A CA 2305433 A1 CA2305433 A1 CA 2305433A1
Authority
CA
Canada
Prior art keywords
package
pack
sheet
aid
edge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002305433A
Other languages
French (fr)
Inventor
Frank Becher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2305433A1 publication Critical patent/CA2305433A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/52Details
    • B65D75/58Opening or contents-removing devices added or incorporated during package manufacture
    • B65D75/5827Tear-lines provided in a wall portion
    • B65D75/585Tear-lines provided in a wall portion the tear-lines being broken by deformation or bending
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/36Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
    • B65D75/366Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed and forming one compartment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2575/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D2575/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by association or interconnecting two or more sheets or blanks
    • B65D2575/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D2575/36One sheet or blank being recessed and the other formed or relatively stiff flat sheet material, e.g. blister packages
    • B65D2575/361Details
    • B65D2575/362Details with special means for gaining access to the contents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/305Skin packages

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Packages (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention relates to a child-safe pack (10) for pressure-sensitive therapeutic products which also have a comparatively large surface (1), such as transdermal therapy systems (TTS). Said pack is configured as a blister-peel pack with a comparatively dimensionally stable, transparent or translucent support film (2) and a peelable, comparatively highly flexible and extremely tear-resistant cover film (3), at least one area (4) for accommodating the product (1) being formed. The pack can be sealed with a sealing medium on adherends around a peripheral edge (5). The invention is characterised in that an aid to breaking the pack open (6) is provided in the form of a weakened section (9) in the film (2). Said weakened section is located along a join line (x-x) in the pack (10) and is weakened by indentation, perforation or embrittlement. The section can be broken open by bending to expose a breaking edge (20) which is used to hold and peel away the cover film (3) over the support film (2). The inventive pack is also characterised in that the stiffness of the sealed-together films (2,3) in relation to the weakened section (9) is measured in such a way that the strength required to bend the aid to breaking the pack open (6) is too great for a child's fingers but is appropriate for an adult.

Description

Childproof package for comparatively large-surfaced and pressure-sensitive products such as transdermal therapeutic systems (TTS) The invention relates to a childproof package for comparatively large-surfaced and pressure-sensitive products such as transdermal therapeutic systems (TTS) etc.
It is known that to ensure the important "childproof"
quality e.g. of a package in the form of a bag, it is necessary to use highly tear-resistant webs of packaging material for the production of said package. These webs of packaging material must also have barrier characteristics to prevent the permeability of the packaging material for the used active substance and its volatilization products as well as steam and air moisture. In addition, a strong, uninterrupted and tightly sealed seam extending entirely about the periphery of the package must form an impermeable sealed border of the package to maintain the necessary barrier function. Furthermore, specially chosen sealing materials or combinations of sealing materials such as e.g.
TE-peel, peel lacquers etc. must be employed to achieve the desired peel characteristics at tightly sealed seams.
Childproof packages for solid pharmaceuticals already exist on the market. The packages in guestion, such as blister strips, blister cards and blister bands, are sealed with childproof materials and can be opened without the aid of tools. The contents of these packages are pressure-insensitive products such as tablets, pills, capsules, etc.
which are removed by exerting force and pressing them out of the package through a cover sheet which mostly consists of aluminum foil. The force necessary is such that it cannot be exerted by children's hands.
A number of states are currently considering or have already enacted binding regulations concerning the introduction of childproof packages for a series of pharmaceutical products. This particularly concerns pharmaceuticals which present a high risk especially for children because the improper use or intake of their formulation has a toxic effect. On the other hand, medicaments which are flexible and pressure-sensitive due to their special structure and application form cannot be pressed through a package as described above. Yet many patients consider it disadvantageous and annoying if they have to use a tool such as a knife or a pair of scissors to remove a therapeutic product from a childproof package.
It is the object of the invention to provide an especially childproof package for comparatively large-surfaced and pressure-sensitive products such as transdermal therapeutic systems (TTS) etc. which can be opened without the aid of a tool and without exerting any pressure.
The invention achieves this object by means of a childproof package of the kind described in the introductory part of Claim 1 and having the qualities named in the characterizing part.
The especial advantages of this invention are that it provides for a childproof package which can easily be opened without the aid of a tool and totally without exertion of pressure on the product and that the package in this form is ideally suited for the packaging of comparatively large-surfaced and pressure-sensitive therapeutic products such as transdermal therapeutic systems, with the stiffness of the sealed-together sheets in the vicinity of the weakening advantageously being such that children do not possess the manual strength necessary for flexing the rupturing aid, but adults do.
One embodiment provides that after the carrier sheet is ruptured, the broken-off piece of said sheet forms a gripping aid for peeling the cover sheet from the edge of the carrier sheet, which considerably facilitates the exposure and removal of the product.
Advantageous embodiments of the childproof package are provided for according to the dependant claims.
Further details, characteristics and advantages of the invention are given in the following explanation of the example schematically presented in the drawings.
Fig. 1 shows a cross-sectional view of a childproof package with a rupturing aid in the carrier sheet;
Fig. 2 shows a top plan view of the childproof package according to Fig. 1;
Fig. 3 shows a sectional view of the childproof package after the rupturing aid is broken open and during the peeling of the cover sheet from the product with the help of the broken-open gripping aid.
Fig. 4 shows a sectional view of an embodiment of the childproof package with a receiving tray, an adjacent gripping depression on the carrier sheet, and an adhesive product.
Fig. 5 shows a sectional view of a further embodiment of the package with a product adhering to the carrier sheet and an adjacent gripping aid.
In Fig. 1, the childproof package 10 for comparatively large-surfaced and pressure-sensitive therapeutic products 1 such as transdermal therapeutic systems (TTS) etc.
according to the invention is embodied as a blister-peel-- package with a comparatively dimensionally stable, transparent or translucent carrier sheet 2 and a peelable, comparatively highly flexible and extremely tear-resistant cover sheet 3 and with at least one receiving space 4 for the product 1. The package can be sealed with sealing material at the adhesive surfaces of the edge 5 extending entirely about the periphery of the package. It has a rupturing aid 6 in the vicinity of the edge 5 in the form of a weakening of the sheet 2, for example by scoring, perforating or embrittlement, etc., along a line x-x of the package 10. This rupturing aid can be broken by flexing the weakened sheet 2 and thus exposes a broken edge 20 by means of which the carrier sheet 3 can be gripped and peeled from the carrier sheet 2. (Fig. 3) In this embodiment, the necessary childproof guality of the package 10 is achieved according to the invention by providing that the stiffness of the sheets 2 and 3, which are sealed together at the edge 5 of the package, in relation to the weakening 9 in the vicinity of the rupturing aid 6 along the connection line x-x is such that children do not possess the manual strength necessary for flexing the rupturing aid 6, but adults do.
To illustrate the arrangement and embodiment of the various elements of the childproof package 10, Fig. 2 contains a top plan view of said package. This shows the position of the product 1, e.g. a round TTS, in the center of the package 10 within a receiving space 4 which is formed out of the cover sheet 3, as well as the sealed peripheral areas 5. In the vicinity of the peripheral areas 5 beyond the thin broken line, the carrier and cover sheets 2 and 3 are sealed with sealing material.
Fig. 3 shows a package 10 according to the invention after the rupturing aid 6 in the carrier sheet 2 is broken, resulting in a gripping aid 14 with the broken edge 20 connected to the cover sheet 3. Said gripping aid 14 can be bent back and used to peel off the cover sheet 3 to expose the product 1. This presents an uncomplicated possibility of opening the package 10 without exerting pressure on the product 1 contained within.
Fig. 4 shows an embodiment of the package 10 in which the carrier sheet 2 has at least one receiving tray 8 for a therapeutic product 1. To enable an easy grasping of the product 1 after the package is opened,. the package can have an additional gripping depression 11 at the edge of the receiving tray 8 which facilitates taking hold of the product 1. This is especially expedient if, as in the example in Fig. 4, the product 1 adheres to the carrier sheet 2 by means of an adhesive layer 19. To guarantee the unproblematic release of the product 1 with its adhesive layer 19 from the carrier sheet 2 after said carrier sheet 2 is broken at the rupturing aid 16, the carrier sheet 2 has an additional weakening 16' which results in a broken edge 21 upon flexing. The weakening 16 of the carrier sheet 2 can preferably be embodied as a nominal breaking line and preferably be placed close to the gripping depression 11.
Fig. 5 shows another embodiment of the package 10 in which an adhesive product 1 is applied to a level, comparatively stiff carrier sheet 2 and is then covered and enveloped, with almost complete form closure, with an especially flexible cover sheet 3, the package being sealed at the periphery. As an additional practical measure, a rigid gripping aid 17 in the form of a tab can be arranged extending from the edge of the patch 1 adhering to the carrier sheet to facilitate the release of said pressure-sensitive adhesive patch 1.

Claims (5)

6
1. Childproof package (10) for comparatively large-surfaced and pressure-sensitive therapeutic products (1) such as transdermal therapeutic systems (TTS), as a blister-peel package with a comparatively dimensionally stable, transparent or translucent carrier sheet (2) and a peelable, comparatively highly flexible and extremely tear-resistant cover sheet (3), being seelable, under formation of at least one receiving space (4) for the product (1), with sealing material at the adhesive surfaces of the edge (5) extending entirely about the periphery of the package, said package being characterized in that - it has a rupturing aid in the form of a weakening line (6), for example by scoring, perforating or embrittlement of the dimensionally stable carrier sheet (2) along a line (x-x) an the underside thereof, - the weakening line (6) can be undone by bending backwards and tearing open of the sheet (2) thus exposing a broken edge (20) and forming on the cover sheet (3) a gripping aid (14), which can be bent backwards, with the broken edge (20), and - the strength and stiffness of the sheets (2, 3) sealed together is chosen such that childrens' hands are unable to exert the force from the fingers which is necessary for bending backwards and tearing open the carrier sheet (2) at the rupturing aid (6) until the weakening line (x-x) breaks, but adults are easily capable of doing so.
2. Childproof package according to Claim 1, characterized in that after the carrier sheet (2) a.s ruptured, the broken-off piece of said sheet (14) forms a gripping aid for peeling the cover sheet (3) from the edge (5) of the carrier sheet (2).
3. Childproof package according to Claim 1 or 2, characterized in that the product (1) is applied to the level, comparatively stiff carrier sheet (2) and is covered with an especially flexible cover sheet (3), the package being sealed with form closure at the periphery.
4. Childproof package according to one or more of the Claims 1 to 3, characterized in that the cover sheet (3) is formed as a release-liner for an adhesive product (1) and in that said package has a gripping aid (17) projecting from the edge of the product (1) to facilitate the peeling of said product (1) from the carrier sheet.
5. Childproof package according to one or more of the Claims 1 to 4, characterized in that a rigid gripping aid (17) in the form of a tab is arranged projecting from the edge of an adhesive patch (1) to facilitate the release of said patch (1).
CA002305433A 1997-10-01 1998-09-18 Child-proof pack for pressure-sensitive products which also have a comparatively large surface, such as transdermal therapy systems (tts) Abandoned CA2305433A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19743485.1 1997-10-01
DE19743485A DE19743485A1 (en) 1997-10-01 1997-10-01 Childproof pack for comparatively large and pressure-sensitive therapeutic products such as a transdermal therapeutic system
PCT/EP1998/005954 WO1999021777A1 (en) 1997-10-01 1998-09-18 Child-proof pack for pressure-sensitive products which also have a comparatively large surface, such as transdermal therapy systems (tts)

Publications (1)

Publication Number Publication Date
CA2305433A1 true CA2305433A1 (en) 1999-05-06

Family

ID=7844346

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002305433A Abandoned CA2305433A1 (en) 1997-10-01 1998-09-18 Child-proof pack for pressure-sensitive products which also have a comparatively large surface, such as transdermal therapy systems (tts)

Country Status (15)

Country Link
EP (1) EP1019300A1 (en)
JP (1) JP2001520969A (en)
KR (1) KR20010030887A (en)
AU (1) AU1023899A (en)
CA (1) CA2305433A1 (en)
CZ (1) CZ20001120A3 (en)
DE (1) DE19743485A1 (en)
HU (1) HUP0003739A3 (en)
IL (1) IL135304A0 (en)
PL (1) PL339577A1 (en)
SK (1) SK4652000A3 (en)
TR (1) TR200000780T2 (en)
TW (1) TW404923B (en)
WO (1) WO1999021777A1 (en)
ZA (1) ZA988905B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004047447B4 (en) * 2004-09-30 2008-01-03 Lts Lohmann Therapie-Systeme Ag Peelable, child resistant packaging for flat flexible objects, use of these packages and methods of packaging flat, flexible objects
US9216850B2 (en) 2006-09-26 2015-12-22 Intercontinental Great Brands Llc Rupturable substrate
PL2069215T3 (en) 2006-09-26 2012-10-31 Intercontinental Great Brands Llc Rupturable blister package
JP5244553B2 (en) * 2008-11-17 2013-07-24 日東電工株式会社 Blister packaging
DE102010033982A1 (en) * 2010-08-06 2012-02-09 Hochschule für Technik und Wirtschaft Berlin. Packaging with a carrier element which can be separated from the packaging for a medicament and outer packaging

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3371848A (en) * 1966-10-24 1968-03-05 Anderson Bros Mfg Co Reclosable package
BE793150A (en) * 1971-12-24 1973-06-21 Kalle Ag Resealable packaging box
US3921805A (en) * 1972-10-10 1975-11-25 Newton L Compere Rupturable blister pill package with safety backing
US3948394A (en) * 1973-09-28 1976-04-06 Hellstrom H Richard Child-proofed quick-opening package
US3872970A (en) * 1974-01-11 1975-03-25 Lilly Co Eli Child-resistant blister package
US4106621A (en) * 1976-07-26 1978-08-15 Sorenson Research Co., Inc. Combination needle cover and venipuncture device tray and method of using same
DE2751078C3 (en) * 1977-11-15 1981-10-22 Ludwig Dipl.-Ing. Dr. 8081 Eching Blasy Container for flowable materials
US4243144A (en) * 1979-04-09 1981-01-06 Sterling Drug Inc. Bend and peel blister strip package
DE8108521U1 (en) * 1981-03-24 1981-07-23 Aluminium Féron GmbH & Co, 5160 Düren Childproof packaging for tablets, dragees, capsules and the like
GB2235912A (en) * 1989-08-29 1991-03-20 Grace W R & Co Easy-open package and method of forming the same
DE4429663C2 (en) * 1994-08-20 1997-09-11 Lohmann Therapie Syst Lts Transdermal therapeutic system with hydrolysis protection

Also Published As

Publication number Publication date
IL135304A0 (en) 2001-05-20
HUP0003739A2 (en) 2001-03-28
ZA988905B (en) 1999-04-12
TW404923B (en) 2000-09-11
CZ20001120A3 (en) 2001-12-12
DE19743485A1 (en) 1999-04-15
WO1999021777A1 (en) 1999-05-06
KR20010030887A (en) 2001-04-16
WO1999021777A9 (en) 1999-06-24
EP1019300A1 (en) 2000-07-19
JP2001520969A (en) 2001-11-06
PL339577A1 (en) 2000-12-18
HUP0003739A3 (en) 2002-03-28
SK4652000A3 (en) 2000-08-14
TR200000780T2 (en) 2000-08-21
AU1023899A (en) 1999-05-17

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20030918