CA2312477A1 - Canaux calciques potentiel-dependants de type t et leurs methodes d'utilisation - Google Patents
Canaux calciques potentiel-dependants de type t et leurs methodes d'utilisation Download PDFInfo
- Publication number
- CA2312477A1 CA2312477A1 CA002312477A CA2312477A CA2312477A1 CA 2312477 A1 CA2312477 A1 CA 2312477A1 CA 002312477 A CA002312477 A CA 002312477A CA 2312477 A CA2312477 A CA 2312477A CA 2312477 A1 CA2312477 A1 CA 2312477A1
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- Prior art keywords
- leu
- ser
- arg
- ctg
- pro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 238000000338 in vitro Methods 0.000 claims description 8
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention concerne un acide nucléique isolé ou sensiblement purifié codant une protéine comprenant au moins un domaine d'un canal calcique de type T, ainsi que des cellules et des lignées cellulaires exprimant ces acides nucléiques. La présente invention concerne également un canal calcique de type T isolé ou sensiblement purifié et une molécule anticorps isolée ou sensiblement purifiée reconnaissant un épitope sur une protéine de canal calcique de type T.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98580997A | 1997-12-05 | 1997-12-05 | |
| US08/985,809 | 1997-12-05 | ||
| PCT/US1998/023161 WO1999029847A1 (fr) | 1997-12-05 | 1998-10-30 | Canaux calciques potentiel-dependants de type t et leurs methodes d'utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2312477A1 true CA2312477A1 (fr) | 1999-06-17 |
Family
ID=25531814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002312477A Abandoned CA2312477A1 (fr) | 1997-12-05 | 1998-10-30 | Canaux calciques potentiel-dependants de type t et leurs methodes d'utilisation |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP1036170A1 (fr) |
| CA (1) | CA2312477A1 (fr) |
| WO (1) | WO1999029847A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7297504B1 (en) | 1997-02-28 | 2007-11-20 | Neuromed Pharmaceuticals Ltd. | Methods for identifying agonists and antagonists of human T-type calcium channels |
| US20020009772A1 (en) * | 1997-02-28 | 2002-01-24 | Terry P. Snutch | Novel human calcium channels and related probes, cell lines and mehtods |
| US6309858B1 (en) | 1998-09-29 | 2001-10-30 | Syntex (U.S.A.) Llc | T-type calcium channel variants; compositions thereof; and uses |
| AU4989500A (en) * | 1999-05-13 | 2000-12-05 | Johns Hopkins University, The | Human brain t calcium channel alpha-subunit splice variants |
| JP2003504020A (ja) * | 1999-07-02 | 2003-02-04 | ニューロメド テクノロジーズ， インコーポレイテッド | 新規な哺乳動物カルシウムチャネルならびに関連するプローブ、細胞株および方法 |
| US6358706B1 (en) * | 1999-10-26 | 2002-03-19 | Ortho-Mcneil Pharmaceutical, Inc. | DNA encoding human alpha1G-C T-Type calcium channel |
| GB0003069D0 (en) * | 2000-02-11 | 2000-03-29 | Cambridge Drug Discovery Ltd | Improved assay |
| WO2002101035A1 (fr) * | 2001-05-10 | 2002-12-19 | Mochida Pharmaceutical Co., Ltd. | Proteine du canal cation dependant du potentiel |
| AU2011203315B8 (en) * | 2004-02-11 | 2012-02-16 | University Of Virginia Patent Foundation | Inhibiting CAV3 isoforms and the delta25B splice varients for the diagnosis and treatment of cancer |
| JP2008501633A (ja) * | 2004-02-11 | 2008-01-24 | ユニバーシティ オブ ヴァージニア パテント ファウンデーション | 癌の診断及び治療のためのＣａｖ３アイソフォーム及びそのδ２５スプライスバリアントの阻害 |
| CA2566041A1 (fr) * | 2004-05-10 | 2005-11-17 | Neuromed Pharmaceuticals Ltd. | Compositions a base de variants d'epissage des canaux calciques de type t, et methodes associees |
| EP2542155B1 (fr) | 2010-03-01 | 2015-11-04 | TAU Therapeutics LLC | Procédé d'imagerie d'une maladie |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2147184T3 (es) * | 1991-08-15 | 2000-09-01 | Merck & Co Inc | Composiciones de canales calcicos humanos y procedimientos. |
| ES2151560T3 (es) * | 1993-07-30 | 2001-01-01 | Elan Pharm Inc | Adn codificador de una subunidad alfa-1e de canales de calcio humanos. |
-
1998
- 1998-10-30 CA CA002312477A patent/CA2312477A1/fr not_active Abandoned
- 1998-10-30 EP EP98956416A patent/EP1036170A1/fr not_active Withdrawn
- 1998-10-30 WO PCT/US1998/023161 patent/WO1999029847A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1036170A1 (fr) | 2000-09-20 |
| WO1999029847A1 (fr) | 1999-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |