CA2316545A1 - Nouvel acide nucleique et nouveau polypeptide - Google Patents
Nouvel acide nucleique et nouveau polypeptide Download PDFInfo
- Publication number
- CA2316545A1 CA2316545A1 CA002316545A CA2316545A CA2316545A1 CA 2316545 A1 CA2316545 A1 CA 2316545A1 CA 002316545 A CA002316545 A CA 002316545A CA 2316545 A CA2316545 A CA 2316545A CA 2316545 A1 CA2316545 A1 CA 2316545A1
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- ntr
- polypeptide
- mammalian
- human
- nucleic acid
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- LNYOXPDEIZJDEI-NHCYSSNCSA-N Val-Asn-Leu Chemical compound CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C(C)C)N LNYOXPDEIZJDEI-NHCYSSNCSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La présente invention porte sur des séquences d'acide nucléique codant de nouveaux polypeptides récepteurs mammaliens appelés NTR-5. Cette invention porte également sur des systèmes de dosage pouvant être utilisés pour détecter et/ou mesurer des ligands qui fixent le produit génique mammalien NTR-5, ainsi que sur des méthodes diagnostiques et thérapeutiques basées sur l'interaction entre NTR-5 mammalien et des agents qui déclenchent la transduction du signal par fixation sur NTR-5. Selon une réalisation spécifique, NTR-5 mammalien peut être un NTR-5 humain ou de souris.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6892597P | 1997-12-29 | 1997-12-29 | |
| US60/068,925 | 1997-12-29 | ||
| PCT/US1998/027688 WO1999033967A2 (fr) | 1997-12-29 | 1998-12-28 | Nouvel acide nucleique et nouveau polypeptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2316545A1 true CA2316545A1 (fr) | 1999-07-08 |
Family
ID=22085585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002316545A Abandoned CA2316545A1 (fr) | 1997-12-29 | 1998-12-28 | Nouvel acide nucleique et nouveau polypeptide |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1044267A2 (fr) |
| JP (1) | JP2002508934A (fr) |
| AU (1) | AU748167B2 (fr) |
| CA (1) | CA2316545A1 (fr) |
| IL (1) | IL136988A0 (fr) |
| WO (1) | WO1999033967A2 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1012179A2 (fr) | 1997-09-12 | 2000-06-28 | Apotech R&D S.A. | Recepteurs "trail" riches en cysteine |
| JP2002528046A (ja) * | 1998-01-27 | 2002-09-03 | ミレニアム・フアーマシユーチカルズ・インコーポレーテツド | 新規レセプタースーパーファミリー分子およびそれについての用途 |
| AU2574200A (en) * | 1999-02-19 | 2000-09-04 | Toshio Kitamura | Novel tnf receptor-like proteins |
| JP2003505045A (ja) * | 1999-07-16 | 2003-02-12 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ヒト腫瘍壊死因子レセプターｔｒ１３およびｔｒ１４ |
| US6951738B2 (en) | 1999-07-16 | 2005-10-04 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors TR13 and TR14 |
| DE60235418D1 (de) | 2001-04-03 | 2010-04-01 | Nestle Sa | Osteoprotegerin in Milch |
| EP1789070B1 (fr) | 2004-08-03 | 2012-10-24 | Biogen Idec MA Inc. | Influence du taj sur les fonctions neuronales |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965388A (en) * | 1996-07-09 | 1999-10-12 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
| WO1997041895A2 (fr) * | 1996-05-08 | 1997-11-13 | F. Hoffmann-La Roche Ag | TRAITEMENT DE L'ASTHME PAR TNFR-Ig |
| DE69839582D1 (de) * | 1997-02-27 | 2008-07-17 | Ono Pharmaceutical Co | Neues polypeptid, dafür kodierende dna und deren verwendungen |
| AU9376498A (en) * | 1997-09-05 | 1999-03-22 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
| EP1012179A2 (fr) * | 1997-09-12 | 2000-06-28 | Apotech R&D S.A. | Recepteurs "trail" riches en cysteine |
-
1998
- 1998-12-28 CA CA002316545A patent/CA2316545A1/fr not_active Abandoned
- 1998-12-28 IL IL13698898A patent/IL136988A0/xx unknown
- 1998-12-28 JP JP2000526625A patent/JP2002508934A/ja active Pending
- 1998-12-28 WO PCT/US1998/027688 patent/WO1999033967A2/fr not_active Ceased
- 1998-12-28 AU AU22079/99A patent/AU748167B2/en not_active Ceased
- 1998-12-28 EP EP98966103A patent/EP1044267A2/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999033967A3 (fr) | 1999-09-10 |
| IL136988A0 (en) | 2001-06-14 |
| AU748167B2 (en) | 2002-05-30 |
| AU2207999A (en) | 1999-07-19 |
| JP2002508934A (ja) | 2002-03-26 |
| WO1999033967A2 (fr) | 1999-07-08 |
| EP1044267A2 (fr) | 2000-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20041229 |