CA2335293A1 - Inhibitors of transcription factor nf-.kappa.b - Google Patents

Inhibitors of transcription factor nf-.kappa.b Download PDF

Info

Publication number: CA2335293A1
Authority: CA; Canada
Prior art keywords: group; disease; benzalindanone; compound; 6alkyl
Prior art date: 1998-06-19
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002335293A

Other languages

English (en)

French (fr)

Inventor

Marie C. Chabot-Fletcher

James F. Callahan

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-19

Filing date

1999-06-18

Publication date

1999-12-23

1999-06-18 Application filed by Individual filed Critical Individual

1999-12-23 Publication of CA2335293A1 publication Critical patent/CA2335293A1/en

Status Abandoned legal-status Critical Current

Links

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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
- A—HUMAN NECESSITIES
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Dermatology (AREA)
Virology (AREA)
Biomedical Technology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Communicable Diseases (AREA)
Toxicology (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Hospice & Palliative Care (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
AIDS & HIV (AREA)

CA002335293A 1998-06-19 1999-06-18 Inhibitors of transcription factor nf-.kappa.b Abandoned CA2335293A1 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US9001698P	1998-06-19	1998-06-19
US60/090,016		1998-06-19
PCT/US1999/013897 WO1999065495A1 (en)	1998-06-19	1999-06-18	INHIBITORS OF TRANSCRIPTION FACTOR NF-λB

Publications (1)

Publication Number	Publication Date
CA2335293A1 true CA2335293A1 (en)	1999-12-23

Family

ID=22220761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002335293A Abandoned CA2335293A1 (en)	1998-06-19	1999-06-18	Inhibitors of transcription factor nf-.kappa.b

Country Status (17)

Country	Link
EP (1)	EP1085872A4 (cs)
JP (1)	JP2002518333A (cs)
KR (1)	KR20010052990A (cs)
CN (1)	CN1306428A (cs)
AR (1)	AR019871A1 (cs)
AU (1)	AU4699699A (cs)
BR (1)	BR9911151A (cs)
CA (1)	CA2335293A1 (cs)
CO (1)	CO5080752A1 (cs)
CZ (1)	CZ20004760A3 (cs)
HU (1)	HUP0102492A2 (cs)
IL (1)	IL140324A0 (cs)
NO (1)	NO20006452L (cs)
PL (1)	PL345577A1 (cs)
TR (1)	TR200003779T2 (cs)
WO (1)	WO1999065495A1 (cs)
ZA (1)	ZA200007448B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1999058674A2 (en)	1998-05-14	1999-11-18	Immunex Corporation	Method of inhibiting osteoclast activity
ATE497001T1 (de)	1996-12-23	2011-02-15	Immunex Corp	Rezeptor aktivator von nf-kappa b, rezeptor is mitglied der tnf rezeptor superfamilie
US6316408B1 (en)	1997-04-16	2001-11-13	Amgen Inc.	Methods of use for osetoprotegerin binding protein receptors
AU2968701A (en) *	2000-01-24	2001-07-31	Genzyme Corporation	Jak/stat pathway inhibitors and the uses thereof
US20060148732A1 (en) *	2000-11-17	2006-07-06	Gutterman Jordan U	Inhibition of NF-kappaB by triterpene compositions
TR201809678T4 (tr)	2001-06-26	2018-07-23	Amgen Fremont Inc	Opgl ye karşi antikorlar.
US7425580B2 (en)	2004-05-19	2008-09-16	Wyeth	(Diaryl-methyl)-malononitriles and their use as estrogen receptor ligands
WO2007097981A2 (en)	2006-02-16	2007-08-30	Millennium Pharmaceuticals, Inc.	Alpha carbolines and uses thereof
EP2366699B1 (en)	2008-10-02	2013-08-07	Asahi Kasei Pharma Corporation	8-substituted isoquinoline derivative and use thereof
WO2010108058A2 (en)	2009-03-20	2010-09-23	University Of Pittsburgh-Of The Commonwealth System Of Higher Education	Small molecule inhibitors of dusp6 and uses therefor
US9186365B2 (en) *	2009-07-31	2015-11-17	The United States Of America, As Represented By The Secretary, Department Of Health And Human Services	Antiangiogenic small molecules and methods of use
WO2012109527A2 (en)	2011-02-10	2012-08-16	University Of Pittsburgh - Of The Commonwealth System Of Higher Education	Class of hdac inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury
US9670236B2 (en)	2012-10-31	2017-06-06	University of Pittsburgh—of the Commonwealth System of Higher Education	Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury

1998
- 1998-06-18 HU HU0102492A patent/HUP0102492A2/hu unknown
1999
- 1999-06-17 CO CO99037918A patent/CO5080752A1/es unknown
- 1999-06-18 JP JP2000554375A patent/JP2002518333A/ja not_active Withdrawn
- 1999-06-18 AR ARP990102952A patent/AR019871A1/es unknown
- 1999-06-18 AU AU46996/99A patent/AU4699699A/en not_active Abandoned
- 1999-06-18 CN CN99807572A patent/CN1306428A/zh active Pending
- 1999-06-18 PL PL99345577A patent/PL345577A1/xx not_active Application Discontinuation
- 1999-06-18 BR BR9911151-9A patent/BR9911151A/pt not_active Application Discontinuation
- 1999-06-18 CZ CZ20004760A patent/CZ20004760A3/cs unknown
- 1999-06-18 WO PCT/US1999/013897 patent/WO1999065495A1/en not_active Ceased
- 1999-06-18 TR TR2000/03779T patent/TR200003779T2/xx unknown
- 1999-06-18 EP EP99930459A patent/EP1085872A4/en not_active Withdrawn
- 1999-06-18 IL IL14032499A patent/IL140324A0/xx unknown
- 1999-06-18 KR KR1020007014385A patent/KR20010052990A/ko not_active Withdrawn
- 1999-06-18 CA CA002335293A patent/CA2335293A1/en not_active Abandoned
2000
- 2000-12-13 ZA ZA200007448A patent/ZA200007448B/en unknown
- 2000-12-18 NO NO20006452A patent/NO20006452L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
PL345577A1 (en)	2001-12-17
TR200003779T2 (tr)	2001-06-21
IL140324A0 (en)	2002-02-10
CN1306428A (zh)	2001-08-01
AU4699699A (en)	2000-01-05
ZA200007448B (en)	2001-12-12
NO20006452D0 (no)	2000-12-18
EP1085872A1 (en)	2001-03-28
KR20010052990A (ko)	2001-06-25
CZ20004760A3 (cs)	2001-08-15
BR9911151A (pt)	2001-03-06
JP2002518333A (ja)	2002-06-25
CO5080752A1 (es)	2001-09-25
AR019871A1 (es)	2002-03-20
EP1085872A4 (en)	2003-04-16
HUP0102492A2 (hu)	2001-11-28
NO20006452L (no)	2001-02-16
WO1999065495A1 (en)	1999-12-23

Legal Events

Date	Code	Title	Description
2003-06-18	FZDE	Discontinued

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US6492425B1 (en)	2002-12-10	Inhibitors of transcription factor-NF-κB
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AU4699699A (en)	2000-01-05	Inhibitors of transcription factor NF-KappaB
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MXPA00012498A (en)	2001-11-21	INHIBITORS OF TRANSCRIPTION FACTOR NF-&kgr;B
US20040006118A1 (en)	2004-01-08	Nf-kb inhibitors