ZA200007448B - Inhibitors of transcription factor NF-kB. - Google Patents

Inhibitors of transcription factor NF-kB. Download PDF

Info

Publication number: ZA200007448B
Authority: ZA; South Africa
Prior art keywords: disease; group; compound; benzalindanone; pharmaceutical composition
Prior art date: 1998-06-19

Application number

ZA200007448A

Other languages

English (en)

Inventor

Callahan James Francis

Marie C Chabot-Fletcher

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-19

Filing date

2000-12-13

Publication date

2001-12-12

2000-12-13 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2001-12-12 Publication of ZA200007448B publication Critical patent/ZA200007448B/en

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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Immunology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Virology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Tropical Medicine & Parasitology (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Hospice & Palliative Care (AREA)
Toxicology (AREA)
Vascular Medicine (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
AIDS & HIV (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
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ZA200007448A 1998-06-19 2000-12-13 Inhibitors of transcription factor NF-kB. ZA200007448B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US9001698P	1998-06-19	1998-06-19

Publications (1)

Publication Number	Publication Date
ZA200007448B true ZA200007448B (en)	2001-12-12

Family

ID=22220761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200007448A ZA200007448B (en)	1998-06-19	2000-12-13	Inhibitors of transcription factor NF-kB.

Country Status (17)

Country	Link
EP (1)	EP1085872A4 (cs)
JP (1)	JP2002518333A (cs)
KR (1)	KR20010052990A (cs)
CN (1)	CN1306428A (cs)
AR (1)	AR019871A1 (cs)
AU (1)	AU4699699A (cs)
BR (1)	BR9911151A (cs)
CA (1)	CA2335293A1 (cs)
CO (1)	CO5080752A1 (cs)
CZ (1)	CZ20004760A3 (cs)
HU (1)	HUP0102492A2 (cs)
IL (1)	IL140324A0 (cs)
NO (1)	NO20006452L (cs)
PL (1)	PL345577A1 (cs)
TR (1)	TR200003779T2 (cs)
WO (1)	WO1999065495A1 (cs)
ZA (1)	ZA200007448B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT951551E (pt)	1996-12-23	2008-10-28	Immunex Corp	Ligando para receptor activador de nf-kb, ligando membro da superfamília de tnf
US6316408B1 (en)	1997-04-16	2001-11-13	Amgen Inc.	Methods of use for osetoprotegerin binding protein receptors
EP1076699B1 (en)	1998-05-14	2008-10-29	Immunex Corporation	Method of inhibiting osteoclast activity
ATE369844T1 (de) *	2000-01-24	2007-09-15	Genzyme Corp	Inhibitoren des jak/stat-weges und deren verwendung zur behandlung von allgemeiner primärer osteoarthritis
US20060148732A1 (en) *	2000-11-17	2006-07-06	Gutterman Jordan U	Inhibition of NF-kappaB by triterpene compositions
CA2451955C (en)	2001-06-26	2015-09-29	Abgenix, Inc.	Antibodies to opgl
US7425580B2 (en)	2004-05-19	2008-09-16	Wyeth	(Diaryl-methyl)-malononitriles and their use as estrogen receptor ligands
EP1989203A2 (en)	2006-02-16	2008-11-12	Millennium Pharmaceuticals, Inc.	Alpha carbolines and uses thereof
PL2366699T3 (pl)	2008-10-02	2013-12-31	Asahi Kasei Pharma Corp	8-podstawiona pochodna izochinoliny i jej zastosowanie
WO2010108058A2 (en) *	2009-03-20	2010-09-23	University Of Pittsburgh-Of The Commonwealth System Of Higher Education	Small molecule inhibitors of dusp6 and uses therefor
CA2769038A1 (en) *	2009-07-31	2011-02-03	The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services	Antiangiogenic small molecules and methods of use
WO2012109527A2 (en)	2011-02-10	2012-08-16	University Of Pittsburgh - Of The Commonwealth System Of Higher Education	Class of hdac inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury
US9670236B2 (en)	2012-10-31	2017-06-06	University of Pittsburgh—of the Commonwealth System of Higher Education	Class of HDAC inhibitors expands the renal progenitor cells population and improves the rate of recovery from acute kidney injury

1998
- 1998-06-18 HU HU0102492A patent/HUP0102492A2/hu unknown
1999
- 1999-06-17 CO CO99037918A patent/CO5080752A1/es unknown
- 1999-06-18 KR KR1020007014385A patent/KR20010052990A/ko not_active Withdrawn
- 1999-06-18 IL IL14032499A patent/IL140324A0/xx unknown
- 1999-06-18 AR ARP990102952A patent/AR019871A1/es unknown
- 1999-06-18 CN CN99807572A patent/CN1306428A/zh active Pending
- 1999-06-18 BR BR9911151-9A patent/BR9911151A/pt not_active Application Discontinuation
- 1999-06-18 WO PCT/US1999/013897 patent/WO1999065495A1/en not_active Ceased
- 1999-06-18 TR TR2000/03779T patent/TR200003779T2/xx unknown
- 1999-06-18 AU AU46996/99A patent/AU4699699A/en not_active Abandoned
- 1999-06-18 PL PL99345577A patent/PL345577A1/xx not_active Application Discontinuation
- 1999-06-18 JP JP2000554375A patent/JP2002518333A/ja not_active Withdrawn
- 1999-06-18 CA CA002335293A patent/CA2335293A1/en not_active Abandoned
- 1999-06-18 CZ CZ20004760A patent/CZ20004760A3/cs unknown
- 1999-06-18 EP EP99930459A patent/EP1085872A4/en not_active Withdrawn
2000
- 2000-12-13 ZA ZA200007448A patent/ZA200007448B/en unknown
- 2000-12-18 NO NO20006452A patent/NO20006452L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP1085872A4 (en)	2003-04-16
HUP0102492A2 (hu)	2001-11-28
BR9911151A (pt)	2001-03-06
NO20006452L (no)	2001-02-16
TR200003779T2 (tr)	2001-06-21
IL140324A0 (en)	2002-02-10
EP1085872A1 (en)	2001-03-28
KR20010052990A (ko)	2001-06-25
WO1999065495A1 (en)	1999-12-23
AU4699699A (en)	2000-01-05
CO5080752A1 (es)	2001-09-25
PL345577A1 (en)	2001-12-17
JP2002518333A (ja)	2002-06-25
CZ20004760A3 (cs)	2001-08-15
CA2335293A1 (en)	1999-12-23
CN1306428A (zh)	2001-08-01
NO20006452D0 (no)	2000-12-18
AR019871A1 (es)	2002-03-20

Publication	Publication Date	Title
US6492425B1 (en)	2002-12-10	Inhibitors of transcription factor-NF-κB
US7166639B2 (en)	2007-01-23	NF-κB inhibitors
WO2002030353A2 (en)	2002-04-18	NF-λB INHIBITORS
US20060116419A1 (en)	2006-06-01	Nf-kb inhibitors
JP2010502618A (ja)	2010-01-28	セロトニン５−ｈｔ２ａ受容体のモジュレータとしてのベンゾフラン誘導体
AU4699699A (en)	2000-01-05	Inhibitors of transcription factor NF-KappaB
WO2009051909A1 (en)	2009-04-23	Compounds having activity in correcting mutant-cftr cellular processing and uses thereof
ITMI971864A1 (it)	1999-02-01	Derivati 1- (n-fenilaminoalchil) piperazinici sostituiti alla posizione 2 dell'anello fenilico
EP1328272A1 (en)	2003-07-23	Nf-kappa-b inhibitors
US7183311B2 (en)	2007-02-27	NF-κB inhibitors
US20060058371A1 (en)	2006-03-16	Nf-kb inhibitors
MXPA00012499A (en)	2001-11-21	INHIBITORS OF TRANSCRIPTION FACTOR NF-&kgr;B
US20040024047A1 (en)	2004-02-05	Nf-kb inhibitors
MXPA00012498A (en)	2001-11-21	INHIBITORS OF TRANSCRIPTION FACTOR NF-&kgr;B
US20040006118A1 (en)	2004-01-08	Nf-kb inhibitors
ES2360763T3 (es)	2011-06-08	Derivados de piridina para el tratamiento de desórdenes metabólicos relacionados con la resistencia a la insulina o hiperglucemia.