CA2340177A1 - Formulation pharmaceutique - Google Patents

Formulation pharmaceutique Download PDF

Info

Publication number
CA2340177A1
CA2340177A1 CA002340177A CA2340177A CA2340177A1 CA 2340177 A1 CA2340177 A1 CA 2340177A1 CA 002340177 A CA002340177 A CA 002340177A CA 2340177 A CA2340177 A CA 2340177A CA 2340177 A1 CA2340177 A1 CA 2340177A1
Authority
CA
Canada
Prior art keywords
microparticles
gel
gel according
spray
physiological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002340177A
Other languages
English (en)
Inventor
Nicola Kim Whitfield
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Healthcare UK Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2340177A1 publication Critical patent/CA2340177A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Un gel comprend des microparticules biodégradables contenant une matière formant paroi laquelle est relativement insoluble à un pH physiologique, dans laquelle la phase liquide du gel est aqueuse, tamponnée à un pH physiologique.
CA002340177A 1998-08-11 1999-08-02 Formulation pharmaceutique Abandoned CA2340177A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9817470.9A GB9817470D0 (en) 1998-08-11 1998-08-11 Pharmaceutical formulation
GB9817470.9 1998-08-11
PCT/GB1999/002527 WO2000009084A2 (fr) 1998-08-11 1999-08-02 Formulation pharmaceutique

Publications (1)

Publication Number Publication Date
CA2340177A1 true CA2340177A1 (fr) 2000-02-24

Family

ID=10837065

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002340177A Abandoned CA2340177A1 (fr) 1998-08-11 1999-08-02 Formulation pharmaceutique

Country Status (6)

Country Link
EP (1) EP1105095A2 (fr)
JP (1) JP2002522467A (fr)
AU (1) AU5182099A (fr)
CA (1) CA2340177A1 (fr)
GB (1) GB9817470D0 (fr)
WO (1) WO2000009084A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
KR100951750B1 (ko) 2001-11-01 2010-04-09 노바르티스 아게 분무 건조 방법 및 그 조성물
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
BR102012011209A2 (pt) * 2012-05-11 2014-03-25 Bioactive Biomateriais Ltda Material tridimensional polimérico biodegradável e processo de preparo de material tridimensional polimérico biodegradável

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2657018A1 (fr) * 1990-01-12 1991-07-19 Merck Sharp & Dohme Composition ophtalmique fluide a base de microparticules lipidiques contenant au moins un principe actif et son procede de preparation.
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
IT1255076B (it) * 1992-04-01 1995-10-18 Inverni Della Beffa Spa Microsfere biodegradabili ad uso farmaceutico e cosmetico
AU680422B2 (en) * 1992-06-11 1997-07-31 Alkermes Controlled Therapeutics, Inc. Erythropoietin drug delivery system
FR2778847A1 (fr) * 1998-05-20 1999-11-26 Jean Pierre Perraud Implant injectable en sous gingival resorbable, constitue de microspheres a liberation prolongee et chargees en principes actifs et en suspension dans un gel vecteur

Also Published As

Publication number Publication date
GB9817470D0 (en) 1998-10-07
AU5182099A (en) 2000-03-06
WO2000009084A3 (fr) 2000-06-02
WO2000009084A2 (fr) 2000-02-24
JP2002522467A (ja) 2002-07-23
EP1105095A2 (fr) 2001-06-13

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Legal Events

Date Code Title Description
FZDE Discontinued