CA2346768A1 - La phytomique: une methode genomique de concevoir des compositions a base de plantes - Google Patents

La phytomique: une methode genomique de concevoir des compositions a base de plantes Download PDF

Info

Publication number
CA2346768A1
CA2346768A1 CA002346768A CA2346768A CA2346768A1 CA 2346768 A1 CA2346768 A1 CA 2346768A1 CA 002346768 A CA002346768 A CA 002346768A CA 2346768 A CA2346768 A CA 2346768A CA 2346768 A1 CA2346768 A1 CA 2346768A1
Authority
CA
Canada
Prior art keywords
herbal
herbal composition
batch
hbr
array
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002346768A
Other languages
English (en)
Inventor
Patrick C. Kung
Yung Chi Cheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2346768A1 publication Critical patent/CA2346768A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention concerne des outils et méthodologies nécessaires pour fournir des orientations en vue de la normalisation de compositions à base de plantes, afin de déterminer les composants spécifiques d'une telle composition, qui sont responsables d'une activité biologique particulière, pour prévoir les activités biologiques d'une composition particulière à base de plantes, et pour mettre au point des thérapies améliorées faisant intervenir des plantes. Cette invention propose des outils et méthodologies permettant de créer, gérer, améliorer et utiliser des réseaux HBR (réseaux de réponse biologique faisant intervenir des plantes), qui constituent des ensembles de données associés à des compositions particulières à base de plantes. Les réseaux HBR selon l'invention peuvent comprendre des informations relatives aux paramètres liés aux plantes des constituants à base de plantes, ainsi que des informations sur les marqueurs et sur la réponse biologique recueillies à la suite de l'exposition d'un écosystème à la composition à base de plantes.
CA002346768A 1998-10-23 1999-10-22 La phytomique: une methode genomique de concevoir des compositions a base de plantes Abandoned CA2346768A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10543598P 1998-10-23 1998-10-23
US60/105,435 1998-10-23
PCT/US1999/024851 WO2000024934A1 (fr) 1998-10-23 1999-10-22 La phytomique: une methode genomique de concevoir des compositions a base de plantes

Publications (1)

Publication Number Publication Date
CA2346768A1 true CA2346768A1 (fr) 2000-05-04

Family

ID=22305836

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002346768A Abandoned CA2346768A1 (fr) 1998-10-23 1999-10-22 La phytomique: une methode genomique de concevoir des compositions a base de plantes

Country Status (10)

Country Link
EP (1) EP1124991A1 (fr)
JP (1) JP2003521226A (fr)
KR (1) KR100470379B1 (fr)
CN (1) CN1335892A (fr)
AU (1) AU779424B2 (fr)
CA (1) CA2346768A1 (fr)
DE (1) DE1124991T1 (fr)
ES (1) ES2171371T1 (fr)
HK (1) HK1039964A1 (fr)
WO (1) WO2000024934A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066803A2 (fr) * 2000-03-09 2001-09-13 Yale University La phytomique: un procede genomique de concevoir des compositions a base de plantes
JP2006000113A (ja) * 2004-05-20 2006-01-05 Masatomo Sakurai 漢方医療の診断に用いる遺伝子およびその利用方法
KR102680200B1 (ko) * 2016-06-22 2024-07-02 예일 유니버시티 식물 의약을 위한 메커니즘 기반 품질 관리
CN108841928B (zh) * 2018-06-11 2021-11-23 河北医科大学 一种人类线粒体基因组甲基化检测试剂盒及其应用
CN110646497B (zh) * 2018-06-27 2021-10-29 中国科学院沈阳应用生态研究所 一种通过稳定氮同位素比值鉴定有机农产品的方法
CN110907580B (zh) * 2019-12-20 2022-02-25 厦门中药厂有限公司 一种保元汤的hplc特征图谱的检测方法
CN112305133B (zh) * 2020-12-25 2022-05-24 成都普思生物科技股份有限公司 一种测定天葵子中唐松草酚定含量的方法
CN112575005A (zh) * 2021-01-04 2021-03-30 昆明理工大学 一种提高烟草重金属镉胁迫抗性和降低镉富集的方法
CN114864016A (zh) * 2022-03-25 2022-08-05 广西壮族自治区药用植物园 一种药用植物化合物信息数据库建立方法及系统
JP7654293B1 (ja) * 2024-06-17 2025-04-01 バイオ - セラピー、フィジオロジカル システムズ フォー ヘルス ソシエタ ペル アチオニ 天然の治療用の製品又は有益な製品がその治療的な効果又は有益な効果を生理的な作用機構を介して発揮する時期を決定するための方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997027317A1 (fr) * 1996-01-23 1997-07-31 Affymetrix, Inc. Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US5569588A (en) * 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
US5777888A (en) * 1995-08-09 1998-07-07 Regents Of The University Of California Systems for generating and analyzing stimulus-response output signal matrices
WO1997013877A1 (fr) * 1995-10-12 1997-04-17 Lynx Therapeutics, Inc. Mesure de profils d'expression genique pour evaluer la toxicite
WO2000003725A1 (fr) * 1998-07-14 2000-01-27 Paracelsian, Inc. Procede d'identification et de confirmation de biofonctionnalite constante de compositions naturelles
US6780596B2 (en) * 1998-09-17 2004-08-24 Ashni Naturaceuticals, Inc. Methods for determining the activity of complex mixtures

Also Published As

Publication number Publication date
KR100470379B1 (ko) 2005-02-07
JP2003521226A (ja) 2003-07-15
AU1224900A (en) 2000-05-15
CN1335892A (zh) 2002-02-13
WO2000024934A1 (fr) 2000-05-04
KR20010099741A (ko) 2001-11-09
EP1124991A1 (fr) 2001-08-22
ES2171371T1 (es) 2002-09-16
HK1039964A1 (zh) 2002-05-17
AU779424B2 (en) 2005-01-27
DE1124991T1 (de) 2002-08-22

Similar Documents

Publication Publication Date Title
TWI275792B (en) Matrix methods for quantitatively analyzing and assessing the properties of botanical samples
Smelcerovic et al. Phytochemical analysis and genetic characterization of six Hypericum species from Serbia
US20030207270A1 (en) Phytomics: a genomic-based approach to herbal compositions
Jiang et al. Identification of potential anti-pneumonia pharmacological components of Glycyrrhizae Radix et Rhizoma after the treatment with Gan An He Ji oral liquid
Zhou et al. Comparison and evaluation of antimuscarinic and anti-inflammatory effects of five Bulbus fritillariae species based on UPLC-Q/TOF integrated dual-luciferase reporter assay, PCA and ANN analysis
Mao et al. Combining transcriptomic analysis and network pharmacology to explore the mechanism by which Shaofu Zhuyu decoction improves diabetes mellitus erectile dysfunction
Wang et al. In vivo and in vitro study on the regulatory mechanism of XiaoChaiHu decoction on PANoptosis in sepsis-induced cardiomyopathy
Qu et al. Transcriptome profiling revealed the potential mechanisms of Shen Lin Bai Zhu San n-butanol extract on DSS induced colitis in mice and LC-MS analysis
AU779424B2 (en) Phytomics: a genomic-based approach to herbal compositions
Li et al. Clinical trait-connected network analysis reveals transcriptional markers of active psoriasis treatment with Liangxue-Jiedu decoction
AU4556501A (en) Phytomics: a genomic-based approach to herbal compositions
Abdelmigid New trends in genotoxicity testing of herbal medicinal plants
Wen et al. Correlation analysis between genetic and chemical differences of Nardostachys jatamansi from different habitats in Ganzi Tibetan Autonomous Prefecture, Sichuan Province, China
Cho et al. Combination of UHPLC-MS/MS with context-specific network and cheminformatic approaches for identifying bioactivities and active components of propolis
US20010039022A1 (en) Methods for determining the activity of complex mixtures
AU2005201751A1 (en) Phytomics: a genomic-based approach to herbal compositions
Zheng et al. Shen-Ling-Bai-Zhu-San alleviates Crohn’s disease-like colitis by modulating fatty acid degradation via the peroxisome proliferation-activated receptor pathway: An integrated approach combining network pharmacology, microbiomics, metabolomics, proteomics, and experimental validation
TWI243210B (en) A quality control method for assessing herbal compositions
Zhao et al. Treatment of acute pharyngitis in rats with season tea decoctions from traditional Chinese medicine through a synergistic and subtle regulation of ARNTL and BHLHE40
Mirmazloum et al. Glycoside content in Rhodiola rosea L.: dynamics and expression pattern of genes involved in the synthesis of rosavins
Han et al. Comparative analysis of the influence of Fructus Ligustri Lucidi on a rat lumbar disc herniation model
Wang et al. Puerarin ameliorates alcoholic liver disease by regulating intestinal flora and MAPK/Nrf2 signalling pathways
Antoshechkin et al. Analysis of effects of the herbal preparation Circulat on gene expression levels in cultured human fibroblasts
Xu et al. Xiaojianzhong decoction inhibits gastric cancer progression and enhances 5-Fu efficacy by regulating the MAPK and PI3K-AKT signaling pathway
Lin et al. Integrating transcriptomics and network pharmacology to reveal the effect and mechanism of Bai-Jie-Jing-Xie ointment on improving skin inflammation of psoriasis

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued
FZDE Discontinued

Effective date: 20061023