CA2362924A1 - Proteines secretees et acides nucleiques codant pour elles - Google Patents

Proteines secretees et acides nucleiques codant pour elles Download PDF

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Publication number
CA2362924A1
CA2362924A1 CA002362924A CA2362924A CA2362924A1 CA 2362924 A1 CA2362924 A1 CA 2362924A1 CA 002362924 A CA002362924 A CA 002362924A CA 2362924 A CA2362924 A CA 2362924A CA 2362924 A1 CA2362924 A1 CA 2362924A1
Authority
CA
Canada
Prior art keywords
seq
tango
polypeptide
nucleic acid
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002362924A
Other languages
English (en)
Inventor
Thomas M. Barnes
Douglas A. Holtzman
John D. Sharp
Christopher C. Fraser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2362924A1 publication Critical patent/CA2362924A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des molécules d'acides nucléiques isolés, portant les désignations TANGO 216, TANGO 261, TANGO 262, TANGO 266, et TANGO 267. Ces molécules d'acides nucléiques codent pour des protéines totalement sécrétées et transmembranaires. L'invention concerne également des molécules d'acides nucléiques antisens, des vecteurs d'expression contenant les molécules d'acides nucléiques de l'invention, des cellules hôtes dans lesquelles ont été introduits les vecteurs d'expression, et des animaux transgéniques non humains dans lesquels a été introduite ou interrompue une molécule d'acide nucléique de l'invention. L'invention concerne en outre des polypeptides isolés, des polypeptides de fusion, des peptides antigènes et anticorps. L'invention concerne enfin des techniques de diagnostic, de recherche systématique et de traitement mettant en oeuvre les compositions de l'invention.
CA002362924A 1999-03-01 2000-03-01 Proteines secretees et acides nucleiques codant pour elles Abandoned CA2362924A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12245899P 1999-03-01 1999-03-01
US60/122,458 1999-03-01
PCT/US2000/005226 WO2000052022A1 (fr) 1999-03-01 2000-03-01 Proteines secretees et acides nucleiques codant pour elles

Publications (1)

Publication Number Publication Date
CA2362924A1 true CA2362924A1 (fr) 2000-09-08

Family

ID=22402831

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002362924A Abandoned CA2362924A1 (fr) 1999-03-01 2000-03-01 Proteines secretees et acides nucleiques codant pour elles

Country Status (5)

Country Link
EP (1) EP1173456A4 (fr)
JP (1) JP2002539773A (fr)
AU (1) AU3386800A (fr)
CA (1) CA2362924A1 (fr)
WO (1) WO2000052022A1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020132252A1 (en) 1997-06-16 2002-09-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7223727B2 (en) 1998-04-09 2007-05-29 Serono Genetics Institute S.A. GSSP4 polynucleotides and polypeptides and uses thereof
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
DK1247863T3 (da) * 1998-08-11 2006-05-15 Genentech Inc Slangegiftprotein A-homolog og nukleinsyre kodende derfor
EP1710299A3 (fr) * 1998-12-30 2007-01-10 Millennium Pharmaceuticals, Inc. Proteines secretées et polynucleotides codant pour ces proteines
JP2004522402A (ja) * 1999-06-02 2004-07-29 ジェネンテック・インコーポレーテッド 同一のものをコードする分泌及び膜貫通ポリペプチドと核酸
AU6976500A (en) * 1999-09-16 2001-04-17 Amgen Canada Inc. Nrage nucleic acids and polypeptides and uses thereof
US20090176722A9 (en) 2000-01-28 2009-07-09 Shiv Srivastava Androgen-regulated PMEPA1 gene and polypeptides
EP1302542B1 (fr) 2000-07-18 2007-06-13 Takeda Pharmaceutical Company Limited Nouveau peptide actif sur le plan physiologique et utilisation associee
RU2002110275A (ru) * 2000-08-22 2004-03-27 Дзе Брихэм Энд Уимен'З Хоспитал, Инк. (Us) Диагностика и лечение сердечно-сосудистых состояний
WO2002031143A2 (fr) * 2000-10-12 2002-04-18 The Texas A & M University System Sequences d'acides nucleiques codant des proteines cmg, proteines cmg et leurs procedes d'utilisation
AU2001296023A1 (en) * 2000-10-30 2002-05-15 Takeda Chemical Industries Ltd. Process for producing peptide
EP1506971A1 (fr) * 2000-11-03 2005-02-16 The Regents of the University of California Polypeptides prokinéticines; compositions et méthodes apparentées
WO2002036625A2 (fr) * 2000-11-03 2002-05-10 The Regents Of The University Of California Polypeptides de prokineticine, et methodes et compositions associees
WO2002057443A1 (fr) * 2001-01-22 2002-07-25 Takeda Chemical Industries, Ltd. Methode de production de ligand zaq
US20040072293A1 (en) * 2001-02-02 2004-04-15 Tetsuya Ohtaki Novel physiologically active peptide and use thereof
EP1357129A4 (fr) * 2001-02-02 2006-09-06 Takeda Pharmaceutical Nouveau peptide physiologiquement actif et son utilisation
AU2002307819A1 (en) * 2001-02-09 2002-09-19 Genset Gssp4 polynucleotides and polypeptides and uses thereof
CA2485138C (fr) 2002-05-10 2015-04-28 Henry M. Jackson Foundation For The Advancement Of Military Medicine Gene pmepa1 regule par les androgenes et procedes d'utilisation de ce dernier pour inhiber la croissance des cellules cancereuses
CA2500587A1 (fr) 2002-10-04 2004-04-22 The Regents Of The University Of California Criblage et procedes therapeutiques lies a la neurogenese
WO2004052277A2 (fr) 2002-12-05 2004-06-24 Wisconsin Alumni Research Foundation Antitoxines de l'anthrax
CN102225194B (zh) 2003-03-12 2014-07-16 健泰科生物技术公司 Bv8和/或EG-VEGF促进造血的用途
WO2007130627A2 (fr) 2006-05-04 2007-11-15 The Brigham And Women's Hospital, Inc. Il-33 utilisée pour le traitement et le diagnostic de maladies et de troubles
MX356367B (es) 2008-12-09 2018-05-25 Genentech Inc Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
CN121449718B (zh) * 2025-11-17 2026-07-17 中南大学湘雅二医院 Gckr基因转录本及其检测试剂、方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6607879B1 (en) * 1998-02-09 2003-08-19 Incyte Corporation Compositions for the detection of blood cell and immunological response gene expression

Also Published As

Publication number Publication date
EP1173456A1 (fr) 2002-01-23
JP2002539773A (ja) 2002-11-26
AU3386800A (en) 2000-09-21
EP1173456A4 (fr) 2005-10-12
WO2000052022A1 (fr) 2000-09-08

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 20040301