CA2387836C - Dispositif servant a prelever un specimen de l'intestin et son utilisation - Google Patents
Dispositif servant a prelever un specimen de l'intestin et son utilisation Download PDFInfo
- Publication number
- CA2387836C CA2387836C CA002387836A CA2387836A CA2387836C CA 2387836 C CA2387836 C CA 2387836C CA 002387836 A CA002387836 A CA 002387836A CA 2387836 A CA2387836 A CA 2387836A CA 2387836 C CA2387836 C CA 2387836C
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- CA
- Canada
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000005070 sampling Methods 0.000 title claims abstract description 58
- 230000000968 intestinal effect Effects 0.000 title claims abstract description 31
- 230000001681 protective effect Effects 0.000 claims abstract description 17
- 210000000936 intestine Anatomy 0.000 claims abstract description 16
- 239000012530 fluid Substances 0.000 claims abstract description 8
- 239000013566 allergen Substances 0.000 claims description 11
- 238000012360 testing method Methods 0.000 claims description 5
- 208000004262 Food Hypersensitivity Diseases 0.000 claims description 4
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- 230000007815 allergy Effects 0.000 claims description 4
- 235000020932 food allergy Nutrition 0.000 claims description 4
- 208000015943 Coeliac disease Diseases 0.000 claims description 3
- 239000012491 analyte Substances 0.000 claims description 3
- 238000006073 displacement reaction Methods 0.000 claims 1
- 238000011067 equilibration Methods 0.000 claims 1
- 239000000463 material Substances 0.000 description 8
- 210000000664 rectum Anatomy 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 239000011358 absorbing material Substances 0.000 description 6
- 238000003780 insertion Methods 0.000 description 6
- 230000037431 insertion Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 210000004400 mucous membrane Anatomy 0.000 description 6
- 210000000436 anus Anatomy 0.000 description 5
- 230000000112 colonic effect Effects 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 4
- 230000004054 inflammatory process Effects 0.000 description 4
- 210000004877 mucosa Anatomy 0.000 description 4
- 210000005070 sphincter Anatomy 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 102100028471 Eosinophil peroxidase Human genes 0.000 description 3
- 238000001574 biopsy Methods 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 239000011536 extraction buffer Substances 0.000 description 3
- 210000001035 gastrointestinal tract Anatomy 0.000 description 3
- 239000003550 marker Substances 0.000 description 3
- 230000010412 perfusion Effects 0.000 description 3
- 108090000695 Cytokines Proteins 0.000 description 2
- 102000004127 Cytokines Human genes 0.000 description 2
- 108010092408 Eosinophil Peroxidase Proteins 0.000 description 2
- 101710191360 Eosinophil cationic protein Proteins 0.000 description 2
- 108010068370 Glutens Proteins 0.000 description 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 2
- 208000037273 Pathologic Processes Diseases 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 210000005095 gastrointestinal system Anatomy 0.000 description 2
- 235000021312 gluten Nutrition 0.000 description 2
- 210000003714 granulocyte Anatomy 0.000 description 2
- 210000003630 histaminocyte Anatomy 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 210000004347 intestinal mucosa Anatomy 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000003448 neutrophilic effect Effects 0.000 description 2
- 231100000915 pathological change Toxicity 0.000 description 2
- 230000036285 pathological change Effects 0.000 description 2
- 230000009054 pathological process Effects 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 150000003180 prostaglandins Chemical class 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
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- 239000000376 reactant Substances 0.000 description 2
- 238000003325 tomography Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- LZZYPRNAOMGNLH-UHFFFAOYSA-M Cetrimonium bromide Chemical compound [Br-].CCCCCCCCCCCCCCCC[N+](C)(C)C LZZYPRNAOMGNLH-UHFFFAOYSA-M 0.000 description 1
- 102000057955 Eosinophil Cationic Human genes 0.000 description 1
- 102100040618 Eosinophil cationic protein Human genes 0.000 description 1
- 108010002352 Interleukin-1 Proteins 0.000 description 1
- 108090001005 Interleukin-6 Proteins 0.000 description 1
- 102000003896 Myeloperoxidases Human genes 0.000 description 1
- 108090000235 Myeloperoxidases Proteins 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 102000001400 Tryptase Human genes 0.000 description 1
- 108060005989 Tryptase Proteins 0.000 description 1
- 238000004026 adhesive bonding Methods 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 238000002052 colonoscopy Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 description 1
- 229960002986 dinoprostone Drugs 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 238000001839 endoscopy Methods 0.000 description 1
- 210000000222 eosinocyte Anatomy 0.000 description 1
- 230000002327 eosinophilic effect Effects 0.000 description 1
- 239000013568 food allergen Substances 0.000 description 1
- 238000002575 gastroscopy Methods 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 229960001340 histamine Drugs 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 239000003547 immunosorbent Substances 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000004848 nephelometry Methods 0.000 description 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 239000012858 resilient material Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000000439 tumor marker Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/04—Endoscopic instruments, e.g. catheter-type instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B2010/0061—Alimentary tract secretions, e.g. biliary, gastric, intestinal, pancreatic secretions
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endoscopes (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Dispositif servant à prélever un spécimen de l'intestin d'un patient humain ou animal et comprenant une partie de retenue (1) et une partie dilatable (2) supportée par la partie de retenue, et dont la surface présente une ou plusieurs zones de prélèvement de spécimen. La partie dilatable (2) à l'état non dilaté peut être insérée par voie rectale dans l'intestin, et retirée de la même façon, et, à l'état dilaté, lorsqu'elle est introduite dans l'intestin, cette partie dilatable peut venir en contact avec la paroi intestinale par au moins une zone de prélèvement (8, 14). Ce dispositif comprend, de plus, des moyens de protection (7a, 7b) servant à empêcher le contact de ladite zone ou desdites zones de prélèvement (8) avec la paroi intestinale et le fluide intestinal au moins quand la partie dilatable (2) à l'état non dilaté est en cours d'insertion par voie rectale dans l'intestin.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9903872A SE9903872D0 (sv) | 1999-10-26 | 1999-10-26 | Apparatus for intestinal sampling and use thereof |
| SE9903872-1 | 1999-10-26 | ||
| PCT/SE2000/002063 WO2001030243A1 (fr) | 1999-10-26 | 2000-10-24 | Dispositif servant a prelever un specimen de l'intestin et son utilisation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2387836A1 CA2387836A1 (fr) | 2001-05-03 |
| CA2387836C true CA2387836C (fr) | 2008-12-30 |
Family
ID=20417503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002387836A Expired - Fee Related CA2387836C (fr) | 1999-10-26 | 2000-10-24 | Dispositif servant a prelever un specimen de l'intestin et son utilisation |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1235519B1 (fr) |
| JP (1) | JP4810039B2 (fr) |
| AT (1) | ATE390887T1 (fr) |
| AU (1) | AU777463B2 (fr) |
| CA (1) | CA2387836C (fr) |
| DE (1) | DE60038499T2 (fr) |
| ES (1) | ES2304356T3 (fr) |
| SE (1) | SE9903872D0 (fr) |
| WO (1) | WO2001030243A1 (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0415277D0 (en) | 2004-07-07 | 2004-08-11 | Colonix Ltd | Apparatus and method for sampling mucosal surfaces |
| IL270674B2 (en) * | 2017-05-19 | 2024-12-01 | Shalon Tidhar | Instruments and methods for collecting samples from the digestive system |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3877464A (en) * | 1972-06-07 | 1975-04-15 | Andrew R Vermes | Intra-uterine biopsy apparatus |
| IT1206532B (it) * | 1985-10-15 | 1989-04-27 | Marcucci Francesco | Metodo allergodiagnostico mucosale e relativo dispositivo per il rilievo in vivo delle ige specifiche e totali |
| US4735212A (en) * | 1986-07-01 | 1988-04-05 | Cordis Corporation | Multiple site fiber optic pressure transducer |
| SE455368B (sv) * | 1986-11-11 | 1988-07-11 | Roger Hellgren | Anordning for nedleggning i tunntarmen i och for intestinal aspiration/perfusion |
| SE9401883L (sv) * | 1994-06-01 | 1995-12-02 | Roger Haellgren | Sätt vid diagnosticering av födoämnesintolerans/allergi samt instrument för diagnostiseringen |
-
1999
- 1999-10-26 SE SE9903872A patent/SE9903872D0/xx unknown
-
2000
- 2000-10-24 WO PCT/SE2000/002063 patent/WO2001030243A1/fr not_active Ceased
- 2000-10-24 JP JP2001532666A patent/JP4810039B2/ja not_active Expired - Fee Related
- 2000-10-24 DE DE60038499T patent/DE60038499T2/de not_active Expired - Lifetime
- 2000-10-24 ES ES00973331T patent/ES2304356T3/es not_active Expired - Lifetime
- 2000-10-24 CA CA002387836A patent/CA2387836C/fr not_active Expired - Fee Related
- 2000-10-24 AT AT00973331T patent/ATE390887T1/de not_active IP Right Cessation
- 2000-10-24 AU AU11853/01A patent/AU777463B2/en not_active Ceased
- 2000-10-24 EP EP00973331A patent/EP1235519B1/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1235519A1 (fr) | 2002-09-04 |
| AU1185301A (en) | 2001-05-08 |
| AU777463B2 (en) | 2004-10-21 |
| CA2387836A1 (fr) | 2001-05-03 |
| DE60038499T2 (de) | 2009-04-09 |
| WO2001030243A1 (fr) | 2001-05-03 |
| SE9903872D0 (sv) | 1999-10-26 |
| ATE390887T1 (de) | 2008-04-15 |
| ES2304356T3 (es) | 2008-10-16 |
| JP2003512122A (ja) | 2003-04-02 |
| DE60038499D1 (de) | 2008-05-15 |
| JP4810039B2 (ja) | 2011-11-09 |
| EP1235519B1 (fr) | 2008-04-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |