CA2398251A1 - Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir) - Google Patents

Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir) Download PDF

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Publication number
CA2398251A1
CA2398251A1 CA002398251A CA2398251A CA2398251A1 CA 2398251 A1 CA2398251 A1 CA 2398251A1 CA 002398251 A CA002398251 A CA 002398251A CA 2398251 A CA2398251 A CA 2398251A CA 2398251 A1 CA2398251 A1 CA 2398251A1
Authority
CA
Canada
Prior art keywords
polypeptide
polynucleotide
seq
protein
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002398251A
Other languages
English (en)
Inventor
Bryan J. Boyle
Chiaoyun Kuo
Nancy K. Mize
Dana Haley-Vicente
Matthew C. Arterburn
Y. Tom Tang
Ping Zhou
Chenghua Liu
Vinod Asundi
Radoje T. Drmanac
George Yeung
Servando Palencia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Hyseq Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyseq Inc filed Critical Hyseq Inc
Publication of CA2398251A1 publication Critical patent/CA2398251A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des nouveaux polynucléotides et polypeptides codés par de tels polynucléotides ainsi que leurs mutants ou variants qui correspondent à un nouveau polypeptide humain sécrété semblable à un récepteur de leucocyte de type immunoglobuline. Ces polynucléotides renferment des séquences d'acide nucléique isolées de banques d'cADN préparées à partir d'une banque d'cADN préparée à partir d'un mARN de leucocyte humain (Laboratoires GIBCO) (SEQ ID NO:1, SEQ ID NO:16); d'un mARN du cerveau d'un nourrisson (Columbia University) (SEQ ID NO: 35); d'un mARN de glande mammaire humaine (Invitrogène) (SEQ ID NO: 47); et d'un mARN de moelle osseuse (Clontech) (SEQ ID NO: 63). D'autres aspects de l'invention concernent des vecteurs contenant des procédés de production de polypeptides humains sécrétés semblables à LIR, ainsi que des anticorps propres à de tels polypeptides.
CA002398251A 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir) Abandoned CA2398251A1 (fr)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US49140400A 2000-01-25 2000-01-25
US09/491,404 2000-01-25
US49691400A 2000-02-03 2000-02-03
US09/496,914 2000-02-03
US51970500A 2000-03-07 2000-03-07
US09/519,705 2000-03-07
US56087500A 2000-04-27 2000-04-27
US09/560,875 2000-04-27
US09/524,454 2000-05-19
US64261000A 2000-08-17 2000-08-17
US09/642,610 2000-08-17
US75151800A 2000-12-29 2000-12-29
US09/751,518 2000-12-29
PCT/US2001/002570 WO2001055335A2 (fr) 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir)

Publications (1)

Publication Number Publication Date
CA2398251A1 true CA2398251A1 (fr) 2001-08-02

Family

ID=46397760

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002398251A Abandoned CA2398251A1 (fr) 2000-01-25 2001-01-25 Procedes et materiaux se rapportant a des polypeptides et polynucleotides semblables a des recepteurs de leucocytes de type immunoglobuline (lir)

Country Status (4)

Country Link
EP (1) EP1261735A4 (fr)
AU (2) AU2001233003B2 (fr)
CA (1) CA2398251A1 (fr)
WO (1) WO2001055335A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002360376B2 (en) * 2001-11-14 2006-05-18 Immunex Corporation Modulation of LIR function to treat rheumatoid arthritis
AU2002952993A0 (en) * 2002-11-29 2002-12-12 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Therapeutic and diagnostic agents
EP1712563A4 (fr) * 2004-01-27 2008-05-28 Medical & Biol Lab Co Ltd Methode pour isoler des monocytes
BRPI0616438A2 (pt) * 2005-09-29 2012-12-25 Eisai R&D Man Co Ltd proteÍna, polinucleotÍdeo, anticorpo contra uma proteÍna secretora ou de membrana, ou um fragmento funcional do mesmo, hibridoma, agente terapÊutico para uma doenÇa autoimune, agente para inibir adesço de cÉlulas t, e, mÉtodo para triar uma substÂncia
JP5947727B2 (ja) 2010-01-20 2016-07-06 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 抗ｉｌｔ５抗体およびｉｌｔ５結合抗体断片による免疫調節
AU2011207253B2 (en) 2010-01-20 2015-02-12 Merck Sharp & Dohme Corp. Anti-ILT5 antibodies and ILT5-binding antibody fragments
KR20170080579A (ko) 2014-10-01 2017-07-10 플랜트 헬스 케어, 인코포레이티드 파괴된 과민성 반응 박스를 갖는 유발제 펩티드 및 그의 용도
JP2017530197A (ja) 2014-10-01 2017-10-12 プラント ヘルス ケア インコーポレイテッド 過敏感反応エリシターペプチド及びその使用
WO2017176588A1 (fr) 2016-04-06 2017-10-12 Plant Health Care, Inc. Microbes bénéfiques pour l'administration de peptides effecteurs ou de protéines effectrices et leur utilisation
PL3439682T3 (pl) 2016-04-06 2025-12-01 Plant Health Care, Inc. Peptydy pochodzące od czynnika wywołującego odpowiedź nadwrażliwości i ich stosowanie

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001509030A (ja) * 1997-01-21 2001-07-10 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド Ｆｃレセプターおよびポリペプチド
JP2001519666A (ja) * 1997-04-10 2001-10-23 ジェネティックス・インスチチュート・インコーポレーテッド 分泌発現配列タグ（ｓＥＳＴｓ）
US6448035B1 (en) * 1997-04-24 2002-09-10 Immunex Corporation Family of immunoregulators designated leukocyte immunoglobulin-like receptor (LIR)
US6020161A (en) * 1997-08-19 2000-02-01 Smithkline Beecham Corporation PIGR-1, a member of immunoglobulin gene superfamily
EP0905237A3 (fr) * 1997-08-25 1999-12-22 Smithkline Beecham Corporation PIGR-2 appartenant au sous-ordre des immunoglobulines
AU2757500A (en) * 1999-02-10 2000-08-29 Human Genome Sciences, Inc. 33 human secreted proteins
WO2000078962A1 (fr) * 1999-06-18 2000-12-28 Immunex Corporation Recepteur de surface de leucocyte (lsr), un adnc de la superfamille des ig exprime dans les leucocytes humains
WO2001000673A1 (fr) * 1999-06-30 2001-01-04 Millennium Pharmaceuticals, Inc. Proteines associees aux membranes et secretees, et leurs utilisations
AU6906800A (en) * 1999-08-17 2001-03-13 Incyte Genomics, Inc. Membrane associated proteins

Also Published As

Publication number Publication date
AU3300301A (en) 2001-08-07
EP1261735A2 (fr) 2002-12-04
WO2001055335A2 (fr) 2001-08-02
AU2001233003B2 (en) 2006-02-09
WO2001055335A3 (fr) 2002-03-07
EP1261735A4 (fr) 2005-04-06

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EEER Examination request
FZDE Discontinued