CA2456626C - Microstructures for delivering a composition cutaneously to skin using rotatable structures - Google Patents

Microstructures for delivering a composition cutaneously to skin using rotatable structures Download PDF

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Publication number
CA2456626C
CA2456626C CA002456626A CA2456626A CA2456626C CA 2456626 C CA2456626 C CA 2456626C CA 002456626 A CA002456626 A CA 002456626A CA 2456626 A CA2456626 A CA 2456626A CA 2456626 C CA2456626 C CA 2456626C
Authority
CA
Canada
Prior art keywords
skin
microelements
substrate
microelement
rotatable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002456626A
Other languages
English (en)
French (fr)
Other versions
CA2456626A1 (en
Inventor
Vladimir Gartstein
Faiz Feisal Sherman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corium LLC
Original Assignee
Corium International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/952,391 external-priority patent/US7108681B2/en
Priority claimed from US10/216,148 external-priority patent/US20040087992A1/en
Application filed by Corium International Inc filed Critical Corium International Inc
Publication of CA2456626A1 publication Critical patent/CA2456626A1/en
Application granted granted Critical
Publication of CA2456626C publication Critical patent/CA2456626C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/32Surgical cutting instruments
    • A61B17/322Skin grafting apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00761Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00765Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/32Surgical cutting instruments
    • A61B2017/320004Surgical cutting instruments abrasive
    • A61B2017/320008Scrapers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Surgical Instruments (AREA)
CA002456626A 2001-09-14 2002-09-13 Microstructures for delivering a composition cutaneously to skin using rotatable structures Expired - Lifetime CA2456626C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/952,391 2001-09-14
US09/952,391 US7108681B2 (en) 2000-10-16 2001-09-14 Microstructures for delivering a composition cutaneously to skin
US10/216,148 US20040087992A1 (en) 2002-08-09 2002-08-09 Microstructures for delivering a composition cutaneously to skin using rotatable structures
US10/216,148 2002-08-09
PCT/US2002/029228 WO2003024518A2 (en) 2001-09-14 2002-09-13 Microstructures for delivering a composition cutaneously to skin using rotatable structures

Publications (2)

Publication Number Publication Date
CA2456626A1 CA2456626A1 (en) 2003-03-27
CA2456626C true CA2456626C (en) 2009-01-20

Family

ID=26910709

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002456626A Expired - Lifetime CA2456626C (en) 2001-09-14 2002-09-13 Microstructures for delivering a composition cutaneously to skin using rotatable structures

Country Status (5)

Country Link
EP (1) EP1425064A2 (de)
JP (1) JP2005503210A (de)
AU (1) AU2002333636A1 (de)
CA (1) CA2456626C (de)
WO (1) WO2003024518A2 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
US7131987B2 (en) 2000-10-16 2006-11-07 Corium International, Inc. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7108681B2 (en) 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US6663820B2 (en) 2001-03-14 2003-12-16 The Procter & Gamble Company Method of manufacturing microneedle structures using soft lithography and photolithography
IL152912A0 (en) * 2002-11-18 2003-06-24 Nanopass Ltd Micro needle systems
US7578954B2 (en) 2003-02-24 2009-08-25 Corium International, Inc. Method for manufacturing microstructures having multiple microelements with through-holes
WO2005007020A2 (en) 2003-07-03 2005-01-27 Corium International, Inc. Wound dressing, ingredient delivery device and iv hold-down, and method relating to same
CN100478040C (zh) 2003-11-10 2009-04-15 新加坡科技研究局 微型针以及微型针的制造
JP2005246595A (ja) * 2004-03-05 2005-09-15 Ritsumeikan マイクロニードルアレイ及びその製造方法
AU2005243727B2 (en) 2004-04-12 2011-04-28 Allergan, Inc. Multi-site injection system
EP1740108B1 (de) 2004-04-30 2010-05-19 Gyung Su Cho Elektrische dermabrasionsvorrichtung
US20070078414A1 (en) 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
US9987475B2 (en) 2006-07-03 2018-06-05 Lotte Chemical Corporation Micro needle roller assembly
JP4821993B2 (ja) * 2006-07-21 2011-11-24 芳一 飛永 マイクロインプリメント及びその製造方法
KR200451185Y1 (ko) 2007-02-15 2010-12-01 (주)클리니칼레졸루션아시아 모듈식 마이크로니들 롤러
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
CN101888826A (zh) * 2007-12-07 2010-11-17 Dts罗勒斯株式会社 盘针辊轮
WO2009130926A1 (ja) * 2008-04-22 2009-10-29 南部化成株式会社 経皮投薬方法、ニードル形成体及び経皮投薬装置
WO2009144624A1 (en) * 2008-05-28 2009-12-03 Koninklijke Philips Electronics N.V. Device for controlled drug delivery
JP5357257B2 (ja) * 2008-09-03 2013-12-04 ディーティーエスラッブ カンパニー リミテッド 皮膚刺激器
US20110144591A1 (en) * 2009-12-11 2011-06-16 Ross Russell F Transdermal Delivery Device
JP6327852B2 (ja) 2010-05-04 2018-05-23 コリウム インターナショナル, インコーポレイテッド 微小突起アレイを使用した副甲状腺ホルモンの経皮送達のための方法及びデバイス
GB201107642D0 (en) 2011-05-09 2011-06-22 Univ Cork Method
ES2786508T3 (es) 2012-06-12 2020-10-13 Hisamitsu Pharmaceutical Co Lámina de microagujas
KR102238227B1 (ko) * 2012-12-06 2021-04-12 에스알쥐아이 홀딩스 엘엘씨 픽셀 어레이 의료용 장치 및 방법
AU2013364053B2 (en) 2012-12-21 2018-08-30 Corium Pharma Solutions, Inc. Microarray for delivery of therapeutic agent and methods of use
CA2903748C (en) 2013-03-12 2021-11-02 Corium International, Inc. Microprojection applicators
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
AU2014237279B2 (en) 2013-03-15 2018-11-22 Corium Pharma Solutions, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
BR112015022625B1 (pt) 2013-03-15 2023-01-31 Corium, Inc Aparelho de microestrutura para entrega de agente terapêutico
WO2014203911A1 (ja) 2013-06-18 2014-12-24 久光製薬株式会社 アプリケータ
US10039911B2 (en) 2013-06-19 2018-08-07 Hisamitsu Pharmaceutical Co., Inc. Applicator
US9694142B2 (en) 2013-09-03 2017-07-04 Visage Sculpture, PLLC Device for percutaneous delivery of therapeutic agents, and a method for its use
EP3042690B1 (de) 2013-09-06 2021-04-14 Hisamitsu Pharmaceutical Co., Inc. Mikronadelfolie
KR102135495B1 (ko) 2014-02-27 2020-07-17 히사미쓰 세이야꾸 가부시키가이샤 마이크로 니들·시트
WO2016036866A1 (en) 2014-09-04 2016-03-10 Corium International, Inc. Microstructure array, methods of making, and methods of use
CN106999702B (zh) 2014-12-05 2020-07-10 久光制药株式会社 微针装置系统
US10004887B2 (en) * 2015-02-18 2018-06-26 Alma Therapeutics Ltd. Transdermal delivery assembly
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP6799005B2 (ja) 2015-12-15 2020-12-09 久光製薬株式会社 マイクロニードル・シート
EP3508247B1 (de) 2016-09-01 2024-08-14 Hisamitsu Pharmaceutical Co., Inc. Mikronadelblech
KR101906336B1 (ko) * 2018-03-22 2018-10-10 한국바이오기술공사(주) 펌프 내장형 니들 디스크 롤러 장치
CN109925590B (zh) * 2019-03-28 2021-10-08 吴晓苏 一种耦合剂快速刷涂及擦拭装置
CN218685709U (zh) * 2021-12-23 2023-03-24 苏州纳生微电子有限公司 微针阵列芯片

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4637758Y1 (de) * 1967-12-13 1971-12-27
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
DE2319591C2 (de) * 1973-04-18 1982-02-25 Kirchner & Wilhelm, 7000 Stuttgart Medizinischer Apparat
FR2232331B1 (de) * 1973-06-06 1978-03-24 Guerin A Ets
FR2535602B1 (fr) * 1982-11-05 1986-06-13 Stallergenes Lab Dispositif scarificateur
US4583982A (en) * 1984-08-24 1986-04-22 Vlock D G Fluid dispenser
CA2016900A1 (en) * 1989-07-06 1991-01-06 Ronald J. Filipski Tines structure in clinical applicator
JP2646766B2 (ja) * 1989-11-08 1997-08-27 日本電気株式会社 皮膚角層の除去器具
JP3189337B2 (ja) * 1991-11-08 2001-07-16 日本電気株式会社 皮膚角層の除去器具および除去方法
US5611806A (en) * 1994-05-23 1997-03-18 Samsung Electro-Mechanics Co., Ltd. Skin perforating device for transdermal medication
CA2149836C (en) * 1994-05-23 1999-07-06 Sang Bae Choi Perforating device for dermal administration
EP0796128B1 (de) * 1994-12-09 1999-03-10 Novartis AG Transdermales system
US5948488A (en) * 1996-04-30 1999-09-07 3M Innovative Properties Company Glittering cube-corner article
ES2200187T3 (es) * 1996-07-03 2004-03-01 Altea Therapeutics Corporation Microporacion mecanica multiple de la piel o de la mucosa.
JP3097600B2 (ja) * 1997-05-30 2000-10-10 日本電気株式会社 角質層穿刺装置
US5938684A (en) * 1997-12-09 1999-08-17 Sierra Self Healing Products, Inc. Accupressure device for therapeutic relief
WO1999029364A1 (en) * 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
DE69921489T2 (de) * 1998-08-31 2005-10-27 Johnson & Johnson Consumer Companies, Inc. Elektrotransportvorrichtung mit klingen
AU2189400A (en) * 1998-12-18 2000-07-03 Minimed, Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin

Also Published As

Publication number Publication date
CA2456626A1 (en) 2003-03-27
JP2005503210A (ja) 2005-02-03
EP1425064A2 (de) 2004-06-09
AU2002333636A1 (en) 2003-04-01
WO2003024518A2 (en) 2003-03-27
WO2003024518A3 (en) 2003-09-25

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Effective date: 20220913