CA2520945A1 - Evaluation des lesions neuronales a partir de prelevements sanguins - Google Patents

Evaluation des lesions neuronales a partir de prelevements sanguins Download PDF

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Publication number
CA2520945A1
CA2520945A1 CA002520945A CA2520945A CA2520945A1 CA 2520945 A1 CA2520945 A1 CA 2520945A1 CA 002520945 A CA002520945 A CA 002520945A CA 2520945 A CA2520945 A CA 2520945A CA 2520945 A1 CA2520945 A1 CA 2520945A1
Authority
CA
Canada
Prior art keywords
nfdp
antibody
injury
sample
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002520945A
Other languages
English (en)
Other versions
CA2520945C (fr
Inventor
Gerry Shaw
Brian R. Pike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida Research Foundation Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2520945A1 publication Critical patent/CA2520945A1/fr
Application granted granted Critical
Publication of CA2520945C publication Critical patent/CA2520945C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA2520945A 2003-03-31 2004-03-26 Evaluation des lesions neuronales a partir de prelevements sanguins Expired - Fee Related CA2520945C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45928603P 2003-03-31 2003-03-31
US60/459,286 2003-03-31
PCT/US2004/009114 WO2004091379A2 (fr) 2003-03-31 2004-03-26 Evaluation des lesions neuronales a partir de prelevements sanguins

Publications (2)

Publication Number Publication Date
CA2520945A1 true CA2520945A1 (fr) 2004-10-28
CA2520945C CA2520945C (fr) 2014-03-25

Family

ID=33299668

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2520945A Expired - Fee Related CA2520945C (fr) 2003-03-31 2004-03-26 Evaluation des lesions neuronales a partir de prelevements sanguins

Country Status (10)

Country Link
US (3) US20040241762A1 (fr)
EP (1) EP1613204B1 (fr)
JP (1) JP4557971B2 (fr)
AT (1) ATE440286T1 (fr)
AU (1) AU2004229317B2 (fr)
CA (1) CA2520945C (fr)
DE (1) DE602004022645D1 (fr)
DK (1) DK1613204T3 (fr)
ES (1) ES2332136T3 (fr)
WO (1) WO2004091379A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2367311T3 (es) * 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales.
WO2007139866A2 (fr) * 2006-05-24 2007-12-06 The University Of Miami Procédé de tri et système pour estimer la gravité d'une blessure chez des patients en phase critique
US20100159615A1 (en) * 2006-12-27 2010-06-24 Haruo Matsuda Immunological detection method using avian antibody
WO2012005588A2 (fr) * 2010-07-07 2012-01-12 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg Nouveaux biomarqueurs pour détecter la perte neuronale
EP3129780A4 (fr) * 2014-04-07 2017-12-13 Iron Horse Diagnostics Inc. Biomarqueurs d'état neurodégénératif et de lésion cérébrale traumatique, méthodes et systèmes
CN112823048A (zh) * 2018-07-27 2021-05-18 维拉维斯公司 消除和富集的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU86652A1 (de) * 1986-11-10 1988-06-13 Progen Biotechnik Gmbh Verfahren zum auffinden von gewebslaesionen
EP0378924B1 (fr) * 1988-12-21 1996-11-13 The General Hospital Corporation Détection de maladies ou dysfonctions neurologiques
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
GB9719879D0 (en) * 1997-09-19 1997-11-19 Neuropa Ltd Protein
US6589746B1 (en) * 1999-10-21 2003-07-08 University Of Cincinnati Method of detecting axonally-derived protein tau in patients with traumatic CNS injury

Also Published As

Publication number Publication date
CA2520945C (fr) 2014-03-25
EP1613204B1 (fr) 2009-08-19
EP1613204A4 (fr) 2007-04-04
US20040241762A1 (en) 2004-12-02
US20160349272A1 (en) 2016-12-01
WO2004091379A3 (fr) 2005-12-22
ATE440286T1 (de) 2009-09-15
AU2004229317B2 (en) 2012-01-12
JP2006522336A (ja) 2006-09-28
US20100184105A1 (en) 2010-07-22
DE602004022645D1 (de) 2009-10-01
AU2004229317A1 (en) 2004-10-28
DK1613204T3 (da) 2009-12-07
JP4557971B2 (ja) 2010-10-06
ES2332136T3 (es) 2010-01-27
EP1613204A2 (fr) 2006-01-11
HK1085538A1 (en) 2006-08-25
WO2004091379A2 (fr) 2004-10-28

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MKLA Lapsed

Effective date: 20160329