CA2521993A1 - Formes cristallines de sel hemicalcique d'acide¬r-(r*,r*)|-2-(4-fluorop henyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-¬(phenylamino) carbonyl|-1h-pyrrole-1-heptanoique (2:1)(atorvastatine) - Google Patents

Formes cristallines de sel hemicalcique d'acide¬r-(r*,r*)|-2-(4-fluorop henyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-¬(phenylamino) carbonyl|-1h-pyrrole-1-heptanoique (2:1)(atorvastatine) Download PDF

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Publication number
CA2521993A1
CA2521993A1 CA002521993A CA2521993A CA2521993A1 CA 2521993 A1 CA2521993 A1 CA 2521993A1 CA 002521993 A CA002521993 A CA 002521993A CA 2521993 A CA2521993 A CA 2521993A CA 2521993 A1 CA2521993 A1 CA 2521993A1
Authority
CA
Canada
Prior art keywords
atorvastatin
broad
crystalline form
hydrate
ray powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002521993A
Other languages
English (en)
Inventor
Stephen Robert Byrn
David Andrew Coates
Karen Sue Gushurst
Henry Grant Ii Morrison
Aeri Park
Petinka Ivanova Vlahova
Zheng Jane Li
Joseph Francis Krzyzaniak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35452260&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2521993(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Priority claimed from CA002450111A external-priority patent/CA2450111C/fr
Publication of CA2521993A1 publication Critical patent/CA2521993A1/fr
Abandoned legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CA002521993A 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide¬r-(r*,r*)|-2-(4-fluorop henyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-¬(phenylamino) carbonyl|-1h-pyrrole-1-heptanoique (2:1)(atorvastatine) Abandoned CA2521993A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30204901P 2001-06-29 2001-06-29
US60/302,049 2001-06-29
CA002450111A CA2450111C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002450111A Division CA2450111C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)

Publications (1)

Publication Number Publication Date
CA2521993A1 true CA2521993A1 (fr) 2003-01-16

Family

ID=35452260

Family Applications (14)

Application Number Title Priority Date Filing Date
CA002521833A Expired - Fee Related CA2521833C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002522899A Expired - Fee Related CA2522899C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521828A Expired - Fee Related CA2521828C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521933A Expired - Fee Related CA2521933C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521993A Abandoned CA2521993A1 (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide¬r-(r*,r*)|-2-(4-fluorop henyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-¬(phenylamino) carbonyl|-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521980A Expired - Fee Related CA2521980C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide[r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521776A Expired - Fee Related CA2521776C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521887A Expired - Fee Related CA2521887C (fr) 2001-06-29 2002-05-21 Crystalline forms of [r-(r*,r*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid calcium salt(2:1)(atorvastatin)
CA002521891A Expired - Fee Related CA2521891C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521953A Expired - Fee Related CA2521953C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521792A Expired - Fee Related CA2521792C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521958A Expired - Fee Related CA2521958C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521908A Expired - Fee Related CA2521908C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521956A Expired - Fee Related CA2521956C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)

Family Applications Before (4)

Application Number Title Priority Date Filing Date
CA002521833A Expired - Fee Related CA2521833C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002522899A Expired - Fee Related CA2522899C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521828A Expired - Fee Related CA2521828C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521933A Expired - Fee Related CA2521933C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)

Family Applications After (9)

Application Number Title Priority Date Filing Date
CA002521980A Expired - Fee Related CA2521980C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide[r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521776A Expired - Fee Related CA2521776C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521887A Expired - Fee Related CA2521887C (fr) 2001-06-29 2002-05-21 Crystalline forms of [r-(r*,r*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid calcium salt(2:1)(atorvastatin)
CA002521891A Expired - Fee Related CA2521891C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521953A Expired - Fee Related CA2521953C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521792A Expired - Fee Related CA2521792C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521958A Expired - Fee Related CA2521958C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521908A Expired - Fee Related CA2521908C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)
CA002521956A Expired - Fee Related CA2521956C (fr) 2001-06-29 2002-05-21 Formes cristallines de sel hemicalcique d'acide [r-(r*,r*)]-2-(4-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoique (2:1)(atorvastatine)

Country Status (1)

Country Link
CA (14) CA2521833C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8080672B2 (en) 2005-12-13 2011-12-20 Teva Pharmaceutical Industries Ltd. Crystal form of atorvastatin hemi-calcium and processes for preparation thereof

Also Published As

Publication number Publication date
CA2521908A1 (fr) 2003-01-16
CA2521887A1 (fr) 2003-01-16
CA2522899C (fr) 2006-04-25
CA2521776A1 (fr) 2003-01-16
CA2521958A1 (fr) 2003-01-16
CA2521828C (fr) 2006-04-25
CA2521933C (fr) 2006-03-21
CA2521980A1 (fr) 2003-01-16
CA2522899A1 (fr) 2003-01-16
CA2521887C (fr) 2006-04-25
CA2521833A1 (fr) 2003-01-16
CA2521792A1 (fr) 2003-01-16
CA2521776C (fr) 2006-04-25
CA2521833C (fr) 2006-04-25
CA2521980C (fr) 2006-08-29
CA2521828A1 (fr) 2003-01-16
CA2521891C (fr) 2006-04-25
CA2521933A1 (fr) 2003-01-16
CA2521958C (fr) 2006-08-29
CA2521908C (fr) 2006-04-25
CA2521956A1 (fr) 2003-01-16
CA2521891A1 (fr) 2003-01-16
CA2521953C (fr) 2006-03-14
CA2521953A1 (fr) 2003-01-16
CA2521956C (fr) 2006-04-25
CA2521792C (fr) 2006-04-25

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