CA2564800C - Systemes, dispositifs et procedes de relargage electrocinetique de medicament - Google Patents

Systemes, dispositifs et procedes de relargage electrocinetique de medicament Download PDF

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Publication number
CA2564800C
CA2564800C CA2564800A CA2564800A CA2564800C CA 2564800 C CA2564800 C CA 2564800C CA 2564800 A CA2564800 A CA 2564800A CA 2564800 A CA2564800 A CA 2564800A CA 2564800 C CA2564800 C CA 2564800C
Authority
CA
Canada
Prior art keywords
pump
reservoir
fluid
electrodes
power source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2564800A
Other languages
English (en)
Other versions
CA2564800A1 (fr
Inventor
Deon S. Anex
Phillip H. Paul
David W. Neyer
Edwin K. Hlavka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eksigent Technologies LLC
Original Assignee
Eksigent Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eksigent Technologies LLC filed Critical Eksigent Technologies LLC
Publication of CA2564800A1 publication Critical patent/CA2564800A1/fr
Application granted granted Critical
Publication of CA2564800C publication Critical patent/CA2564800C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
    • A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons flexible
    • A61M5/1483—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons flexible using flexible bags externally pressurised by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/006—Micropumps
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
    • F04B43/04—Pumps having electric drive
    • F04B43/043—Micropumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons with secondary fluid driving or regulating the infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic using feedback of body parameters, e.g. blood sugar or pressure

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Dermatology (AREA)
  • External Artificial Organs (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Micromachines (AREA)
  • Electrotherapy Devices (AREA)
CA2564800A 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament Expired - Fee Related CA2564800C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56449704P 2004-04-21 2004-04-21
US60/564,497 2004-04-21
PCT/US2005/013728 WO2005113419A2 (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament

Publications (2)

Publication Number Publication Date
CA2564800A1 CA2564800A1 (fr) 2005-12-01
CA2564800C true CA2564800C (fr) 2014-04-15

Family

ID=35428903

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2564800A Expired - Fee Related CA2564800C (fr) 2004-04-21 2005-04-21 Systemes, dispositifs et procedes de relargage electrocinetique de medicament

Country Status (6)

Country Link
EP (1) EP1740497A4 (fr)
JP (1) JP4646976B2 (fr)
CN (1) CN101365885B (fr)
AU (1) AU2005245347A1 (fr)
CA (1) CA2564800C (fr)
WO (1) WO2005113419A2 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2316505B1 (fr) * 2006-03-14 2017-01-18 University Of Southern California Dispositif Mems de livraison d'agents therapeutiques
CN101432032A (zh) * 2006-04-28 2009-05-13 皇家飞利浦电子股份有限公司 具有至少一种可充电材料的渗透泵
US8694077B2 (en) 2006-10-06 2014-04-08 The Cleveland Clinic Foundation Apparatus and method for targeting a body tissue
WO2008070262A2 (fr) 2006-10-06 2008-06-12 The Cleveland Clinic Foundation Appareil et procédé pour cibler un tissu cellulaire
GB2448493B (en) * 2007-04-16 2009-10-14 Dewan Fazlul Hoque Chowdhury Microneedle transdermal delivery device
JP2014523499A (ja) * 2011-05-05 2014-09-11 エクシジェント テクノロジーズ, エルエルシー 往復動界面動電ポンプの差動圧力制御のシステムおよび方法
JP2014519570A (ja) * 2011-05-05 2014-08-14 エクシジェント テクノロジーズ, エルエルシー 動電学的送出システム用のゲル結合部
US9956338B2 (en) 2012-07-06 2018-05-01 Sanofi-Aventis Deutschland Gmbh Drug delivery device
CA2889149C (fr) 2012-10-22 2017-05-16 The Cleveland Clinic Foundation Appareil et procede de ciblage d'un tissu corporel
JP6038194B2 (ja) * 2013-02-18 2016-12-07 テルモ株式会社 薬剤投与装置、薬剤投与システムおよびそれらの作動方法
CN106714871A (zh) * 2014-06-25 2017-05-24 魏民 用于给药的输液装置
US9416777B2 (en) 2014-09-26 2016-08-16 Becton, Dickinson And Company Control circuits for electrochemical pump with E-valves
JP2018501071A (ja) * 2014-12-30 2018-01-18 ミニパンプス・リミテッド・ライアビリティ・カンパニーMinipumps,Llc 移植可能な電解ダイヤフラムポンプ
KR101910932B1 (ko) * 2016-08-31 2018-10-23 이오플로우(주) 전기 삼투 펌프
KR101928297B1 (ko) * 2016-09-08 2018-12-12 이오플로우(주) 약액 주입장치
US20210330751A1 (en) * 2016-11-09 2021-10-28 PhysioLogic Devices, Inc. Insulins Compatible with New Generation Implantable Pumps
EP3338832A1 (fr) * 2016-12-23 2018-06-27 Sanofi-Aventis Deutschland GmbH Dispositif d'administration de médicaments
WO2018194041A1 (fr) * 2017-04-21 2018-10-25 ヨダカ技研株式会社 Dispositif de perfusion compact portatif
GB201714645D0 (en) 2017-09-12 2017-10-25 Osmotex Ag Method
US10809139B2 (en) * 2018-02-14 2020-10-20 Carefusion 303, Inc. Integrated sensor to monitor fluid delivery
JP6744527B1 (ja) * 2020-04-01 2020-08-19 アットドウス株式会社 薬液投与ユニット、薬液投与モジュール、薬液投与装置、及び投薬管理システム
TWI806182B (zh) * 2020-11-18 2023-06-21 潔霺生醫科技股份有限公司 多段式氣體致動供藥裝置及方法
WO2025262746A1 (fr) * 2024-06-17 2025-12-26 Ntt株式会社 Dispositif de transport de liquide médicamenteux
EP4684817A1 (fr) * 2024-07-23 2026-01-28 Manta MedTech LLC Dispositif implantable avec surveillance du deplacement du piston

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Publication number Priority date Publication date Assignee Title
US3923426A (en) * 1974-08-15 1975-12-02 Alza Corp Electroosmotic pump and fluid dispenser including same
DE2626348C3 (de) * 1976-06-11 1980-01-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
US4886514A (en) * 1985-05-02 1989-12-12 Ivac Corporation Electrochemically driven drug dispenser
JP2530220B2 (ja) * 1989-03-03 1996-09-04 日本特殊陶業株式会社 液体混合物分離装置
US5351164A (en) * 1991-10-29 1994-09-27 T.N. Frantsevich Institute For Problems In Materials Science Electrolytic double layer capacitor
KR19990022214A (ko) * 1995-06-06 1999-03-25 윌리암 제이. 버크 미세 전기도관 제조방법
US5961800A (en) * 1997-05-08 1999-10-05 Sarnoff Corporation Indirect electrode-based pumps
US6106685A (en) * 1997-05-13 2000-08-22 Sarnoff Corporation Electrode combinations for pumping fluids
US5942093A (en) * 1997-06-18 1999-08-24 Sandia Corporation Electro-osmotically driven liquid delivery method and apparatus
US6019882A (en) * 1997-06-25 2000-02-01 Sandia Corporation Electrokinetic high pressure hydraulic system
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US6409698B1 (en) * 2000-11-27 2002-06-25 John N. Robinson Perforate electrodiffusion pump
US6805783B2 (en) * 2000-12-13 2004-10-19 Toyo Technologies, Inc. Method for manipulating a solution using a ferroelectric electro-osmotic pump
US20030055380A1 (en) * 2001-09-19 2003-03-20 Flaherty J. Christopher Plunger for patient infusion device
US20030232203A1 (en) * 2002-01-18 2003-12-18 The Regents Of The University Of Michigan Porous polymers: compositions and uses thereof
US6719535B2 (en) * 2002-01-31 2004-04-13 Eksigent Technologies, Llc Variable potential electrokinetic device
WO2004036041A2 (fr) * 2002-10-18 2004-04-29 Eksigent Technologies, Llc Appareils electrocinetiques

Also Published As

Publication number Publication date
JP2008504794A (ja) 2008-02-14
EP1740497A2 (fr) 2007-01-10
CN101365885B (zh) 2011-08-03
EP1740497A4 (fr) 2015-11-11
WO2005113419A3 (fr) 2007-12-27
WO2005113419A2 (fr) 2005-12-01
CA2564800A1 (fr) 2005-12-01
CN101365885A (zh) 2009-02-11
JP4646976B2 (ja) 2011-03-09
AU2005245347A1 (en) 2005-12-01

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Effective date: 20170421