CA2616439C - Procedes et systemes pour surveiller de multiples signaux optiques a partir d'une unique source - Google Patents

Procedes et systemes pour surveiller de multiples signaux optiques a partir d'une unique source Download PDF

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Publication number
CA2616439C
CA2616439C CA2616439A CA2616439A CA2616439C CA 2616439 C CA2616439 C CA 2616439C CA 2616439 A CA2616439 A CA 2616439A CA 2616439 A CA2616439 A CA 2616439A CA 2616439 C CA2616439 C CA 2616439C
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Prior art keywords
optical
optical signals
different
fluid
signals
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CA2616439A1 (fr
Inventor
Paul Lundquist
Stephen Turner
Denis Zaccarin
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Pacific Biosciences of California Inc
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Pacific Biosciences of California Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2803—Investigating the spectrum using photoelectric array detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/30—Measuring the intensity of spectral lines directly on the spectrum itself
    • G01J3/36—Investigating two or more bands of a spectrum by separate detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"

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  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Geophysics And Detection Of Objects (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne des procédés et systèmes pour surveiller une pluralité de différents signaux optiques à partir d'une unique source de tels signaux, où chaque signal optique différent est séparé dans l'espace des autres signaux similaires et dirigé vers différents détecteurs ou emplacements sur un unique détecteur, dont la direction est généralement déterminée par l'utilisation d'un nombre réduit de composants optiques et/ou manipulations.
CA2616439A 2005-08-11 2006-08-10 Procedes et systemes pour surveiller de multiples signaux optiques a partir d'une unique source Active CA2616439C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/201,768 US7805081B2 (en) 2005-08-11 2005-08-11 Methods and systems for monitoring multiple optical signals from a single source
US11/201,768 2005-08-11
PCT/US2006/031387 WO2007019582A2 (fr) 2005-08-11 2006-08-10 Procédés et systèmes pour surveiller de multiples signaux optiques à partir d'une unique source

Publications (2)

Publication Number Publication Date
CA2616439A1 CA2616439A1 (fr) 2007-02-15
CA2616439C true CA2616439C (fr) 2012-03-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2616439A Active CA2616439C (fr) 2005-08-11 2006-08-10 Procedes et systemes pour surveiller de multiples signaux optiques a partir d'une unique source

Country Status (7)

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US (3) US7805081B2 (fr)
EP (1) EP1920277A4 (fr)
JP (1) JP2009505076A (fr)
CN (1) CN101536368A (fr)
AU (1) AU2006278236B2 (fr)
CA (1) CA2616439C (fr)
WO (1) WO2007019582A2 (fr)

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AU2006278236A1 (en) 2007-02-15
US20080226307A1 (en) 2008-09-18
CA2616439A1 (fr) 2007-02-15
WO2007019582A2 (fr) 2007-02-15
AU2006278236B2 (en) 2012-01-12
JP2009505076A (ja) 2009-02-05
US20100331212A1 (en) 2010-12-30
US7805081B2 (en) 2010-09-28
EP1920277A4 (fr) 2013-01-16
CN101536368A (zh) 2009-09-16
EP1920277A2 (fr) 2008-05-14
US20070036511A1 (en) 2007-02-15
WO2007019582A3 (fr) 2009-04-23

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