CA2629376C - Nouveaux inhibiteurs d'activite parp et leurs utilisations - Google Patents
Nouveaux inhibiteurs d'activite parp et leurs utilisations Download PDFInfo
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- CA2629376C CA2629376C CA2629376A CA2629376A CA2629376C CA 2629376 C CA2629376 C CA 2629376C CA 2629376 A CA2629376 A CA 2629376A CA 2629376 A CA2629376 A CA 2629376A CA 2629376 C CA2629376 C CA 2629376C
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- parp
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- inhibitor
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73658805P | 2005-11-14 | 2005-11-14 | |
| US60/736,588 | 2005-11-14 | ||
| PCT/IB2006/003224 WO2007054814A1 (fr) | 2005-11-14 | 2006-11-14 | Nouveaux inhibiteurs d’activite parp et leurs utilisations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2629376A1 CA2629376A1 (fr) | 2007-05-18 |
| CA2629376C true CA2629376C (fr) | 2015-06-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2629376A Expired - Fee Related CA2629376C (fr) | 2005-11-14 | 2006-11-14 | Nouveaux inhibiteurs d'activite parp et leurs utilisations |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9150628B2 (fr) |
| EP (1) | EP1948215B1 (fr) |
| JP (1) | JP5221368B2 (fr) |
| AT (1) | ATE540689T1 (fr) |
| CA (1) | CA2629376C (fr) |
| ES (1) | ES2380803T3 (fr) |
| WO (1) | WO2007054814A1 (fr) |
Families Citing this family (5)
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|---|---|---|---|---|
| EP2270510A1 (fr) * | 2009-07-02 | 2011-01-05 | EMBL (European Molecular Biology Laboratory) | Procédé de diagnostic pour prédire le risque de récurrence de cancer basé sur des isoformes macroH2A d'histone |
| CN108601793B (zh) | 2016-02-18 | 2024-08-23 | 伊维萨股份有限公司 | 使用5′-腺苷二磷酸核糖(adpr)的方法 |
| US11413288B2 (en) | 2017-11-01 | 2022-08-16 | Dana-Farber Cancer Institute, Inc. | Methods of treating cancers |
| WO2019191026A2 (fr) | 2018-03-27 | 2019-10-03 | Invirsa, Inc. | Méthodes pour l'utilisation de 5'-adénosine diphosphate ribose (adpr) |
| CN119736252B (zh) * | 2025-01-15 | 2025-06-27 | 首都医科大学 | 组蛋白变体macroH2A调控巨噬细胞功能在改善肿瘤免疫微环境中的应用 |
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| US5215738A (en) | 1985-05-03 | 1993-06-01 | Sri International | Benzamide and nicotinamide radiosensitizers |
| US5032617A (en) | 1985-05-03 | 1991-07-16 | Sri International | Substituted benzamide radiosensitizers |
| US5041653A (en) | 1985-05-03 | 1991-08-20 | Sri International | Substituted benzamide radiosensitizers |
| US5177075A (en) | 1988-08-19 | 1993-01-05 | Warner-Lambert Company | Substituted dihydroisoquinolinones and related compounds as potentiators of the lethal effects of radiation and certain chemotherapeutic agents; selected compounds, analogs and process |
| US5997856A (en) | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
| JP3140757B2 (ja) | 1989-02-06 | 2001-03-05 | デイナ・フアーバー・キヤンサー・インステイテユート | パッケージング欠陥hivプロウイルス、細胞系及びその使用 |
| GB9404485D0 (en) | 1994-03-09 | 1994-04-20 | Cancer Res Campaign Tech | Benzamide analogues |
| US5589483A (en) | 1994-12-21 | 1996-12-31 | Geron Corporation | Isoquinoline poly (ADP-ribose) polymerase inhibitors to treat skin diseases associated with cellular senescence |
| CA2225465A1 (fr) | 1995-08-02 | 1997-02-13 | Newcastle University Ventures Limited | Composes benzimidazole |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| GB9702701D0 (en) | 1997-02-01 | 1997-04-02 | Univ Newcastle Ventures Ltd | Quinazolinone compounds |
| US5981221A (en) * | 1997-03-26 | 1999-11-09 | Incyte Pharmaceuticals, Inc. | Histone fusion protein |
| CA2288306A1 (fr) | 1997-04-28 | 1998-11-05 | Rhone-Poulenc Rorer S.A. | Apport intratumoral, induit par un adenovirus, d'un antagoniste d'angiogenese destine au traitement de tumeurs |
| US20020022636A1 (en) | 1997-09-03 | 2002-02-21 | Jia-He Li | Oxo-substituted compounds, process of making, and compositions and methods for inhibiting parp activity |
| US6514983B1 (en) | 1997-09-03 | 2003-02-04 | Guilford Pharmaceuticals Inc. | Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage |
| US6635642B1 (en) | 1997-09-03 | 2003-10-21 | Guilford Pharmaceuticals Inc. | PARP inhibitors, pharmaceutical compositions comprising same, and methods of using same |
| US6197785B1 (en) | 1997-09-03 | 2001-03-06 | Guilford Pharmaceuticals Inc. | Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity |
| AU9298098A (en) | 1997-09-03 | 1999-03-22 | Guilford Pharmaceuticals Inc. | Amino-substituted compounds, methods, and compositions for inhibiting parp activity |
| WO1999011644A1 (fr) | 1997-09-03 | 1999-03-11 | Guilford Pharmaceuticals Inc. | Composes di-n-heterocycliques, et procedes et compositions permettant d'inhiber l'activite de la parp |
| US20020028813A1 (en) | 1997-09-03 | 2002-03-07 | Paul F. Jackson | Thioalkyl compounds, methods, and compositions for inhibiting parp activity |
| DE69941703D1 (de) | 1999-10-11 | 2010-01-07 | Pasteur Institut | Lentivirale Vektoren für die Herstellung von immunotherapeutischen Zusammensetzungen |
| FR2805821B1 (fr) | 2000-03-01 | 2004-01-16 | Diatos | Sequences d'acides amines facilitant la penetration d'une substance d'interet a l'interieur des cellules et/ou des noyaux cellulaires |
| CA2417454A1 (fr) | 2000-07-31 | 2002-02-07 | Active Motif | Administration de molecules dans des cellules par mediation peptidique |
| US6859652B2 (en) * | 2000-08-02 | 2005-02-22 | Mobile Satellite Ventures, Lp | Integrated or autonomous system and method of satellite-terrestrial frequency reuse using signal attenuation and/or blockage, dynamic assignment of frequencies and/or hysteresis |
| FR2849603B1 (fr) | 2003-01-07 | 2006-09-08 | Centre Nat Rech Scient | Composition pour le transport intracellulaire de macromolecules ou particules biologiques |
| JP2005052101A (ja) | 2003-08-06 | 2005-03-03 | Zoegene Corp | 新規タンパク質およびそれをコードするdna |
| EP1512696A1 (fr) | 2003-08-14 | 2005-03-09 | Diatos | Séquences d'acides aminés facilitant la pénétration d'une substance d'intérêt dans les cellules et/ou le noyau |
| EP1732596A2 (fr) * | 2004-03-11 | 2006-12-20 | Shantha West, Inc. | Utilisation therapeutique de l'antigene rm1 |
| WO2006119435A2 (fr) * | 2005-05-04 | 2006-11-09 | Invitrogen Corporation | Procedes pour identifier des biomarqueurs de cancer et des proteines phosphorylees |
| US7842467B1 (en) * | 2005-05-12 | 2010-11-30 | Celera Corporation | Breast disease targets and uses thereof |
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2006
- 2006-11-14 CA CA2629376A patent/CA2629376C/fr not_active Expired - Fee Related
- 2006-11-14 EP EP06820897A patent/EP1948215B1/fr not_active Not-in-force
- 2006-11-14 JP JP2008539534A patent/JP5221368B2/ja not_active Expired - Fee Related
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- 2006-11-14 AT AT06820897T patent/ATE540689T1/de active
- 2006-11-14 US US12/084,873 patent/US9150628B2/en not_active Expired - Fee Related
- 2006-11-14 WO PCT/IB2006/003224 patent/WO2007054814A1/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20100323974A1 (en) | 2010-12-23 |
| ES2380803T3 (es) | 2012-05-18 |
| WO2007054814A1 (fr) | 2007-05-18 |
| EP1948215A1 (fr) | 2008-07-30 |
| JP5221368B2 (ja) | 2013-06-26 |
| JP2009519216A (ja) | 2009-05-14 |
| EP1948215B1 (fr) | 2012-01-11 |
| US9150628B2 (en) | 2015-10-06 |
| ATE540689T1 (de) | 2012-01-15 |
| CA2629376A1 (fr) | 2007-05-18 |
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