CA2654840A1 - Squelettes biomimetiques lies a une biomolecule - Google Patents

Squelettes biomimetiques lies a une biomolecule Download PDF

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Publication number
CA2654840A1
CA2654840A1 CA002654840A CA2654840A CA2654840A1 CA 2654840 A1 CA2654840 A1 CA 2654840A1 CA 002654840 A CA002654840 A CA 002654840A CA 2654840 A CA2654840 A CA 2654840A CA 2654840 A1 CA2654840 A1 CA 2654840A1
Authority
CA
Canada
Prior art keywords
exemplary embodiment
composition
poly
polymer scaffold
fibers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002654840A
Other languages
English (en)
Inventor
Craig Hashi
Song Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2007/061253 external-priority patent/WO2007090102A2/fr
Application filed by Individual filed Critical Individual
Publication of CA2654840A1 publication Critical patent/CA2654840A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076—Chemical modification of the substrate
    • A61L33/0082—Chemical modification of the substrate by reacting with an organic compound other than heparin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
CA002654840A 2006-06-09 2007-06-11 Squelettes biomimetiques lies a une biomolecule Abandoned CA2654840A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US80435006P 2006-06-09 2006-06-09
US60/804,350 2006-06-09
US86178006P 2006-11-30 2006-11-30
US60/861,780 2006-11-30
PCT/US2007/061253 WO2007090102A2 (fr) 2006-01-27 2007-01-29 squelettes biomimetiques
USPCT/US2007/016253 2007-01-29
US11/668,448 US20070269481A1 (en) 2006-01-27 2007-01-29 Biomimetic Scaffolds
US11/668,448 2007-01-29
US92492607P 2007-06-05 2007-06-05
US60/924,926 2007-06-05
PCT/US2007/013736 WO2007146261A2 (fr) 2006-06-09 2007-06-11 Squelettes biomimétiques liés à une biomolécule

Publications (1)

Publication Number Publication Date
CA2654840A1 true CA2654840A1 (fr) 2007-12-21

Family

ID=40243723

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002654840A Abandoned CA2654840A1 (fr) 2006-06-09 2007-06-11 Squelettes biomimetiques lies a une biomolecule

Country Status (9)

Country Link
EP (1) EP2023852A4 (fr)
JP (1) JP2009540878A (fr)
KR (1) KR20090024249A (fr)
AU (1) AU2007258379A1 (fr)
CA (1) CA2654840A1 (fr)
IL (1) IL195801A0 (fr)
MX (1) MX2008015695A (fr)
RU (1) RU2009100654A (fr)
WO (1) WO2007146261A2 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007090102A2 (fr) * 2006-01-27 2007-08-09 The Regents Of The University Of California squelettes biomimetiques
EP2341865A4 (fr) 2008-10-07 2014-01-08 Nanonerve Inc Supports polymères fibreux multicouches, procédés de production et procédés d'utilisation
WO2010065265A2 (fr) 2008-11-25 2010-06-10 Edwards Lifesciences Corporation Appareil et procédé pour le déploiement in situ d'un dispositif prothétique
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
WO2011127478A1 (fr) 2010-04-09 2011-10-13 Nanovasc, Inc. Manchon pour greffon et procédé associé
BR112012026882A2 (pt) * 2010-05-17 2015-09-22 Pall Corp sistemas para semear células em sustentações tri-dimensionais
US9090863B2 (en) 2010-05-17 2015-07-28 Pall Corporation System for seeding cells onto three dimensional scaffolds
EP2412798A1 (fr) * 2010-07-27 2012-02-01 Gambro Lundia AB Membrane biomimétique pour cultiver des cellules
EP2646065A4 (fr) 2010-12-05 2016-03-23 Nanonerve Inc Supports polymères fibreux comprenant des fibres polymères structurées de manière diamétrale
EP2661243B1 (fr) * 2011-01-06 2022-10-12 Humacyte, Inc. Constructions obtenues par génie tissulaire
CN102698323B (zh) * 2012-05-14 2014-07-23 西南交通大学 一种抗凝血材料的制备方法
ES2470495B1 (es) 2012-12-19 2015-05-14 Universidad De Castilla La Mancha Materiales, métodos y dispositivos para estimular y dirigir la proliferación y migración de progenitores neurales y el crecimiento axonal y dendrítico
KR101526308B1 (ko) * 2013-01-23 2015-06-09 아주대학교산학협력단 생체 내 이식 적용 및 중장기 생체소재 분해 추적용 조영제가 화학적 결합된 생체소재 및 이의 제조방법
CN106103821B (zh) 2014-02-14 2018-03-02 日产化学工业株式会社 含有活性酯基的纤维制造用组合物及使用该纤维的细胞培养支架材料
CN104153123B (zh) * 2014-07-30 2016-08-24 东华大学 一种柔性氧化钛纳米纤维膜及其制备方法
CN104153124B (zh) * 2014-07-30 2016-11-02 东华大学 一种柔性稀土氧化物纳米纤维膜及其制备方法
WO2016022797A1 (fr) 2014-08-06 2016-02-11 Edwards Lifesciences Corporation Canules à lumières multiples
KR102772441B1 (ko) 2015-08-17 2025-02-26 더 존스 홉킨스 유니버시티 조직 복원용 간엽 세포-결합 복합 재료
WO2017031171A1 (fr) * 2015-08-17 2017-02-23 The Johns Hopkins University Matériau composite se formant in situ pour la restauration tissulaire
CA2995855C (fr) 2015-09-02 2024-01-30 Edwards Lifesciences Corporation Espaceur pour fixer une valve transcatheter a une structure cardiaque bioprothetique
WO2017062375A1 (fr) * 2015-10-05 2017-04-13 The Regents Of The University Of California Polymères thermoréversibles et leurs procédés d'utilisation
US10456245B2 (en) 2016-05-16 2019-10-29 Edwards Lifesciences Corporation System and method for applying material to a stent
SG11201809053UA (en) * 2016-05-16 2018-11-29 Edwards Lifesciences Corp System and method for applying material to a stent
USD846122S1 (en) 2016-12-16 2019-04-16 Edwards Lifesciences Corporation Heart valve sizer
WO2019147497A1 (fr) 2018-01-23 2019-08-01 Edwards Lifesciences Corporation Supports de valvule prothétiques, systèmes et procédés
KR20210034544A (ko) 2018-05-09 2021-03-30 더 존스 홉킨스 유니버시티 향상된 연조직 대체 및 재생을 위한 나노섬유-하이드로겔 복합재료
JP2021522938A (ja) 2018-05-09 2021-09-02 ザ ジョンズ ホプキンス ユニバーシティ 細胞及び組織の送達のためのナノファイバー−ハイドロゲル複合体
USD908874S1 (en) 2018-07-11 2021-01-26 Edwards Lifesciences Corporation Collapsible heart valve sizer
EP4009906A1 (fr) 2019-08-05 2022-06-15 Edwards Lifesciences Corporation Aide au déploiement d'une valvule cardiaque
CN110548187A (zh) * 2019-09-16 2019-12-10 生纳科技(上海)有限公司 一种即时穿刺透析型纳米纤维人工血管
CA3143382A1 (fr) 2019-09-27 2021-04-01 Edwards Lifesciences Corporation Stent de valvule cardiaque prothetique modifie
CN121371320A (zh) * 2025-12-23 2026-01-23 四川大学华西医院 一种基于纳米crispr辅助的仿生组织等效贴片、制备方法及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2000887A1 (fr) * 1988-11-01 1990-05-01 Cecilia S.L. Ku Materiaux thromboresistants et methode de production
US5053453A (en) * 1988-11-01 1991-10-01 Baxter International Inc. Thromboresistant materials and methods for making same
US5989244A (en) * 1994-11-15 1999-11-23 Gregory; Kenton W. Method of use of a sheet of elastin or elastin-based material
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US6610004B2 (en) * 1997-10-09 2003-08-26 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6889082B2 (en) * 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6303136B1 (en) * 1998-04-13 2001-10-16 Neurotech S.A. Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane
US6391333B1 (en) * 1999-04-14 2002-05-21 Collagen Matrix, Inc. Oriented biopolymeric membrane
US20050158362A1 (en) * 2000-06-23 2005-07-21 Wheatley Margaret A. Polymeric, fiber matrix delivery systems for bioactive compounds
US6893431B2 (en) * 2001-10-15 2005-05-17 Scimed Life Systems, Inc. Medical device for delivering patches
US20060085063A1 (en) * 2004-10-15 2006-04-20 Shastri V P Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
WO2007090102A2 (fr) * 2006-01-27 2007-08-09 The Regents Of The University Of California squelettes biomimetiques

Also Published As

Publication number Publication date
EP2023852A2 (fr) 2009-02-18
AU2007258379A1 (en) 2007-12-21
WO2007146261A3 (fr) 2008-12-04
EP2023852A4 (fr) 2012-06-27
KR20090024249A (ko) 2009-03-06
IL195801A0 (en) 2009-09-01
MX2008015695A (es) 2009-02-06
WO2007146261A2 (fr) 2007-12-21
RU2009100654A (ru) 2010-07-20
JP2009540878A (ja) 2009-11-26

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Legal Events

Date Code Title Description
FZDE Discontinued
P22 Classification modified

Free format text: ST27 STATUS EVENT CODE: T-6-6-P10-P22-P110 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CLASSIFICATION MODIFIED

Effective date: 20240828