EP2023852A4 - Squelettes biomimétiques liés à une biomolécule - Google Patents

Squelettes biomimétiques liés à une biomolécule

Info

Publication number
EP2023852A4
EP2023852A4 EP07795989A EP07795989A EP2023852A4 EP 2023852 A4 EP2023852 A4 EP 2023852A4 EP 07795989 A EP07795989 A EP 07795989A EP 07795989 A EP07795989 A EP 07795989A EP 2023852 A4 EP2023852 A4 EP 2023852A4
Authority
EP
European Patent Office
Prior art keywords
biomimetic
skeletons
biomolecule
skeletons related
biomimetic skeletons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP07795989A
Other languages
German (de)
English (en)
Other versions
EP2023852A2 (fr
Inventor
Craig Hashi
Song Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2007/061253 external-priority patent/WO2007090102A2/fr
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Publication of EP2023852A2 publication Critical patent/EP2023852A2/fr
Publication of EP2023852A4 publication Critical patent/EP2023852A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02Peptides being immobilised on, or in, an organic carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727Heparin; Heparan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005Use of materials characterised by their function or physical properties
    • A61L33/0011Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0076Chemical modification of the substrate
    • A61L33/0082Chemical modification of the substrate by reacting with an organic compound other than heparin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02Peptides being immobilised on, or in, an organic carrier
    • C07K17/08Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42Anti-thrombotic agents, anticoagulants, anti-platelet agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
EP07795989A 2006-06-09 2007-06-11 Squelettes biomimétiques liés à une biomolécule Withdrawn EP2023852A4 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US80435006P 2006-06-09 2006-06-09
US86178006P 2006-11-30 2006-11-30
PCT/US2007/061253 WO2007090102A2 (fr) 2006-01-27 2007-01-29 squelettes biomimetiques
US11/668,448 US20070269481A1 (en) 2006-01-27 2007-01-29 Biomimetic Scaffolds
US92492607P 2007-06-05 2007-06-05
PCT/US2007/013736 WO2007146261A2 (fr) 2006-06-09 2007-06-11 Squelettes biomimétiques liés à une biomolécule

Publications (2)

Publication Number Publication Date
EP2023852A2 EP2023852A2 (fr) 2009-02-18
EP2023852A4 true EP2023852A4 (fr) 2012-06-27

Family

ID=40243723

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07795989A Withdrawn EP2023852A4 (fr) 2006-06-09 2007-06-11 Squelettes biomimétiques liés à une biomolécule

Country Status (9)

Country Link
EP (1) EP2023852A4 (fr)
JP (1) JP2009540878A (fr)
KR (1) KR20090024249A (fr)
AU (1) AU2007258379A1 (fr)
CA (1) CA2654840A1 (fr)
IL (1) IL195801A0 (fr)
MX (1) MX2008015695A (fr)
RU (1) RU2009100654A (fr)
WO (1) WO2007146261A2 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1974015A4 (fr) * 2006-01-27 2012-07-04 Univ California Squelettes biomimétiques
WO2010042651A1 (fr) 2008-10-07 2010-04-15 Nanonerve, Inc. Supports polymères fibreux multicouches, procédés de production et procédés d’utilisation
US8591567B2 (en) 2008-11-25 2013-11-26 Edwards Lifesciences Corporation Apparatus and method for in situ expansion of prosthetic device
US8308798B2 (en) 2008-12-19 2012-11-13 Edwards Lifesciences Corporation Quick-connect prosthetic heart valve and methods
WO2011127478A1 (fr) 2010-04-09 2011-10-13 Nanovasc, Inc. Manchon pour greffon et procédé associé
EP2571977B1 (fr) * 2010-05-17 2020-01-08 Yale University, Inc. Système pour inoculer des cellules sur des échafaudages tridimensionnels
US9090863B2 (en) 2010-05-17 2015-07-28 Pall Corporation System for seeding cells onto three dimensional scaffolds
EP2412798A1 (fr) * 2010-07-27 2012-02-01 Gambro Lundia AB Membrane biomimétique pour cultiver des cellules
US9168231B2 (en) 2010-12-05 2015-10-27 Nanonerve, Inc. Fibrous polymer scaffolds having diametrically patterned polymer fibers
EP4190285B1 (fr) 2011-01-06 2026-04-22 Humacyte, Inc. Constructions obtenues par génie tissulaire
CN102698323B (zh) * 2012-05-14 2014-07-23 西南交通大学 一种抗凝血材料的制备方法
ES2470495B1 (es) 2012-12-19 2015-05-14 Universidad De Castilla La Mancha Materiales, métodos y dispositivos para estimular y dirigir la proliferación y migración de progenitores neurales y el crecimiento axonal y dendrítico
KR101526308B1 (ko) * 2013-01-23 2015-06-09 아주대학교산학협력단 생체 내 이식 적용 및 중장기 생체소재 분해 추적용 조영제가 화학적 결합된 생체소재 및 이의 제조방법
TW201546146A (zh) 2014-02-14 2015-12-16 Nissan Chemical Ind Ltd 含活性酯基之纖維製造用組合物及使用其纖維之細胞培養支架材料
CN104153124B (zh) * 2014-07-30 2016-11-02 东华大学 一种柔性稀土氧化物纳米纤维膜及其制备方法
CN104153123B (zh) * 2014-07-30 2016-08-24 东华大学 一种柔性氧化钛纳米纤维膜及其制备方法
WO2016022797A1 (fr) 2014-08-06 2016-02-11 Edwards Lifesciences Corporation Canules à lumières multiples
US12458731B2 (en) 2015-08-17 2025-11-04 The Johns Hopkins University Mesenchymal cell-binding composite material for tissue restoration
WO2017031171A1 (fr) * 2015-08-17 2017-02-23 The Johns Hopkins University Matériau composite se formant in situ pour la restauration tissulaire
CA2995855C (fr) 2015-09-02 2024-01-30 Edwards Lifesciences Corporation Espaceur pour fixer une valve transcatheter a une structure cardiaque bioprothetique
WO2017062375A1 (fr) * 2015-10-05 2017-04-13 The Regents Of The University Of California Polymères thermoréversibles et leurs procédés d'utilisation
EP3457996B1 (fr) * 2016-05-16 2021-03-03 Edwards Lifesciences Corporation Système et procédé d'application de matériau sur un stent
US10456245B2 (en) 2016-05-16 2019-10-29 Edwards Lifesciences Corporation System and method for applying material to a stent
USD846122S1 (en) 2016-12-16 2019-04-16 Edwards Lifesciences Corporation Heart valve sizer
EP3743016B1 (fr) 2018-01-23 2024-10-02 Edwards Lifesciences Corporation Supports de valvule prothétiques, systèmes et procédés
ES3060255T3 (en) 2018-05-09 2026-03-25 Univ Johns Hopkins Nanofiber-hydrogel composites for enhanced soft tissue replacement and regeneration
CA3099732A1 (fr) 2018-05-09 2019-11-14 The Johns Hopkins University Composites nanofibres-hydrogel pour l'administration de cellules et de tissus
USD908874S1 (en) 2018-07-11 2021-01-26 Edwards Lifesciences Corporation Collapsible heart valve sizer
EP4009906A1 (fr) 2019-08-05 2022-06-15 Edwards Lifesciences Corporation Aide au déploiement d'une valvule cardiaque
CN110548187A (zh) * 2019-09-16 2019-12-10 生纳科技(上海)有限公司 一种即时穿刺透析型纳米纤维人工血管
CN114364341A (zh) 2019-09-27 2022-04-15 爱德华兹生命科学公司 改进的假体心脏瓣膜支架
CN121371320B (zh) * 2025-12-23 2026-04-03 四川大学华西医院 一种基于纳米crispr辅助的仿生组织等效贴片、制备方法及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053453A (en) * 1988-11-01 1991-10-01 Baxter International Inc. Thromboresistant materials and methods for making same
WO2007090102A2 (fr) * 2006-01-27 2007-08-09 The Regents Of The University Of California squelettes biomimetiques

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2000887A1 (fr) * 1988-11-01 1990-05-01 Cecilia S.L. Ku Materiaux thromboresistants et methode de production
US5989244A (en) * 1994-11-15 1999-11-23 Gregory; Kenton W. Method of use of a sheet of elastin or elastin-based material
US5607475A (en) * 1995-08-22 1997-03-04 Medtronic, Inc. Biocompatible medical article and method
US6610004B2 (en) * 1997-10-09 2003-08-26 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6889082B2 (en) * 1997-10-09 2005-05-03 Orqis Medical Corporation Implantable heart assist system and method of applying same
US6303136B1 (en) * 1998-04-13 2001-10-16 Neurotech S.A. Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane
US6391333B1 (en) * 1999-04-14 2002-05-21 Collagen Matrix, Inc. Oriented biopolymeric membrane
US20050158362A1 (en) * 2000-06-23 2005-07-21 Wheatley Margaret A. Polymeric, fiber matrix delivery systems for bioactive compounds
US6893431B2 (en) * 2001-10-15 2005-05-17 Scimed Life Systems, Inc. Medical device for delivering patches
US20060085063A1 (en) * 2004-10-15 2006-04-20 Shastri V P Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5053453A (en) * 1988-11-01 1991-10-01 Baxter International Inc. Thromboresistant materials and methods for making same
WO2007090102A2 (fr) * 2006-01-27 2007-08-09 The Regents Of The University Of California squelettes biomimetiques

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZUWEI MA ET AL: "Grafting of Gelatin on Electrospun Poly(caprolactone) Nanofibers to Improve Endothelial Cell Spreading and Proliferation and to Control Cell Orientation", TISSUE ENGINEERING, 1 July 2005 (2005-07-01), United States, pages 1149 - 1158, XP055027680, Retrieved from the Internet <URL:http://online.liebertpub.com/doi/pdf/10.1089/ten.2005.11.1149> [retrieved on 20120521], DOI: 10.1089/ten.2005.11.1149 *

Also Published As

Publication number Publication date
JP2009540878A (ja) 2009-11-26
EP2023852A2 (fr) 2009-02-18
KR20090024249A (ko) 2009-03-06
WO2007146261A2 (fr) 2007-12-21
IL195801A0 (en) 2009-09-01
CA2654840A1 (fr) 2007-12-21
MX2008015695A (es) 2009-02-06
RU2009100654A (ru) 2010-07-20
WO2007146261A3 (fr) 2008-12-04
AU2007258379A1 (en) 2007-12-21

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