CA2659664C - Methodes ameliorees de radiotherapie - Google Patents

Methodes ameliorees de radiotherapie Download PDF

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Publication number: CA2659664C
Authority: CA; Canada
Prior art keywords: seq; artificial sequence; pro; tyr; analogues
Prior art date: 1998-03-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

CA2659664A

Other languages

English (en)

Other versions

CA2659664A1 (fr

Inventor

Kathleen E. Rodgers

Gere Dizerega

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

University of Southern California USC

Original Assignee

University of Southern California USC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-10

Filing date

1999-03-08

Publication date

2013-05-07

1999-03-08 Application filed by University of Southern California USC filed Critical University of Southern California USC

1999-09-16 Publication of CA2659664A1 publication Critical patent/CA2659664A1/fr

2013-05-07 Application granted granted Critical

2013-05-07 Publication of CA2659664C publication Critical patent/CA2659664C/fr

2019-03-08 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0819—Tripeptides with the first amino acid being acidic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/085—Angiotensins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/32—Angiotensins [AT], angiotensinogen

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Hematology (AREA)
Biotechnology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Vascular Medicine (AREA)
Immunology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Cell Biology (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

CA2659664A 1998-03-10 1999-03-08 Methodes ameliorees de radiotherapie Expired - Fee Related CA2659664C (fr)

Applications Claiming Priority (13)

Application Number	Priority Date	Filing Date	Title
US7738298P	1998-03-10	1998-03-10
US60/077,382		1998-03-10
US8126298P	1998-04-09	1998-04-09
US60/081,262		1998-04-09
US8367098P	1998-04-30	1998-04-30
US60/083,670		1998-04-30
US9009698P	1998-06-19	1998-06-19
US60/090,096		1998-06-19
US9021698P	1998-06-22	1998-06-22
US60/090,216		1998-06-22
US9995798P	1998-09-11	1998-09-11
US60/099,957		1998-09-11
CA002323237A CA2323237C (fr)	1998-03-10	1999-03-08	Methodes ameliorees de radiotherapie

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002323237A Division CA2323237C (fr)	1998-03-10	1999-03-08	Methodes ameliorees de radiotherapie

Publications (2)

Publication Number	Publication Date
CA2659664A1 CA2659664A1 (fr)	1999-09-16
CA2659664C true CA2659664C (fr)	2013-05-07

Family

ID=27557165

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA002323237A Expired - Fee Related CA2323237C (fr)	1998-03-10	1999-03-08	Methodes ameliorees de radiotherapie
CA2659664A Expired - Fee Related CA2659664C (fr)	1998-03-10	1999-03-08	Methodes ameliorees de radiotherapie

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
CA002323237A Expired - Fee Related CA2323237C (fr)	1998-03-10	1999-03-08	Methodes ameliorees de radiotherapie

Country Status (5)

Country	Link
EP (1)	EP1061937A1 (fr)
JP (1)	JP3728400B2 (fr)
AU (1)	AU744799B2 (fr)
CA (2)	CA2323237C (fr)
WO (1)	WO1999045945A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6730775B1 (en)	1999-03-23	2004-05-04	University Of Southern California	Methods for limiting scar and adhesion formation
US7338938B2 (en)	1999-05-10	2008-03-04	University Of Southern California	Methods for treating a patient undergoing chemotherapy
AU2002308522A1 (en) *	2001-05-01	2002-11-11	University Of Southern California	Methods for inhibiting tumor cell proliferation
CN1529697B (zh)	2001-05-31	2010-09-22	维科尔药物公司	用作血管紧张素ⅱ激动剂的三环化合物
WO2011120032A1 (fr)	2010-03-26	2011-09-29	University Of Southern California	Méthodes pour traiter des lésions combinées de radiation et thermiques
EP2555760B1 (fr)	2010-04-06	2019-10-16	Synedgen, Inc.	Derives de chitosane pour le traitement de la mucosite ou de l'ulceration
JP2013533315A (ja) *	2010-08-10	2013-08-22	ユニバーシティーオブサザンカリフォルニア	細胞移植における、及びノロウイルス感染症を防止／治療する薬剤としてのアンジオテンシンｉｉ（１−７）の使用
EP2455388A1 (fr)	2010-11-23	2012-05-23	LanthioPep B.V.	Nouveaux agonistes du récepteur 2 (AT2) de type angiotensine et leurs utilisations
US20150050250A1 (en) *	2012-04-05	2015-02-19	University Of Southern California	Cell therapy technology to deliver radio-protective peptides
US8557958B1 (en)	2012-06-18	2013-10-15	Tarix Pharmaceuticals Ltd.	Compositions and methods for treatment of diabetes
WO2014047506A1 (fr)	2012-09-20	2014-03-27	Synedgen, Inc.	Procédés pour le traitement ou la prévention de dommages résultant d'un rayonnement, d'un trauma ou d'un choc
US8633158B1 (en)	2012-10-02	2014-01-21	Tarix Pharmaceuticals Ltd.	Angiotensin in treating brain conditions
US9333233B2 (en)	2014-02-25	2016-05-10	Tarix Pharmaceuticals Ltd.	Methods and compositions for the delayed treatment of stroke
EP4007592A1 (fr)	2019-08-02	2022-06-08	LanthioPep B.V.	Agonistes du récepteur de l'angiotensine 2 (at2) destinés à être utilisés dans le traitement du cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE457055B (sv) *	1986-08-18	1988-11-28	Ferring Ab	Topisk straalskyddsgel foer mukosa innehaallande kaerlsammandragande substanser
US5015629A (en) *	1989-06-26	1991-05-14	University Of Southern California	Tissue repair
WO1995008565A1 (fr) *	1993-09-24	1995-03-30	The University Of Southern California	Utilisation d'analogues d'angiotensine ii pour la reparation tissulaire
WO1997034627A2 (fr) *	1996-03-19	1997-09-25	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.	Protection de cellules hematopoietiques durant une chimiotherapie ou une radiotherapie

1999
- 1999-03-08 EP EP99911273A patent/EP1061937A1/fr not_active Withdrawn
- 1999-03-08 JP JP2000535359A patent/JP3728400B2/ja not_active Expired - Fee Related
- 1999-03-08 AU AU29957/99A patent/AU744799B2/en not_active Ceased
- 1999-03-08 WO PCT/US1999/005194 patent/WO1999045945A1/fr not_active Ceased
- 1999-03-08 CA CA002323237A patent/CA2323237C/fr not_active Expired - Fee Related
- 1999-03-08 CA CA2659664A patent/CA2659664C/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU744799B2 (en)	2002-03-07
WO1999045945A1 (fr)	1999-09-16
EP1061937A1 (fr)	2000-12-27
CA2323237A1 (fr)	1999-09-16
CA2323237C (fr)	2009-05-19
JP2002506042A (ja)	2002-02-26
AU2995799A (en)	1999-09-27
JP3728400B2 (ja)	2005-12-21
CA2659664A1 (fr)	1999-09-16

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Date	Code	Title	Description
2009-01-26	EEER	Examination request
2016-04-19	MKLA	Lapsed	Effective date: 20160308

Publication	Publication Date	Title
US7776828B2 (en)	2010-08-17	Radiation therapy methods
US6455500B1 (en)	2002-09-24	Radiation therapy methods
US6239109B1 (en)	2001-05-29	Method of promoting erythropoiesis
AU737058B2 (en)	2001-08-09	Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
US6248587B1 (en)	2001-06-19	Method for promoting mesenchymal stem and lineage-specific cell proliferation
AU759285B2 (en)	2003-04-10	Methods to increase white blood cell survival after chemotherapy
CA2659664C (fr)	2013-05-07	Methodes ameliorees de radiotherapie
WO1999026644A9 (fr)	2000-05-25	Procede favorisant la proliferation et la differentiation des cellules hematopoitiques et mesenchymateuses
MXPA00008843A (en)	2001-07-09	Improved radiation therapy methods
EP1410801B1 (fr)	2013-04-10	Procédé favorisant la prolifération et la différentiation des cellules hématopoitiques
MXPA00007509A (en)	2001-07-03	Method of promoting erythropoiesis
MXPA00011112A (en)	2001-07-31	Methods to increase white blood cell survival after chemotherapy